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    In recent years, many domestic industrial belts have successively joined the cross-border e-commerce track, and "cross-border e-commerce+industrial belt" has become one of the main forms of foreign trade. In 2024, the domestic industrial belt will face not only the cross-border blue ocean, but also the long-term high-quality sea going. The reporter’s recent visit found that some cross-border e-commerce platforms are helping the industrial belt to expand into a "new blue ocean and new growth pole" through digital means, and promoting the leap of "Made in China" in the international market competitiveness and brand power.

   Cross-border e-commerce empowers industrial belts to expand markets.

    Industrial cluster is an important carrier to promote the high-quality development of regional economy. At present, there are hundreds of light industrial clusters in China, which play an important role in regional economy. In recent years, major cross-border e-commerce platforms have begun to increase cooperation with industrial belts to help local enterprises expand overseas business opportunities more accurately and efficiently through in-depth services.

    In September 2023, Xiyin, a cross-border e-commerce platform, announced the launch of the national 500-city industrial belt plan. Within three years, it will go deep into the national 500-city industrial belt, connect the industrial belt with digital trade and digital flexible supply chain, and provide integrated empowerment from production to market sales to brand growth, helping the industrial belt expand the global market and gain brand promotion. The reporter learned that through the continuous deepening of the 500-city industrial belt going to sea plan under the platform model, the flexible supply chain model of "small single and quick response" produced by Xiyin on demand is splitting from the clothing industry to more industries, helping the industrial belt to go to sea with cross-border e-commerce, and at the same time, empowering this set of capabilities to more industrial belt sellers through platform.

    Going out to sea is not the digestion of excess capacity, but the flexible supply chain makes the market demand and supply more match. By cultivating new models and new formats, the productivity of industrial belts will be improved, and at the same time, small and medium-sized sellers will be realized. In the process of internationalization of China’s manufacturing industry, domestic characteristic industrial belts need to build their own competitive advantages in order to win. With the help of updated digital ideas and digital means, they can realize efficient resource allocation and accelerate innovation, and finally realize the overall capacity transformation and upgrading of industrial belts.

    According to the Insight Report of Cross-border E-commerce Industry 2023 Industry Belt Brand Going to Sea released by Billion Think Tank, "Cross-border E-commerce+Industry Belt" provides a strong impetus for high-quality going to sea. Cross-border e-commerce industrial belts in China have their own characteristics. With the continuous release of policy dividends, many traditional foreign trade industrial belts have achieved global business expansion through cross-border e-commerce.

   From product to brand.

    At present, China’s industrial belt has entered a new stage of intensive brand going out to sea from extensive high-speed growth. Under the background of the state’s support for the development of new foreign trade formats, many traditional foreign trade industrial belts have been actively transformed by relying on cross-border e-commerce channels and digital service tools, further focusing on brand building and global development.

    In the eyes of the industry, one way for the industry to take the brand to the sea is to take the flexible supply chain as the support and embark on the road of brand internationalization through the cross-border e-commerce platform; The other is that trade-oriented businesses transform and upgrade from distributing goods to brands, and build their own brands with the help of cross-border e-commerce platforms.

    Building its own brand and strengthening its brand power are regarded as the inevitable trend of "Made in China". Insiders pointed out that cross-border e-commerce platforms not only empower more industrial belt sellers with flexible supply chain capabilities, but also actively assist industrial belt sellers to build brand power together. The platform helps industrial belt sellers to improve a series of capabilities including product development, market trends, compliance management and supply chain management by empowering them with one-stop services. For the industrial belt, the future is not only the product going out to sea, but also the overall ability and brand power of the industrial belt going out to sea and upgrading. If the industrial belt wants to go to sea, it must achieve high-quality going to sea, and the ultimate benefit will be the comprehensive competitiveness of the whole "Made in China".

    Deng Nan, the seller of wig industry belt, paid attention to the demand of overseas consumers for wigs in his early years. Through the online Xiyin platform, the humble niche products achieved sales of 50,000 US dollars in the first month; Three years later, this number has grown to $2 million.

    "At present, industries driven by cross-border e-commerce platforms are brought out to sea, allowing China’s high-quality supply chain to directly face international consumers, opening up new international markets and promoting industrial upgrading." Zhao Lingyi, chief analyst of Shen Wanhongyuan’s research on commerce and retail, told reporters that the new format of going to sea promoted by "cross-border e-commerce+industrial belt" will further promote the transformation of China’s manufacturing industry into a China brand with independent design concept and strong market competitiveness, thus occupying a more important position in the global value chain.

   Digital innovation drives the development of industrial belt

    Last year, the General Office of the State Council issued an opinion on promoting the stable scale and excellent structure of foreign trade, proposing to support foreign trade enterprises to expand their sales channels and cultivate their own brands through new formats and new models such as cross-border e-commerce, encouraging all localities to combine their industrial and endowment advantages, innovate and build a comprehensive cross-border e-commerce experimental zone, actively develop the "cross-border e-commerce+industrial belt" model, and drive cross-border e-commerce enterprises to export to enterprises.

