They are all hot pots. Old Beijing hot pot, Chongqing hot pot and Chaoshan hot pot are very different in eating methods.

When we used to talk about hot pot, we always thought of Chongqing hot pot. Nowadays, with the improvement of living standards, people are paying more and more attention to food, and the culture of diet has become a very important part of people’s daily life. Every city has delicious food from all over the country, and hot pot is no longer exclusive to Sichuan and Chongqing, and its figure is all over the country.

Hot pot is a very simple way to eat. It doesn’t need to go through very complicated procedures to make dishes. It just needs to prepare a pot bottom and put the prepared lettuce in the pot bottom to cook. Although eating hot pot has no complicated cooking process, we still need to cook the dishes ourselves, so we also need some skills in the process of eating hot pot. In particular, the order of hot pot dishes is particularly important, because the order of dishes will affect the bottom of the pot, thus affecting the taste of food.

So what should be the correct order of putting vegetables in the pot? How can I put it without affecting the taste at the bottom of the pot and eat the most delicious food? For this reason, I consulted a good friend who has been a manager in a hot pot restaurant for three years. He said that you can see many real senior foodies in the store. The order in which they put food is recorded in their own notebooks, and the waiters in the store follow the record when they see it, so that they can also put food in this order when they eat it themselves in the future. What is the specific order? Share it with everyone today, and then go to eat hot pot later, in this order!

When eating special hot pots in different places, we need to have different orders. After all, the soup bases of hot pots in different places are different, and some even look different. Therefore, we should arrange the correct steps of putting vegetables according to the bottom and pot.

The first kind: old Beijing hotpot

Speaking of hot pot, I have to say old Beijing instant-boiled mutton hot pot, which is the originator of hot pot. Mutton copper pot generally uses clear water, so its soup base is relatively light. When we eat hot pot, we should rinse the sheep’s tail oil first. Listening to this name, we know that the sheep’s tail oil is a piece of pure fat. Putting it into the pot first can make the bottom of the pot not so light. Then we’ll cut the mutton. Hand-cut mutton has a very big feature, even if the plate is upside down, the mutton will not fall off, but will stick tightly to the plate. And there is no blood left on the plate.

The second kind: Chongqing hot pot

Chongqing hot pot is a very famous hot pot, and many people will go to Chongqing specifically to eat an authentic hot pot. The bottom of Chongqing hotpot is not as light as that of old Beijing mutton hotpot. If it is a very authentic hot pot restaurant, it will generally use the bottom of Jiugongge pot. So at this time, we should pay attention not only to the order of the dishes, but also to which grid to put the dishes in. As the name implies, Jiugongge hot pot has nine grids at the bottom of the hot pot, but the grid positions are different and the firepower of the hot pot is different.

The fire power in several squares next to Jiugongge hot pot is relatively small, so you can put cooking-resistant food in these squares, such as meatballs, brain flowers, blood curd, old meat slices and so on. The longer these foods are cooked, the better they taste, so you don’t have to worry about the bad taste when you eat hot pot.

The third kind: Chaoshan hot pot

Chongqing hot pot is a very heavy-flavored hot pot, which is famous for its spicy taste. Many people are not used to this kind of spicy taste, so let’s talk about Chaoshan beef hot pot. The bottom of Chaoshan beef hot pot is very light. When we eat Beijing mutton hot pot, we will rinse the sheep tail oil first. It will be better to eat other meat after there is oil and water in the bottom of the pot, but Chaoshan hot pot is just the opposite. When eating Chaoshan hot pot, we should change from light to greasy, that is, we should eat lean meat first and then fat meat. After rinsing the fat meat, an oil layer will appear in the soup base. At this time, the soup base has become very greasy. We can add vegetables to the hot pot and eat it very refreshing.

Every place has a profound food culture, and hot pot is an important part of our food culture. When eating hot pot, if you can correctly grasp the order of dishes, you can get a better experience of eating hot pot.

Original title: They are all hot pots, but the old Beijing hot pot, Chongqing hot pot and Chaoshan hot pot are quite different in eating methods.

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"Blizzard Coming" was released on November 17th, and Duan Long conquered the audience to explore the case together.

1905 movie network news  In 2017, the film and television market in China set off a strong "crime craze", which made crime fans feel like Chinese New Year every day. The protagonist in this kind of works is usually a "detective" who pursues the truth tirelessly. In this year’s craze, the most eye-catching detectives are Pan Yueming, the "Fine Detective" who grossly received 3.6 billion broadcasts, Qin Hao, the "handsome detective" who was praised for squatting in the toilet in Crime without a license, and Duan Long, the "coldest detective" who just won the Tokyo Best Actor. All three people have achieved a double harvest of word of mouth and popularity. What did they rely on to conquer the audience and "explore the case" together?


Break the classic image of the old "detective"


When it comes to "detective", the classic image represented by Sherlock Holmes has been copied beyond measure, and there is nothing new, which leads to the audience’s aesthetic fatigue. However, these three criminal works that have attracted the most attention recently, Chasing the Murder in a White Night, Crime Without a License and Blizzard Coming, began to reject the classics and opened up a non-facebook road.