    Domestic emerging cross-border e-commerce platforms such as Xiyin, AliExpress and Tik Tok Xiaodian have attracted a large number of consumers and sellers through their own characteristics and unique development models, and gradually occupied an important position in the global e-commerce market. In the future, domestic cross-border e-commerce enterprises are expected to fully benefit from the continuous high penetration rate of global e-commerce and the cost-effective advantage of "Made in China" to drive the rapid development of the domestic cross-border e-commerce market. In addition, sellers related to brand going out to sea and manufacturing going out to sea are expected to benefit from the traffic dividend brought by the emerging cross-border e-commerce platform in China.

    "New advantages need to be established in the process of manufacturing internationalization. China’s manufacturing industry must take the road of increasing added value in the future. The added value comes from innovations in design, technology and products, as well as the improvement of brand power. " Hu Qimu, chief researcher of digital economy think tank, said that enterprises can make the supply chain more efficient through digital means, realize personalization and improve overall efficiency at the same time.

    Hu Qimu believes that the "cross-border e-commerce+industrial belt" model is to use digital tools to help businesses continuously optimize the supply chain, solve the problem of production balance through flexible small orders, and then digitally manage the whole process of a large number of fragmented orders, so as to realize flexible and standardized production, improve quality and efficiency, and empower more industrial belts to build new quality productivity and brands to go to sea. (Reporter Gao Shaohua)

Yang Jianfei: Computational Medicine Promotes Accurate Clinical Trials.

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Yang Jianfei, Chief Scientific Officer of Zheyuan Technology

Computational medicine needs to be composed of interdisciplinary teams and platforms. By integrating supercomputing system, AI platform, molecular and clinical data, massive literature and biological information, it can realize effective analysis and calculation of drug development and assist decision-making.

Taking an anti-tumor drug in our pipeline as an example, we read all the literatures of the target disease by using the "TWIRLS stick" of the computational medicine platform, first we have all the scientific knowledge known on the earth at present, and then we analyze the digital twins of patients in the patient database in a data-driven way to obtain the disease mechanism, specific targets and "portraits" of patients.

As we all know, the tumor is heterogeneous in time and space, and the immune system around the tumor is particularly complex. Therefore, only by having an accurate "portrait" of the patient’s tumor and accompanying diagnosis can we enter the stage of accurate clinical trials.

Through the computational medical platform, we established the response mechanism model of CDK4/6 inhibitor, and the effectiveness of this model was verified by the data of TCGA and Chinese patients. Then we put this drug currently used to treat breast cancer on the computational medical platform to study whether it has other applicable diseases. It was found that the model score of chordoma was very high, so we established cooperation with shanghai changzheng hospital and saw that some patients achieved partial remission in the third week after taking the drug. Although this drug has not yet entered the clinical trial stage, as long as it is carried out in accordance with the norms of computational medicine platform, we are confident to achieve truly accurate clinical trials.

Peng Ao: Behind the clinical success rate from 2% to 21%

Peng Ao, Project Management Team Leader of Pfizer China Product Line

The efficiency of Pfizer’s new drug research and development has increased from 2% to 21%. I think we can sum up three experiences. First, accurate positioning, clear their own specific advantages in the field of biology. Pfizer currently focuses on internal medicine, immunity and inflammation, oncology drugs and vaccines. Second, choose the drug mode. At present, more complex and novel molecular entities account for more and more in our pipelines. Thirdly, the decision-making adheres to two principles. First, quantitative POM analysis is carried out in the first and second phase of the experiment, which can help the success rate of the second phase reach 40%; The second is to plan again. If the first direction of clinical research and development fails, then we will transform it and try again in another direction. If there is a very clear biological basis, our success rate can reach 31%.

Ertuglifozin is a SGLT-2 hypoglycemic agent, and a large number of technologies and methods related to computational medicine are used in its research and development, including systematic pharmacological model and Emax Model. Using this model, the highest hypoglycemic effect of the drug can reach 77%. Meta-analysis shows that the drug has the highest hypoglycemic level among similar products. This is a typical case of using model or computational medicine to guide drug research and development.

The US Food and Drug Administration has begun to build a framework for digital health tools. I believe that after the introduction of the framework, the guiding principles of the corresponding rules will also be introduced, which will guide the application of some new drug research and development more specifically and deeply.

Tang Yu: The insights generated by computational medicine need to be verified clinically.

Tang Yu, Executive Director of the Office of Drug Clinical Trial Research Center, Cancer Hospital, China Academy of Medical Sciences

Computational medicine has produced a large number of insights by analyzing massive data, but how to prove that these insights are authentic and can be used in clinical practice through clinical trials?

The first case is to verify the specific answer given by computational medicine to a specific problem, such as verifying whether the first innovative drug under the guidance of AI can treat pancreatic cancer. The second is based on massive data to verify whether the treatment mode formulated by AI for individual patients or groups is better.

In the course of such an experiment, we need to consider several issues:

First, the consistency of the AI model. When we want to prove that an algorithm or an AI-based paradigm can guide medical care, we must ensure the consistency of the paradigm and not make it change irregularly.　

Second, it is necessary to consider whether there is an accessible clinical treatment for a class of patients with more concentrated biological characteristics found by AI model. If there is no targeted treatment, although this model can guide the prognosis of patients, it is difficult to change the existing treatment methods.