Guan Hongfeng, an old criminal policeman played by Pan Yueming in "White Night Chasing Murder", had to appear in the police force day and night with his twin brother who was suspected of murder because of his fear of night. Qin Hao’s criminal police Yan Liang, played in Crime Without a Certificate, is more like a "devil in the world" with a bad temper.

Duan Long played in "Blizzard is Coming""Detective Yu" Guowei Yu, whose real identity is a worker in the security department of a state-owned factory, pursued the murderer "desperately" in order to become a real policeman. Surprised or not? Surprised? These innovative "detective" images and plot settings make the audience fascinated while they can’t fathom the plot of the characters, and feel the deep sincerity from the screenwriter.


Refusing to open the hanging mode "insults" the audience


Compared with the "detective" images in previous criminal works, these three characters are down-to-earth and no longer take the road of "insulting the audience’s IQ". Adhering to the principle of "never plug in", Guan Hongfeng in "White Night Chasing Murder", as an old criminal policeman, naturally belongs to the stereotype reasoning style and pays attention to detective push.The process of management.


First, the forensic doctor will judge the way of death, the time of death, and the weapon used by the murderer. Then the technical team will retrieve the monitoring around the crime scene, extract key information from it, and then dispatch personnel to conduct investigation. Yan Liang, a young policeman who is "a social person with a wild road" in the crime of undocumented, belongs to the social school.Reasoning, focusing on criminal motives. In the absence of evidence, through their keen intuition and logic "forced" to pressure each other.


"Detective Yu" played by Duan Long in "The Blizzard is Coming" uses his own "fishing" method to solve the case, throwing out lures such as keys and women to lure the snake out of the hole. As a worker in the 1990s, heFactory security workers, using this method is the most real and reasonable. It is this real style that makes the plot of the two men chasing after the murderer appeared in the rain extremely exciting and thrilling. The setting of the above three roles, from the details, is in line with the causes of the role’s life, personality and so on, and it is reasonable to stage an unexpected wonderful performance.


Strength acting conquers the audience


These three "detectives" can win the hearts of the audience steadily, and the most important thing is their superb acting skills. Pan Yueming contributed a "precise style" in "Chasing the Murder in a White Night", with one person acting in four corners: a cold and mysterious brother, a brother who plays his brother, and a brother who plays his brother. And every one of themThe characters have different temperament and expressions, and they treat the two brothers speciously.


Yan Liang, played in Qin Hao’s Crime without a license, is flamboyant, but also very delicate, with sharp eyes like a beast hunting in the dark, especially when he is staring at the camera to analyze the case, a chill rises from the fundus, thusGet the evaluation of netizens that "squatting in a toilet is a play".


Duan Long, the coldest detective, won the Best Actor at the Tokyo Film Festival for his role as Yu Detective in Blizzard Coming, and the judges said that they hardly considered the second candidate. Duan Long used a series of detailed movements, such as hunching his back and pulling down his huddled leather coat from time to time.Work, all of a sudden the audience back to the 90 s.. It is reported that in the segment of "Model Workers Meet the New Century" that was exposed in the preview, he was praised as a "textbook-level" acting skill by the audience who had seen the film at the film festival because of his excited and trembling face and unreal eyes.


"White Night Chasing Murder" became the overlord of online drama in 2017 with 3.6 billion online broadcasts. Crime without a license scored 8.3 points in Douban. The crime film Blizzard is Coming won the Best Artistic Contribution Award and the Best Actor Award at this year’s Tokyo Film Festival, and it will be released in mainland China on November 17th, which is worth looking forward to.


"Peerless" Guo Fucheng turned into a cash cow, and Zhou Runfa responded to the confession of male fans

1905 movie network news The largest crime blockbuster in history, "Peerless", officially opened its national roadshow on the 25th after its grand premiere in Beijing. Zhou Yun-fat and Guo Fucheng went to all parts of the country to build momentum for the film. Not only did they share all kinds of interesting things about the filming process of the movie "Peerless" with fans around the country, but they also turned into "humanoid cash cows" and gave red envelopes and various benefits to local audiences. Even netizens couldn’t help but sigh: "As expected of the’get rich ‘combination!" There are also netizens who "kindly remind" audiences around the world: "If you have the opportunity, you must hug these two bosses, because then you can be violent (hug) and violent (hug) rich!"

 

Chow Yun-fat and male fans "confess to each other" producer reveals the meaning of the title: Chow Yun-fat is "unparalleled" 


Yesterday, the crime action blockbuster "Peerless", which will be released on September 30, held a special premiere in Hangzhou. Yu Dong, chairperson of Bona Film Group, film producer Huang Bin, and star Zhou Yun-fa and his wife Fa’s sister-in-law appeared in the cinema to take photos with fans.

After watching "Peerless", the audience in Hangzhou said that this well-made, suspenseful, and unexpected crime blockbuster will surely become the most surprising film in this National Day file. When Fa Ge heard the audience’s affirmation in the background, he directly appeared to express his gratitude to the audience, which made the audience overjoyed and madly called Fa Ge and the film. More male fans couldn’t help but "confess" to Fa Ge on the spot: "Fa Ge, I love you!" And Fa Ge, who has always been a "pet fan", also responded kindly: "Dude, I love you too."