Finally, establish a model that can not only explain the results, but also explain the mechanism, so as to better combine human wisdom with the wisdom of computer based on data integration.

At present, we are carrying out an umbrella research design, focusing on soft tissue sarcoma. Although the overall incidence of the disease is not high, there are nearly 100 subtypes. Our anti-vascular targeted drugs have shown excellent effects in individual subtypes, but the overall effect is still not ideal. Therefore, we hope to use Turing Darwin’s laboratory’s in-depth analysis of the whole sarcoma mechanism and digital twin technology to find drugs with ideal curative effect and high accessibility.

Niu gang: the big disease model changes the new paradigm of drug research and development

Niu Gang, Director of Turing Darwin Laboratory

In today’s medical field, we are committed to collecting and utilizing all kinds of disease-related data, looking for clues of logical unity for diseases, and establishing complex and real mechanism portraits. But the key lies in how to understand the so-called mechanism and who is the subject of the complex mechanism?

We have built and trained a brand-new AI method-"Genome Shotgun Damage Assessment Process" (DAGG). By inputting the sequence information of human germ line or tumor genome, AI can translate the sequence gobbledygook that human can’t understand into understandable changes in cell function.

According to the information of genome variation, clinicians can use DAGG to judge whether HER2 gene is amplified in tumor cells of breast cancer patients, so as to further clarify the pathological types of patients and provide clearer and more accurate judgments for patients’ diagnosis and treatment.

With the DAGG method, we can also transform the real patient data into the digital twins of the patient and his disease. With the large-scale accumulation of patients’ digital twins in virtual environment, we conducted a large-scale virtual clinical trial for PD-1/PD-L1 monoclonal antibodies. The results showed that the efficacy of most immunodrugs with indications was not ideal.

Therefore, the virtual clinical trial based on digital twins can replace the original clinical trial results that cost tens of billions of dollars. Based on the curative effect data of a small sample of individual indications, the potential indications of other tumor diseases can be inferred. At the same time, according to the biological mechanism directly suggested by the model, the combination scheme and even new molecules can be rationally designed, which saves many clinical development steps and costs and ensures greater benefits for patients.

Shi Rong: Computational Medicine Helps Accurate Diagnosis and Treatment of Breast Cancer

Shi Rong, Secretary General of Cancer Prevention and Treatment Committee of Wu Jieping Medical Foundation.

Breast cancer is the largest cancer in the world. HER2 is a definite prognostic indicator and a predictive indicator of drug treatment effect for breast cancer, but the tumor heterogeneity of HER2 expression is obvious, and the detection method of HER2 can not meet the demand of anti-HER2 treatment. Therefore, studying the etiology of the germ line carried in the germ line genome is not only helpful to deeply understand the pathogenesis of breast cancer, but also helpful to develop new methods and provide prospective judgment for subsequent treatment.

Recently, the artificial intelligence algorithm DAGG independently developed by the computational medicine team revealed the pathogenesis of breast cancer. It is found that the signal pathway function spectrum (APSP) can be obtained by using the DAGG model based on the germline fingerprint rare coding variation data. According to the difference in the distribution of APSP between patients and people with low etiology, a prediction model can be effectively constructed to evaluate the etiological risk of female individuals, and the HER2-positive and HER2-negative breast cancer patients can be effectively distinguished.

The clinical transformation path of breast cancer based on APSP is divided into three steps. The first step is to guide the clinical treatment plan based on the pathological classification of breast cancer by APSP. The second step, based on APSP, is the extremely early diagnosis of women with breast nodules and breast cancer with familial breast cancer genetic history, so as to reduce the proportion of breast cancer patients who enter advanced and advanced stages at the first diagnosis. The third step, breast cancer risk assessment of healthy population based on APSP, fills the gap of the lack of effective primary prevention measures for breast cancer in the world.

Jiang Min: Virtual clinical trial is a new paradigm in the future.

Jiang Min, Director of the Office of National Drug Clinical Trial Institution of Peking University Cancer Hospital

From a global perspective, there have been exploratory studies on virtual clinical trials, but retrospective cases are the main ones. Regarding whether we can carry out prospective virtual trial design and generate higher-level digital evidence to verify the computer simulation model, so as to better guide clinical research, Peking University Cancer Hospital and the computational medicine team collided from the perspectives of technology and experimental requirements, forming a real landing research.

The two sides jointly carried out a parallel virtual clinical research project by using the digital twin model of patients in computational medicine. The purpose of the research is to explore the relationship between the pathogenesis of tumor and the mechanism of anti-tumor drugs. Through the virtual clinical trial, the curative effect of anti-tumor drugs is predicted, and the characteristics and differences of patients are analyzed, so as to optimize the design of clinical trials. This study compares head-to-head with a real clinical study of registered new drugs to verify the consistency between the predicted results of virtual clinical research and the curative effects of real-world clinical trials.

Virtual clinical trial is a new paradigm in the future. With the support of computational medicine technology, the future clinical trial model may be transformed into more accurate clinical trial design, which will bring a more holistic drug research and development idea, which will bring revolutionary changes to the success rate and effectiveness of clinical trials.

Roundtable Forum I: Cognition and Evaluation of Non-consensus and Subversive Technology

Moderator: Li Lei, Associate Research Fellow of Frontier Science and Education Bureau of China Academy of Sciences.

Roundtable forum site.

Lv Benfu (Professor, School of Economics and Management, Chinese Academy of Sciences)The so-called breakthrough innovation mainly depends on three points. First, whether a brand-new track has been developed; Secondly, on the original track, whether its performance-to-value ratio conforms to the law of ten times speed; Third, whether it belongs to the pattern innovation from 0 to 1 depends on the support of industrial policies.

Gu Chengming (Head of Sanofi Greater China Medical Department)The non-consensus stage is the primary stage. As long as it is accepted by the industry, it is considered as consensus, or it is available, which can solve some problems. However, in the field of drug research and development, if you want to be a First-in-Class, it must be a non-consensus. If you become a consensus, it will be Me too.

Zhang Chunming (Vice President of the Western Research Institute of Computing Technology, Zhongke)From a practical point of view, today’s world structure does not support small steps forward, and we must give full play to the ability of large-scale team operations. In terms of innovation, it is indeed possible for computational medicine to open up a brand-new track, so any government department should carefully evaluate it.

Weng Huajian (deputy head of Changning District, Shanghai)In 2021, I first learned about computational medicine. At that time, we envisaged to set up a life science innovation center between Suzhou and Shanghai, specializing in high-end research and development, focusing on computer +Inside and AI+, so as to give full play to the accumulation of digital economy in Changning, Shanghai in the past 20 years, especially the accumulation advantages of talents and innovation ecology. Therefore, from the perspective of the government, we are full of expectations for disruptive innovation technology in computational medicine.

Roundtable Forum II: Investment Logic from the Perspective of Computational Medicine

Moderator: translated by Hu Ming, partner of Mingde Capital.

Roundtable forum site.

Tian Feng (Minister of Industry Service Department of Shanghai Biomedical Industry Promotion Center)The most noteworthy point of the whole AI+ pharmaceutical industry is to change from logical successful practice to probabilistic successful practice, and finally return to logical successful practice. From the perspective of AI+ diseases, developing virtual clinical trials, I think it can effectively reduce the cost of clinical development and improve the success rate in the future.

Jing Xutian (Managing Director of Wuyuan Capital): AI technology has brought some new algorithms and breakthroughs in computing power. In the past, many AI pharmaceutical companies paid more attention to the field of small molecules with the most data and the most mature data, but today we see that more and more algorithms are actually very suitable for doing some new modal drug discovery.

Zeng Yingzhe (Partner of Linear Capital)Before AI technology, we usually build low-dimensional models to solve high-dimensional problems, but the emergence of AI can solve these high-dimensional problems. With more and more data and more powerful computing power, the prospect of AI pharmaceutical is very broad. At present, we are observing what progress the big language model will bring to AI pharmaceutical. It is exciting that some new progress has been made in the field of molecular characterization algorithms.

Ma Rui (partner of Fengrui Capital)We always overestimate the progress of computational medicine in five years, but underestimate the progress it can bring in ten years. I think that in the next three years, macromolecular protein drugs will basically be subverted by AI, just like AlphaFold in 2021 completely solved the problem of structural prediction of single domain proteins. (Photo courtesy of the organizer)

CCTV News:The State Council Press Office held a series of press conferences on promoting high-quality development on the 29th. China National Intellectual Property Administration introduces new measures for trademark application of service business entities.

As of June this year, the number of valid registered trademarks in China has reached 45.909 million, with an average of one valid trademark for every four business entities.

In order to meet the diversified trademark application needs of business entities, China National Intellectual Property Administration has set up 353 trademark business acceptance windows in 31 provinces (autonomous regions and municipalities) to provide face-to-face application and consulting services.

Hu Wenhui, deputy director of China National Intellectual Property Administration, said: "At the same time, we actively promote the electronic processing of the whole process of trademark business, optimize the user experience of online application, and discount the online application fee. At present, the online application rate of trademark registration application has reached 99.7%."

In addition, China has realized the electronization of trademark certificates to meet the application needs of mutual recognition of electronic certificates throughout the country. Strengthen the sharing of enterprise registration data and trademark registration data, and realize the synchronous acceptance and collaborative processing of enterprise change registration and trademark change application in many places.

China National Intellectual Property Administration: In the first half of the year, the intellectual property business developed steadily.

In addition, China National Intellectual Property Administration introduced on the 29th that in the first half of the year, China’s intellectual property industry developed steadily.

In the first half of this year, China authorized 554,000 invention patents, a year-on-year increase of 28.0%; There were 2.463 million registered trademarks, a year-on-year increase of 22.0%.

Ge Shu, deputy director of China National Intellectual Property Administration Patent Office, said: "The number of patent transfer licenses nationwide reached 252,000, up 35.2% year-on-year. The registered amount of patent and trademark pledge financing reached 419.9 billion yuan, a year-on-year increase of 57%, benefiting more than 20,000 enterprises. "

In addition, China issued the Implementation Plan for the Construction Project of Intellectual Property Protection System, with protection centers and fast rights protection centers covering 28 provinces (autonomous regions and municipalities), and handled 21,000 administrative cases of patent infringement disputes in the first half of the year, and the protection of intellectual property rights continued to increase.