On the same day, Brother Fa and producer Huang Bin answered some audience questions on the spot. Some audience members asked Brother Fa why there was such a stunning performance in "Unparalleled", and Brother Fa said bluntly: "Because I love this drama to death, I have filmed so many dramas, and" Unparalleled "is the most enjoyable one for me, so I must complete it in the best state."

There were also audience members who had questions about the title of "Unparalleled". In this regard, the producer Huang Bin answered humorously and tactfully: "Unparalleled means there are no two. Everyone knows that from the past to the present, there is only one Chow Yun-fat, and the movie" Unparalleled "is about him." Huang Bin said that "Unparalleled" is a very different action movie, and I believe it will definitely bring you a stimulating and enjoyable movie viewing experience in this National Day file. "I hope everyone can enjoy the excitement brought by" Unparalleled ", and I hope everyone can recommend this movie more."

 

Guo Fucheng transforms into a "humanoid cash cow" to interpret the role in the film on the spot: Everyone goes to the theater to "watch me change 72"


On the same day, the star Guo Fucheng, Feng Wenjuan and director Zhuang Wenqiang appeared at the Zhengzhou roadshow of the movie "Peerless", instantly igniting the enthusiasm of the audience. In the play, Li Wen, played by Guo Fucheng, is a "human flesh banknote machine". On the same day, he turned into a "human-shaped cash cow", and together with director Zhuang Wenqiang and star Feng Wenjuan, he gave the audience a cash red envelope gift, which brought the atmosphere of the roadshow to a climax. Some audience members sighed: "It turns out that watching" Peerless "can really make a fortune, and there is no one of the strongest koi in October!" Not only is it a cash red envelope, but the three creators also turned into "pet powder maniacs", sending one-stop services such as group photos and intimate contact, which excited fans.

Guo Fucheng, who was at the roadshow, and Li Wen, the submissive and taciturn "Sanwu painter" in the film, looked very charming with a black baseball uniform and tight trousers. Speaking at the scene of him and Fa Ge, Zhang Jingchu and Feng Wenjuan playing eight roles in the film, Guo Fucheng playfully said that he played not only two roles in the film, but dozens of roles in the film. "Because the plot is very exciting, the requirements for the characters are also very high, and it seems that the acting will change 72 times, which is very enjoyable."

Asked about the original intention of starring in the film "Peerless", Guo Fucheng revealed that he was a fan of Director Zhuang. "I have been very fond of Director Zhuang’s works from the beginning, and I am very much looking forward to this kind of cooperation." When asked by an audience if "I took on" Peerless "because of the high salary, Guo Fucheng humorously replied:" The salary I got is all counterfeit money. "A sentence caused the audience to laugh.

With its unique genre of subject matter and brilliant plot design, "Peerless" has received numerous praise in the previous screening venues. Some film critics called the movie "Peerless" the "strongest word of mouth" in advance of the National Day file, and netizens also praised the movie "God Reversal", believing that this is a movie that "you will really understand at the last second".

The movie "Peerless" tells the story of a crime in which a criminal genius "painter" played by Zhou Runfa and a counterfeiting genius played by Guo Fucheng combine two swords to create super dollar bills. The film is directed by Zhuang Wenqiang and produced by Huang Bin. Zhou Runfa, Guo Fucheng, Zhang Jingchu, Feng Wenjuan, Liao Qizhi, Zhou Jiayi, Wang Yaoqing, Fang Zhongxin and other powerful actors co-starred. It will be released nationwide on September 30 and is now fully open for pre-sale.


ATFX foreign exchange science popularization: three data websites that must be known in gold trading

Source: Financial Network
ATFX foreign exchange science: to understand the fundamental trend of crude oil market, we need to pay attention to OPEC and EIA websites, where we can collect the required data; To understand the fundamental trend of the gold market, we need to pay attention to the three websites of world gold council, goldhub and LBMA, where we can also collect the required data. The World Gold Council is the leader of the gold market, and its members are the world’s leading gold mining companies. It describes the characteristics of gold as follows:
1. High liquidity and scarcity;
2. Safe haven in high-risk period;
3. The best choice for hedging risks;
4. Countering the devaluation of legal tender;
These four aspects can be said to include all the functions and attributes of gold. Incidentally, the official website of the World Gold Council is the only one among the well-known websites in the West that I know, which has the quick tools to reprint "Weibo" and "WeChat", so we can see that they attach importance to the China market.
▲ATFX for the picture
Goldhub website is actually a sub-website for storing all kinds of data collected by the Gold Association, and DataGOLDHUB, the menu option in the above picture, is its click entry. The data about the supply, demand and distribution of gold that we want to focus on today are all from the Goldhub website. The reason why the London Gold Market Association is not the key content is that it is not as rich as the World Gold Council, but the website still deserves the daily attention of traders. Next, we will focus on six aspects of gold:
1. The linkage performance of gold price and quotation with other assets.
In this section, we can see all the gold price data since 1970, but we need to register and log in to see the complete content. As China and India are important demand markets for physical gold, this section also introduces the difference between the physical gold prices in China and India and the international dollar gold prices. According to the latest data, the difference between China gold price and international price is $20.54 (discount), and Indian gold price is $2.53 (discount). In addition, this section also shows the quotation and trend curve of the gold futures market, as well as the performance and comparison of gold’s yield in the past year. For example, the yield of gold in the past year was 24.65%, while the yield of global bond market was only 9.20%, the MSCI stock index was 16.93%, and the yield of commodities other than gold was negative 3.08%. It can be seen that gold was the variety with the highest yield in the past year. Of course, if you want to query the daily volatility data of gold or the correlation coefficient between gold and other related investment products, you can find the answer in this section.
2. Gold liquidity
Liquidity usually refers to trading volume, and the greater the trading volume, the better the liquidity; The lower the trading volume, the worse the liquidity. The latest data shows that the daily trading volume of gold is $145.5 billion, which is at a high level. In this sector, you can also see the trading volume of other comparative markets, such as the daily trading volume of corporate bonds in the United States of America is 33.9 billion US dollars, the daily trading volume of gilt bonds in the United Kingdom is 44 billion US dollars, the daily trading volume of S&P 500 is 149.17 billion US dollars, and the trading volume of bonds with one to three years in the United States is 149.68 billion US dollars.
3. Supply and demand
The content of this plate is huge, and it is difficult to summarize it in detail through an article. Here we introduce the key gold supply and demand, and traders interested in the rest of the data can consult the website themselves.
▲ATFX for the picture
It can be seen that there are four main aspects that constitute the demand for gold:
1. Jewelry
2. Technical manufacturing
3. Investment demand
4. Central Bank
Taking the data of 2019 as an example, the jewelry industry consumed 2,122.9 tons of gold, ranking first; Secondly, the investment market consumed 1269.5 tons of gold, ranking second; Once again, the central bank’s gold demand is 668.5 tons, ranking third; The demand for gold in technological manufacturing is the lowest, at 326 tons.
Look at the supply of gold:
▲ATFX for the picture
It can be seen that the supply of gold consists of three aspects: mining, recycling of waste gold and hedging by manufacturers. Among them, the proportion of manufacturer hedging is polar, only -0.7 tons in 2019, so it is directly ignored. In 2019, the total amount of gold mining was 3,530 tons, which was higher than the demand of the jewelry market; The circulating gold is 1281.3 tons, which is higher than the consumption in the investment market.
4. Gold holders and trends
Gold is a physical asset that is highly valued by central banks all over the world, so gold accounts for a large proportion in the central bank reserves of all countries. Many times, the change of the central bank’s total holdings of gold determines the important trend direction of the dollar gold market in the coming year.
▲ATFX for the picture
Looking closely at the above chart, we can see that we have not added the gold holding trend of the Federal Reserve. It is not because the Fed’s gold holdings are not worth mentioning, but because its gold holdings are too large. If it is added to the chart, the trend of other countries will be completely submerged. Here we can explain that the latest gold holdings of the Federal Reserve are 8,133.46 tons, which is much higher than the scale of Russia’s 2,298.65 tons ranked first in the above picture. Although China and India are big consumers of physical gold, their central banks hold only 1,948 tons and 688 tons of gold, which is quite small compared with the United States and Russia.
5. Long-term driving factors of gold
The long-term driving factors of gold come from main categories, including economic expansion, market risk, opportunity cost and trend intensity. There are four main factors that determine the price of gold:
1. Wealth and economic expansion;
2. Market risk and uncertainty;
3. Opportunity cost;
4. Trend strength.
The first two factors play a particularly important role in the long-term performance of gold and form strategic reasons for buying and investing in gold. There is a positive relationship between gold price and economic growth, because gold demand exists in the form of jewelry, technology and long-term savings. This is especially true in developing economies, where gold is often used as a luxury and a means to preserve wealth. Market risk and uncertainty are also related to the long-term performance of gold. Many investors regard gold as the ultimate safe haven-it can effectively hedge against currency depreciation, high inflation and other systemic risks. In addition, other macroeconomic variables, such as interest rates, may increase or decrease the relative cost of holding gold. Price momentum and similar trend variables can further enhance or reduce the performance direction of gold.
6. Short-term driving factors of gold
The short-term here is only the price change of gold in the last month, not the minute and hour level that short-term traders think. In this section, the World Gold Council gives its own short-term driving model of gold, which contains the percentage of influence of various factors on the gold trend. The model in December 2020 shows that economic expansion has contributed 0.26% to the trend of gold; Risk aversion contributed 3.25%; The influence of walking power contributed 2.5%, and we don’t describe the influence of other factors one by one. Interested traders can log in to the World Gold Council official website to check.
ATFX disclaimer:
1. The above analysis only represents the opinion of analysts, and the foreign exchange market is risky, so investment should be cautious.
2. ATFX will not be responsible for any profit or loss that may be caused by using or relying on this information directly or indirectly.
Reporting/feedback

Yuheng Group’s bankruptcy reorganization implicated two pharmaceutical companies Xinbang Pharmaceutical’s acceptance rating watch list.

On the evening of July 8, Xinbang Pharmaceutical announced that Shanghai New Century Rating had put the company on the rating watch list. At present, the company’s main rating is AA.