Pacific science and technology informationOn August 22nd, Apple’s marketing team did an excellent job in promoting the advantages of its products and chips, even if it meant misleading consumers into believing that they were actually investing in cutting-edge products. Previously, the market generally thought that the iPhone 14 Pro and iPhone 14 Pro Max were equipped with A16 bionic chips manufactured by TSMC in a 4-nanometer process. However, a person familiar with the matter overturned this view. He revealed that Apple internally marked this chip as a 5-nanometer chip, instead of the expected 4 nanometers.

The whistleblower further confirmed that A16 bionic chip was labeled as a 5-nanometer chip inside Apple. This may explain why Apple mentioned in the press release that the M2 Pro and M2 Max chips in the new 14-inch and 16-inch MacBook Pro models are mass-produced on the 5-nanometer process instead of the 4-nanometer process.

On the other hand, Apple’s next-generation A17 bionic chip is determined to adopt TSMC’s most advanced 3 nm process. Due to the transition from 5 nm to 3 nm, the performance leap between A16 and A17 will be huge. It is reported that in the previous benchmark test, compared with the previous generation, A17 bionic chip has improved as much as 31% in single-core and multi-core results.

It is worth noting that this latest news makes the upcoming iPhone 15 Pro and iPhone 15 Pro Max more attractive, because both phones will be equipped with A17 bionic chips. However, the relatively low-priced iPhone 15 and iPhone 15 Plus may use A16 bionic chip.

However, this has also triggered netizens’ speculation, whether A17 is just another product promoted by Apple’s comprehensive marketing promotion, or whether the customized chip is actually designed and mass-produced on a brand-new architecture. Some netizens claimed that TSMC’s 3-nanometer process may only reduce the 5-nanometer nodes, and the real 3-nanometer process should adopt N3E technology. So far, we are disappointed that A16 is not a 4nm component, but this is not surprising, because the company always follows this practice.

　　From 0: 00 on July 12th to 24: 00 on 14th, Yunnan Menglian Dai, Lahu and Wa Autonomous County carried out a general survey of free nucleic acid detection for all employees, and more than 150,000 people were detected, all of which were negative. Immediately, Menglian County lifted the county’s closed management and resumed normal production and living order. However, when entering and leaving Menglian Card Point, it will continue to strictly enforce that all people leaving Menglian must hold a negative certificate of valid nucleic acid test within 3 days, check their ID cards, scan the code bright (that is, scan Yunnan health code and communication big data travel card), and measure their body temperature without abnormality before they can travel; Personnel from high school risk areas or those who have lived in middle and high risk areas in the past 14 days are suspended from entering Bangladesh. If it is really necessary to enter Bangladesh, negative proof of nucleic acid test within 3 days is required; Persons from other provinces (especially key provinces, cities and districts of telecom fraud) who intend to enter Bangladesh without justifiable reasons (unable to provide valid certificates such as business license, real estate certificate, residence permit, enterprises, institutions and villages (communities)) will be persuaded to return. (CCTV reporter Li Jinsong)

Cctv newsAccording to the WeChat WeChat official account news released by Sanya, on the morning of March 17, 2023, the video of "A tour guide in Sanya suspected that tourists scolded tourists because they didn’t shop" attracted the attention of the media and netizens. The Sanya Municipal Bureau of Tourism and Culture, Radio, Film and Television Sports, the Municipal Comprehensive Administrative Law Enforcement Bureau and other departments attached great importance to it and immediately organized an investigation.

After investigation, the tour group in the video was a four-day and three-night individual tour group received by Hainan Xinxianglian International Travel Service Co., Ltd. (registered at Room B207, Floor 2, Building B, Shengshenghuiyu, No.35 Nansha Road, Longhua District, Haikou City) on February 23, 2023. The tour guide was Yang Moumou (female), and his tour guide card was attached to Hainan Xinhuanyou International Travel Service Co., Ltd. (registered at Floor 4, Blue Sky Plaza, No.19 Heping Avenue, Heping South Street, Meilan District, Haikou City

At present, the Comprehensive Administrative Law Enforcement Bureau of Longhua District of Haikou City has ordered travel agencies to improve the service quality of employees and tour guides; The tour guides involved have made a Record of Investigation and Inquiry, which will be handled according to the law. Citizens and tourists can call the Sanya municipal government service hotline at 0898-12345 immediately if they find illegal business practices in the tourism market. In view of the illegal acts in the tourism market, the relevant departments of our city will severely investigate and deal with them and will never tolerate them.

Comprehensive improvement of tourism market and environment in Sanya City

Work leading group office

March 17, 2023

If you don’t go to sea, you are out.In recent years, e-commerce "going out to sea" has been frequent., major e-commerce platforms are also there.Constantly update the "gameplay" to meet the needs of merchants and cope with market changes.according toGeneral Administration of CustomsThe latest statistics released show that in the first half of the year, the import and export volume of cross-border e-commerce in China reached 1.22 trillion yuan, up 10.5% year-on-year, which was 4.4 percentage points higher than the overall growth rate of China’s foreign trade in the same period.