In the news, Xinbang Pharmaceutical announced on July 7 that the company had received a notice from Harbin Yuheng Group, the concerted action person of Tibet Yuxi, the controlling shareholder. Yuheng Group received the Civil Ruling of Harbin Intermediate People’s Court in Heilongjiang Province, and the court ruled that the creditors of Yuheng Group had accepted the bankruptcy reorganization application of Yuheng Group.

The actual controller of Yuheng Group is Zhu Jiman, who previously became the richest man in Heilongjiang with a wealth of 10.5 billion yuan. Since 2018, the "Yuheng Department" it controlled has fallen into a financial crisis. At present, Yuheng Group controls two listed companies, Xinbang Pharmaceutical and Yuheng Pharmaceutical.

Now, both Xinbang Pharmaceutical and Yuheng Pharmaceutical are facing greater possibility of changes in their controlling rights in the future. From the operational point of view, both listed companies are facing the problem of declining performance.

The former richest company in Heilongjiang Province was repeatedly passively reduced its holdings after being filed for bankruptcy.

On July 8, due to the bankruptcy filed by Yuheng Group, Shanghai New Century Rating listed Xinbang Pharmaceutical with a debt ratio of 52% on the credit watch list.

 

The data shows that at present, the controlling shareholder of Xinbang Pharmaceutical is Tibet Yuxi, which holds 359 million shares of Xinbang Pharmaceutical, accounting for 21.52% of the total share capital of Xinbang Pharmaceutical. Yuheng Group holds 100% equity of Tibet Yuxi and is the concerted action of Tibet Yuxi.

At present, all the shares of Xinbang Pharmaceutical held by Tibet Yuxi have been pledged and frozen by the judiciary. Xinbang Pharmaceutical said that the company is different from Yuheng Group and Tibet Yuxi, and they are independent in business, personnel, assets, institutions and finance. The bankruptcy reorganization of Yuheng Group will not affect the normal operation of the company. Up to now, the company’s production and operation conditions are normal.

Yuheng Group is a Harbin enterprise whose actual controller is Zhu Jiman. In 2017, Zhu Jiman and Bai Lihui were ranked 349th on the Hurun Report with a wealth of 10.5 billion yuan, and they are also the richest people in Harbin.

 

At that time, the most important company in Zhu Jiman’s hands was Yuheng Pharmaceutical. As of July 3, 2020, Yuheng Group held 700 million shares of Yuheng Pharmaceutical, accounting for 32.18% of the company’s total share capital, of which 94.64% had been pledged.

Yuheng Group has been in debt crisis for a long time. In February 2018, the equity of Yuheng Pharmaceutical pledged by Zhu Jiman exploded, and there was a passive reduction at that time.

Since then, the situation of Yuheng Department is even more precarious, and the shares of Yuheng Pharmaceutical held by Heng Group have been put on the judicial auction platform for many times. On July 1, Yuheng Pharmaceutical announced that the equity of Yuheng Pharmaceutical, which Guotai Junan bid through judicial auction in May this year, has been transferred.

On July 7, Yuheng Pharmaceutical announced that the creditors of Yuheng Group applied to Harbin Intermediate People’s Court of Heilongjiang Province for bankruptcy and reorganization of Yuheng Group on the grounds that Yuheng Group could not pay off its debts due and its assets were insufficient to pay off all its debts. The Intermediate People’s Court of Harbin City, Heilongjiang Province accepted the case and ruled as follows: Accept the application of creditors of Yuheng Group for bankruptcy reorganization.

It is worth noting that the transfer of part of the equity of Yuheng Pharmaceutical, which was planned by Yuheng Group for nearly two years, has also been terminated.

According to the announcement of Yuheng Pharmaceutical Co., Ltd., Yuheng Group planned to transfer its 15% equity of Yuheng Pharmaceutical Co., Ltd. in August, 2018. Eventually, due to debt default and judicial freezing of the company’s shares, the share transfer was not successfully implemented. After friendly negotiation between Yuheng Group and the counterparty, the parties signed a Termination Agreement on July 6, 2020, agreeing to terminate the Share Transfer Agreement and related agreements signed on August 17, 2018.

Yuheng Pharmaceutical suffered a huge loss of 2.6 billion last year, and the growth of Xinbang Pharmaceutical declined significantly.

While Yuheng Group was filed for bankruptcy, the operating conditions of Yuheng Pharmaceutical and Xinbang Pharmaceutical actually declined in different ways.

The data shows that Yuheng Pharmaceutical’s net profit declined for three consecutive years. In 2019, its operating income fell by 7.8% year-on-year, with a loss of 2.655 billion yuan. By the end of 2019, Yuheng Pharmaceutical had total assets of 6.4 billion yuan, total liabilities of 4.8 billion yuan and asset-liability ratio of 75%. By the end of 2018, Yuheng Pharmaceutical’s asset-liability ratio was 53%.

In the 2019 annual report of Yuheng Pharmaceutical, it is bluntly stated that "the aging of existing products, shrinking market share and insufficient follow-up reserve products are all unavoidable problems before us."

Yuheng Pharmaceutical proposed at that time to consolidate the traditional pharmaceutical business in 2020, promote the reform of marketing system and focus on building CMO platform. Since the beginning of this year, Yuheng Pharmaceutical has accelerated the disposal of its assets, and the investment income from the disposal of Aonuo Pharmaceutical’s equity in the first quarter was 790 million yuan.

The data shows that in the first quarter of 2020, Yuheng Pharmaceutical’s total operating income was 581 million yuan, down -53.86% year-on-year, and its net profit was 659 million yuan, up 670% year-on-year.

On the other hand, Xinbang Pharmaceutical, a listed company, lost money in the first quarter of this year. Wind data shows that the year-on-year growth rates of operating income of Xinbang Pharmaceutical in 2017, 2018, 2019 and the first quarter of 2020 were 16.3%, 9.63%, 1.14% and -20.22% respectively.

 

From 2017 to the first quarter of 2020, Xinbang Pharmaceutical’s operating income increased year-on-year.

Affected by the COVID-19 epidemic, Xinbang Pharmaceutical was at a loss in the first quarter of this year. During the reporting period, the company’s operating income was 1.246 billion yuan, and the net profit attributable to shareholders of listed companies was 13.016 million yuan, down 121.06% year-on-year. Xinbang Pharmaceutical said that during the reporting period, due to the epidemic, sales revenue decreased compared with the same period of last year, and fixed expenses did not decrease compared with the same period of last year.

For Xinbang Pharmaceutical and Yuheng Pharmaceutical, the bankruptcy of Yuheng Group will also involve the possibility of changes in the actual controller of the company. Both of the above companies said that there is also uncertainty whether the bankruptcy and reorganization of Yuheng Group will lead to changes in the actual control rights of the company.

As of the close of July 8, Yuheng Pharmaceutical’s stock has increased by 22.44% this year, and Xinbang Pharmaceutical’s stock has decreased by 7.8% this year. The total market value of the two companies corresponds to 8.155 billion yuan and 8.069 billion yuan respectively.

Beijing News Shell Finance Reporter Li Yunqi Editor Xu Chaoproofread Lin Zhao

Yuan Qingmao attended the 2021 Bamboo Leaf Industry Strategic Development Conference.

On December 19th, the 2021 Bamboo Leaf Industry Strategic Development Conference with the theme of "Healthy Tide Rising, Bamboo Dreams Flying" was held in Taiyuan. Yuan Qingmao, Party Secretary and Chairman of Fenjiu, attended the meeting and delivered a speech. Tan Zhongbao, General Manager of Fenjiu, delivered a speech. Company leaders Gao Zhiwu, Yang Bo, Yang Jianfeng, Chang Jianwei, Liu Weihua, Gao Ming and Zhang Chunsheng attended the conference, and the national Zhuyeqing dealers and cross-border partners listened to the conference in an "online+offline" way.

Yuan Qingmao, Party Secretary and Chairman of Fenjiu

Tan Zhongbao, general manager of Fenjiu

At the conference, Yuan Qingmao made a speech entitled "Healthy Tide Rising, Taking Advantage of the Situation, Strive to Build a Bamboo Leaf Green Health Industry Cluster with Shanxi Characteristics". First, on behalf of Fenjiu Group, he thanked the dealers, partners and employees of Bamboo Leaf Green in the front line of the market for their hard work in the past year, and affirmed the excellent performance of Bamboo Leaf Green Industry Company in the past year with the words "Stand tall, do new things, find accurate and get together".

The first word is "stand tall". In the report of the 12th Party Congress of Shanxi Province, Secretary Lin Wu regards the big health industry as one of the strategic emerging industries in Shanxi, with the goal of realizing the cluster development of 100 billion scale. Putting Zhu Yeqing in the high position of the big health industry from the top-level design is highly consistent with the internal requirements of promoting high-quality development in all directions and the high-quality development layout of Shanxi’s new kinetic energy for future economic development. This is the fundamental starting point and foothold for Zhu Yeqing to deeply grasp the development opportunities.

The second word is "doing new". On the one hand, based on the underlying logic of scientific and technological innovation, Xin is constantly innovating technologies such as extraction and preparation, and upgrading products. On the other hand, we are constantly promoting the integration of production, supply, marketing and research, and gradually building a new supply chain based on the wine industry chain and integrating the wine industry chain and the health industry chain, so as to gain the empowerment of health-related industries more quickly.

The third word is "accurate". Zhuyeqing has found a unique position in the market. From the famous history of more than 1500 years, from the two intangible skills of Fenjiu brewing technology and Zhuyeqing brewing technology, from eight national patents, the brand positioning of "healthy national wine" has been condensed. A brand has excellent quality, profound cultural heritage and unique health value, so it can be said that the imagination is infinite.

The fourth word is "get together properly". Zhu Yeqing can achieve today’s achievements precisely because he put the concept of "win-win" in a prominent position and regarded the dealer’s difficulties as his own, which won the full support of dealers and partners all over the country. I believe that with an open mind and tenacious efforts, there is no difficulty that can’t be overcome, and there is no cause that can’t be developed.

Yuan Qingmao pointed out that in the next step, the bamboo and green health industry should achieve "a higher level" in five aspects.