As a "happy hometown" for countless cross-border e-commerce sellers,1688 is also making efforts in cross-border e-commerce. On September 11th, 2024, at the press conference of "1688 Selection Center and 1688 Businessmen’s Festival" held in Taizhou, the person in charge of the 1688 Selection Center revealed that 1688 should rely on the offline selection center to make heavy investment in the industrial belt. At the same time, 1688 is aiming at the new outlet of cross-border e-commerce and laying out the whole link ecology of cross-border e-commerce.

Create the shortest link matching supply and demand

Nowadays, the supply of industrial belts is the focus of major platforms, and 1688 is no exception. At the press conference, the person in charge of the 1688 product selection center believes that the most advanced and shortest path to realize the digitalization of the industrial belt is to establish an online and offline integrated operation and service model. Therefore, the 1688 product selection center is jointly built by the government, chain owners, 1688 and the source manufacturers of industrial belts. Through the "four-in-one" online and offline operation mode, a business ecosystem of industrial belts with digital supply chains is jointly built, not just an offline entity.

The offline product selection center is set up, endorsed and guided by the government. The chain owner of the local supply chain is responsible for the daily operation, and the industrial belt factory is stationed to jointly aggregate the high-quality goods of the industrial belt, create a "front office and back warehouse" model, and provide comprehensive services integrating enterprise services and warehousing and logistics. Online, 1688 has also built a digital store in the product selection center, providing technical and digital capabilities, and relying on the advantages of 1688′ s entire network source, it has achieved omni-channel sales and efficient matching between supply and demand.

Image source: 1688

As of September 2024, 1688 has signed a cooperation agreement to build 12 product selection centers, of which 4 have been opened, and 6 are expected to open in September this year, mainly in Taizhou, Yiwu, Yongkang and Jiaxing in Zhejiang, Shenzhen, Guangzhou, Shantou and Jieyang in Guangdong, and Zhengzhou in Henan. In the next three years, 1688 will continue to deeply cultivate 177 key industrial belts in 40 cities based on the core production areas and sales areas.

"In fact, what we hope to bring to the source factory of the industrial belt is the most efficient and shortest path business model. The core positioning of the product selection center is’ visiting the industrial belt in one day’. Whether you are visiting the industrial belt or purchasing it, whether you are an online digital shopping center or an offline shopping center, you can see the ability and panorama of the industrial belt, making it easy to purchase in one stop. " The person in charge of 1688 selection said.

1688 has been deeply ploughing and reinvesting in the industrial belt. Now, in 1688, it is necessary to increase investment and put the core strategic projects into the industrial belt one after another. The 1688 member store will rely on the offline product selection center as the springboard and bridgehead, go out from 1688, and open stores from online to offline at the same time, and establish white-label supply chain supermarkets for Sam member supermarkets and costco (opening customers) under the marking line.

It is reported that the goal of developing member stores in 1688 is to build a "global member store driven by white brand supply chain", and to provide services to members online and offline. At present, the number of paid members of 1688 has reached nearly 10 million, exceeding the scale of paid members of Sam in China, and the number of members in the past year has increased by more than 400% year-on-year.

The supply of 1688 offline member stores will be relatively vertical, and different sources will be supplied according to different industrial belts. Next, 1688 will gradually combine the characteristic trend products of various industrial belts with offline product selection centers, so that every member of 1688 can buy the national characteristic white-brand products locally.

At the same time, 1688 YEATION will also rely on some product selection centers, unite with China’s major brand foundries and factories with strong R&D and manufacturing capabilities, and launch 1688 YEATION’s branded products, further giving play to the advantages of large-scale supply chain, so that 1688 members can enjoy more differentiated quality products.

Output "supply chain solutions" that can be integrated.

Product selection is the primary link of cross-border e-commerce. The person in charge of the 1688 product selection center revealed that the "Domestic YEATION" was launched in 1688. Now, in order to better help cross-border e-commerce sellers to select products, the "Cross-border YEATION" will be launched. According to the latest consumption trends of overseas consumers, products that meet the needs of cross-border e-commerce sellers will be screened out to provide guarantee for product quality and back-end services.

Image source: 1688

At present, 1688 focuses on just-needed categories of consumption, which, in summary, are eating, drinking, having fun, daily use and beauty trends. For example, Zhengzhou’s food, Shantou’s toys, Taizhou’s storage, Yiwu’s Ribai, Guangzhou’s beauty cosmetics, Shenzhen’s digital products, Jieyang’s household appliances, etc. are all core categories of the industrial belt and just-needed categories.

The person in charge of the 1688 product selection center said: "1688′ s cross-border e-commerce business does not do overseas 2C, but serves overseas small B buyers. 1688 is to help cross-border e-commerce buyers and sellers achieve more efficient supply and demand matching in an ecological way. For example, in cooperation with overseas independent stations, the products are directly laid on the independent stations by means of source-seeking communication. In addition, many large and medium-sized overseas buyers now have their own ERP systems, which will involve product inventory and supplier management. 1688 will be embedded in ERP based on their demands, and one-click distribution of goods will be carried out."

Specifically, 1688 is to turn China’s digital supply chain into a digital "chip"-like solution and capability that can be integrated, and then do cross-border cooperation, which is neither Apple mode nor Android mode, but more like Intel mode.

In the early days of cross-border e-commerce, cross-border e-commerceThe links are deep and long, and many links are impassable. Buyers find it hard to use, so they need to hire a Chinese agent or set up an office in China to find someone to choose goods on 1688. Now these links are open, and the interface is more friendly, turning into a digital "chip", plug and play.

When overseas buyers get the digital "chip", it is equivalent to getting the capacity of the whole China industrial belt, which is the largest digital assembly and digital supply chain supplied by the source. Buyers can also customize their needs. For example, if they choose Vietnam, 1688 will help them choose those supplies that meet the needs of Vietnam, recommend pallets that Vietnamese young people like, and provide supporting services for localized performance.

In the cross-border supply chain, 1688 is ready to export an integrated "supply chain solution", that is, a digital "chip" that integrates the white-label supply of China industries and can be "plug and play". Overseas buyers can only make inquiries on 1688 before, but now they can use AI to handle customs clearance, foreign exchange settlement, local distribution, and even the return and exchange of some key countries are done by 1688 and ecological partners. The core of "1688" is to help pallets go out to sea, with emphasis on the waist-high competitive and dynamic supply of China industries.

Cover/Figure Worm Creativity

(Source: Hugo Express)

　　China news agency, Beijing, March 1 ST: China’s promotion of a new round of "trade-in" will bring many benefits

　　China News Service reporter Liu Liang

　　The fourth meeting of the Central Financial and Economic Committee held recently proposed to encourage and guide a new round of large-scale equipment renewal and trade-in of consumer goods, and make detailed arrangements for this. According to industry analysts, accelerating product upgrading is an important measure to promote high-quality development, which will not only help promote investment and consumption growth, but also bring many benefits.

　　Realistic consideration of "trade-in"

　　A new round of "trade-in" has long been a policy deployment. At the end of 2023, the Central Economic Work Conference proposed to promote large-scale equipment renewal and trade-in of consumer goods by improving standards such as technology, energy consumption and emissions. The fourth meeting of the Central Financial and Economic Committee will further clarify the deployment.

　　Ma Mao, Vice Chairman of the Presidium of the Board of Directors of China Household Electrical Appliances Service and Maintenance Association, said that a new round of "trade-in" is a realistic need to stimulate investment and consumption. At present, China’s macro-economy is generally in the recovery period after the epidemic, and the trend of recovery has not changed. However, the home appliance industry generally faces some difficulties and challenges, especially the lack of effective demand and the weak willingness of residents to consume and invest in enterprises. Promoting a new round of "trade-in" will help to expand the scale of consumption, improve investment expectations and drive long-term investment growth of enterprises.

　　Promoting the trade-in of the old consumer market and industrial transformation and upgrading complement each other. Wan Zhe, a professor at Beijing Normal University and executive director of China Modern Finance Society, said that at present, China’s new energy industry is developing rapidly, and it is in the forefront of the world in many technologies, products, talents, management and brands. The market share of green, digital and intelligent products and equipment is increasing day by day, which has its own market rules. At this time, it is also in line with the logic of economic development to propose equipment renewal.

　　Multi-point deployment of "trade-in"

　　The meeting made detailed arrangements for the new round of "trade-in". The meeting proposed to adhere to the market-oriented, government guidance, encourage the advanced, eliminate the backward, adhere to the standard guidance, and improve in an orderly manner. In Wan Zhe’s view, the previous trade-in was mostly government-led and financial support, but this time it was carried out in a government-led and enterprise-led way, and the market-oriented tone of letting enterprises "play the leading role" can make the docking between supply and demand more efficient.

　　The meeting also gave "guidance" in specific areas and links, such as promoting the upgrading and technological transformation of various production equipment and service equipment, encouraging the trade-in of traditional consumer goods such as automobiles and household appliances, and promoting the trade-in of durable consumer goods. Promote large-scale recycling, and strengthen the development of "trade-in+recycling" logistics system and new models.

　　Ma Mao pointed out that promoting large-scale recycling and strengthening the development of "trade-in+recycling" logistics system and new model is a very important part of the trade-in work. In recent years, consumers have a certain understanding of trade-in, but there are also some problems, such as not bad, inconvenient and unreasonable depreciation price. Only by unblocking the recycling channels, solving the difficult points in recycling and solving the inconvenience of consumers to "send the old" can we better promote the "replacement".

　　Many advantages of "trade-in"

　　Promoting a new round of "trade-in" will bring many benefits.

　　From the consumer’s point of view, Ma Mao believes that by exchanging old products for new ones, the safety hazards caused by products that have been in service for extended periods can be eliminated for consumers. At the same time, providing consumers with green, intelligent, new technologies and experienced products and services will meet their needs for high-quality life. Furthermore, with the financial support provided by the central finance, local governments and enterprises, consumers will get more consumption benefits.

　　From an industry perspective, the market potential behind it is worthy of attention. Many industry research reports pointed out that "trade-in" will benefit the release of demand for home appliances. For example, according to the Capital Securities Research Report, the number of air conditioners and range hoods in rural areas is much lower than that in urban households. It is expected that a new round of household appliances "trade-in" will promote the implementation of the consumption policy, which will accelerate the increase of the number of range hoods, air conditioners and other categories in rural areas while upgrading the old household appliances. Guotai Junan Research Report predicts that this trade-in policy is expected to promote the valuation of home appliance enterprises.