First, a higher position, to create a characteristic health industry cluster in Shanxi

Shanxi is one of the most suitable provinces to develop large-scale health industry in China. There are three main points: First, our province is rich in traditional Chinese medicine culture, rich in Chinese herbal medicine resources and has a solid foundation for health industry. Second, our province pays close attention to industrial transformation, and deeply implements the 100 billion industrial cultivation project, one of which is to build a 100 billion-level big health industry, which is supported by good policies. Third, with the great planning and construction in the province, a large number of approved tourism and rehabilitation projects have been cultivated and are being upgraded, which has the demand for cluster development. We should further improve our position, plan the future with a higher vision, put the development of bamboo leaf green big health industry in the policy orientation of the country and Shanxi in the development of big health industry, actively integrate into the overall development of the province, seize the opportunity, and accelerate the integration process of bamboo leaf green production, supply, marketing and research. At the same time, actively seek cooperation opportunities in the health industry chain in the upstream and downstream, attract high-quality partners in health-related fields, and jointly build a bamboo leaf green health industrial cluster with Shanxi characteristics.

Second, deepen reform and strive to be the "vanguard" of deepening reform of state-owned enterprises

On December 16th and 17th, at the economic work conference held by Shanxi Provincial Committee, it was proposed that state-owned enterprises should practice their internal strength. At present, the volume of bamboo leaf is not large enough, but it just brings huge space for deepening reform. Zhuyeqing Industrial Company has set up a marketing team with young and highly educated talents as the main force, and made great strides in market-oriented innovation in organization and mechanism, which is the advantage of Zhuyeqing’s deepening reform. The reform and innovation of Zhuyeqing should constantly improve the modern enterprise system and market-oriented operation mechanism, focusing on deepening market-oriented reform in management, employment and incentives, especially on the mechanism of leading people, inspiring people and supporting people, so that young people of Zhuyeqing can fully release their passions and dreams and make youthful vitality the strongest driving force for the development of Zhuyeqing’s big health industry.

Third, more accurate positioning, grasping consumer demand and seizing the mind

Zhu Yeqing should grasp the potential of policy and reform, but also the visible demand and the invisible "mind". No matter in any cycle or stage, where the demand is, the market is there. At present, the rise of new consumption lies in meeting people’s needs and yearning for a better life. Who can meet the real needs of consumers, satisfy their mental demands and provide higher quality services, who can master the password of development. At present, the consumption trend is alternating between the old and the new, and the market is at the key node of "good money drives out bad money". We should continue to pay close attention to the market demand, adhere to the development orientation of medium and high-grade wine, make refined products and services, continue to respond to the changing consumer’s mental demands, pay attention to the opportunities stimulated by the two-way interaction between the supply side and the demand side, and work with the majority of dealers to provide products and services with higher quality, better demand and better experience.

Fourth, live a more active culture and plant a natural and healthy cultural foundation.

Both bamboo leaf green and Fenjiu have a very profound cultural background, which is an invaluable asset left by our ancestors. However, the profound culture must be transformed into brand value and market competitiveness, in order to live up to everyone’s great expectations of Zhu Yeqing. We should adhere to the cultural guidance, dig deep into the cultural connotation, make the culture of Zhu Yeqing come alive, tell the story of Zhu Yeqing well, and think about how the healthy cultural core of "harmony between man and nature" is displayed, spread and deeply rooted in people’s hearts. It is necessary to further upgrade from product sales thinking to cultural marketing thinking, develop a healthy cultural communication system with rich experience, and make consumers fall in love with natural and healthy bamboo leaf green products and services through the creation of fresh experience, thus planting the cultural foundation and consumption foundation of bamboo leaf green health.

Fifth, strengthen party building and adhere to party building to lead transformation and upgrading.

Upholding the Party’s leadership and strengthening Party building are the "roots" and "souls" of state-owned enterprises. At present, Zhuyeqing is transforming and upgrading from a wine industry to a big health industry. This is not only an economic issue, but also a political issue, and it is a political responsibility and concrete action to implement the goal of "promoting high-quality development in all directions". The Party Committee of Zhuyeqing Industrial Company should adhere to the unity of strengthening party leadership and improving corporate governance, deepen the integration and development of party building work with production and marketing, and build a strong fighting fortress for grassroots party organizations in the front line of market, production and scientific research. At the same time, it is necessary to strengthen the construction of cadres, face the vast number of young employees, build a good talent training system for the health industry, and provide strong support for the sustainable development of Zhuyeqing’s big health industry.

Yuan Qingmao said that under the strong leadership and cordial care of the provincial party committee and the provincial government, Fenjiu Group will firmly seize the great opportunity of Shanxi to build a 100 billion-level health industry, with a higher position, deeper reform, more accurate positioning, more lively culture and stronger party building, and innovate to open up a big market for the upgrading of bamboo and green health consumption. Zhuyeqing Great Health Industry will also work with distributors and partners all over the country to strengthen the brand value of Zhuyeqing, broaden the new path of Zhuyeqing Industry, and create a Zhuyeqing Health Cluster, so as to start a new journey of promoting high-quality development in Shanxi in all directions, and then show new achievements and responsibilities.

Tan Zhongbao addressed the conference, saying that 2021 is the first year of the "14th Five-Year Plan" of Fenjiu Group, and it is also the most critical and landmark year for the development of Zhuyeqing brand.