　　In Ma’s view, a new round of "trade-in" will help enterprises to increase technology investment, eliminate product lines with backward production capacity, and develop more products with new technologies. At the same time, the government policy focuses on guiding and solving the problems encountered by enterprises in the trade-in process, which will facilitate enterprises to better promote trade-in and recycling, and help the country achieve the goal of "double carbon" in the long run. (End)

In this era of information explosion, the star’s every move is closely watched. Recently, Wang Baoqiang has once again become the focus, and has been involved in the whirlpool of public opinion because of its charity storm and the subsequent’ fraud door’. Why did this actor, who was once considered to be the most human in the entertainment circle, fall into so many controversies? This article will take you to explore the ins and outs of this incident, and let us unveil the truth together.

First, a wonderful beginning: Wang Baoqiang’s "roller coaster" life

Wang Baoqiang’s career is full of ups and downs and glory. From an ordinary farmer to today’s "Billion Film Emperor", he has won numerous applause with his strength. However, in just a few months, he seems to be on the "roller coaster" in the entertainment industry. In October, the news about the collapse of his charity was shocking; Then, in November, there was a "fraud door" with an amount as high as 100 million, which was unbelievable. This series of events seems to imply that Wang Baoqiang is experiencing an unprecedented crisis in the entertainment circle.

Second, the charity storm: people set the fuse for collapse

The cause of the incident originated on October 28th, when a well-known entertainment story revealed that Wang Baoqiang was suspected of charity fraud during the filming of The Octagonal Cage, saying that his image was actually hypocritical. The "little actor"’ s careless complaint quickly triggered a hot discussion among netizens. He not only described the hard life during the filming, but also claimed that Wang Baoqiang’s promise to support school was not fulfilled. For a time, Wang Baoqiang’s "charity design" was hit hard, and many netizens questioned it.

Third, reverse the plot: reveal the true intention of Wang Baoqiang.

With the development of the incident, more truths gradually surfaced. Netizens took the initiative to refute rumors and revealed Wang Baoqiang’s promise to the little actor after the filming. He not only paid 150,000 yuan for each young actor, but also promised to help them finish their studies. Obviously, the opposition did not completely overthrow the true image of Wang Baoqiang, but made things dramatically reversed. More netizens suggested that the careless complaint was not credible, because he already had a considerable economic base, and there were many luxuries in his social account.

Fourth, characterization: Wang Baoqiang’s truth and emotion.

In the entertainment circle, Wang Baoqiang’s truthfulness and simplicity are one of the reasons why he attracts many supporters. Even in the process of his ex-wife Ma Rong absconding with money, Wang Baoqiang still showed his indomitable personality, which made many people feel sympathy for him. In this storm, many supporters have come forward to speak for him, thinking that he has always been a trustworthy person. The hardships of Wang Baoqiang’s childhood life and the story of realizing his dream through hard work later made his image deeply rooted in the minds of many audiences.

V. Fashion and Trend: The Unknown Side of Wang Baoqiang

Although Wang Baoqiang’s recent negative news has dominated the limelight, his performance in the fashion world should not be underestimated. What Wang Baoqiang wears in public often reflects his love for life and his unique understanding of fashion. In the recent red carpet activities, he appeared in a simple but stylish suit and won wide acclaim at the scene. Whether you choose classic black and white collocation or try trendy accessories, Wang Baoqiang can always give people a bright feeling. His fashion concept may not be understood by everyone, but this uniqueness makes him stand out among many stars.

Vi. Hot discussion on social media: the interaction between fans and the public

With the popularity of social media, the interaction between stars and fans has become more frequent. On Wang Baoqiang’s social platform, fans have expressed their views on his events, and the debate between supporters and opponents seems to be endless. Many netizens share their opinions in the comment area, which makes the topic more heated by the coexistence of humor and rationality. It is this kind of interaction that strengthens the connection between Wang Baoqiang and his fans, and also makes this storm the focus of hot discussion on the Internet.

Seven, multi-angle analysis: the opinions of experts and the reactions of ordinary audiences.

For this incident, many industry experts have expressed their views. Some film critics pointed out that the gradual collapse of Wang Baoqiang was not accidental, but the result of the changeable entertainment style and complicated public opinion environment. They believe that once the image of public figures is deeply excavated, it may be greatly reversed. The general audience’s reaction to this incident was polarized. Some viewers said they no longer believed in Wang Baoqiang, while others thought it was just a misunderstanding and needed to give Wang Baoqiang support and understanding.

Eight, the future direction of the event: the story to be continued

Although Wang Baoqiang is facing severe public opinion challenges at present, from the feedback of all parties, things may not have reached the end. With the further development of related events, it will take time to test whether Wang Baoqiang’s personnel structure can be reshaped. No matter how this matter develops, every journey Wang Baoqiang has experienced tells us that the story behind the stars is often more complicated than the characters on the screen.

Generally speaking, this incident in Wang Baoqiang reveals the difficulty and complexity behind the glamorous appearance of the entertainment circle. The construction of a star’s personality requires both talent and hard work, but also persistence and truthfulness. We expect Wang Baoqiang to continue to bring more wonderful works to the audience after the storm, and hope to show a more authentic self in the process.

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