In the past year, Zhuyeqing Industrial Co., Ltd. dared to try and explore, practiced the strategic plan of "healthy national wine", and fully relied on the two dominant genes of "national brand" and "herbal health" to help the high-end positioning of Zhuyeqing brand and create a younger brand image. It has broadened new promotion channels, boosted the brand value of Zhuyeqing, expanded the consumption boundary of dew wine category, created excellent sales performance and created a brand-new development path. Looking back, there are both achievements and regrets; Based on the current situation, there are both pressures and opportunities; Looking forward to the future, there is both motivation and confidence.

The development of Zhuyeqing liquor has a broad prospect and a long way to go. No matter when, our goal of building Zhuyeqing Liquor into a "healthy national wine" will not waver. Our goal of making fine wine for consumers and making it a "necessity for a better life" will not waver. Our goal of working together with our partners and sharing development results will not waver. Let’s work together to make full efforts to achieve a strong return of the brand value of Zhuyeqing Liquor with a big pattern, a big hand and a big mind. Facing the future, Zhuyeqing will join hands with dealers to unite the strength of the general trend of industrial development, the strength of the wave of innovation and the strength of living culture inheritance, and jointly open up a beautiful picture of "health always exists and bamboo leaves last forever".

Gao Zhiwu, Secretary of Fenjiu Discipline Inspection Commission and Ombudsman

At this conference, Gao Zhiwu announced the commendation decision for the outstanding national distributors and partners of Zhuyeqing in 2021. The leaders of the group company presented awards to the winners, and representatives of the winning distributors and outstanding provincial managers spoke.

Yang Bo, member and director of Fenjiu Party Committee and executive director of Zhuyeqing Industrial Company.

Yang Bo made a report on the development of bamboo leaf green. In the report, the future development path of Zhuyeqing was made "three publicity": first, the business model of Zhuyeqing was publicized, that is, "one program is the mission, four essences are the culture, and three magic weapons are the new way", and the new development concept was fully implemented to build a large health industrial cluster with Shanxi characteristics led by the brand of Zhuyeqing; The second is to publicize the layout of Zhuyeqing next year, deepen the innovation and coordination of "traditional plate+innovative plate", and comprehensively expand the southern markets such as South China and East China; The third is to open the customized service of Zhuyeqing. Zhuyeqing has set up the "Qingxiang Innovation Center" to provide "five customized" services such as marketing model, human resources, membership system and cultural products for middle and high-end partners.

Yang Jianfeng, Deputy General Manager of Fenjiu

The meeting was presided over by Yang Jianfeng, deputy general manager of Fenjiu.

Qu Xiangdong, chairman of Xingzhi Exploration Culture Development Group and founder of Xuanzang Road brand, spoke as a special guest of the conference and awarded the flag to the "Zhuyeqingge 17 Team". Zhuyeqing will continue to invite consumers, distributors and partners from all over the country to embark on the journey of reinventing themselves in the Gobi desert and pursue the noble pursuit of empowering life.

Ping An Group Ping An Health signed a framework cooperation agreement with Zhuyeqing Industrial Company. Ping An Health focuses on the "insurance+service" model, and like Zhuyeqing, it is gradually transforming and upgrading from product sales to "product+service" model. The two sides will jointly explore the embedded membership service for the middle and high-end circle, and innovate and expand the new cross-border mode to serve the needs of a better and healthy life.

Through the brand positioning of Zhuyeqing’s "healthy national wine" and the creation of high-end products, coupled with the cross-border integration of health service resources, it has inspired the participation of partners in various fields across the country. Country Garden Service Group, Beijing Zhongke Xin Business, Shengshi Datang Investment Group, Shenzhen Baida Health and other enterprises signed contracts with Zhuyeqing Industrial Company at the conference site.

After the meeting, Yuan Qingmao, Tan Zhongbao and other company leaders took a group photo with the dealers.

"In the Blizzard" exposure stills Leo Angel love atmosphere full marks.


1905 movie network news Starring in the TV series "In Blizzard Time" and releasing the first encounter stills of falling snow. The dim street lamp shines a dreamy spot, and the snow is falling outside the window. In the snow, Wu Lei’s shoulder bag is fully armed. Angel leaned against the retro doorframe, making a phone call in the dim light, and the sweet atmosphere spread warmly in the blizzard.


Adapted from the novel of the same name, this drama is another film-and-television work by writer Mo Bao Feibao following the works such as Why Shengxiao Mo, Zhou Sheng as usual, etc. It tells the youth love story of retired talented snooker player Lin Yiyang (Leo) and popular nine-ball star Yin Guo (Angel). The two met on the night of a rare snowstorm in ten years. With the help of Yin Guo’s cousin, they gradually became familiar with each other and began to work together for billiards and love.


It is reported that the film is currently being filmed in Finland.


Future "chain love" | blockchain rises to the height of national strategy

In 2018 and 2019, the blockchain gained unprecedented attention in policy, and officially rose to the national strategic level in 2019, which also made domestic blockchain practitioners more confident.A blockchain professional popular science reading "Love with the Future-Entering the Blockchain Kingdom" compiled by the Securities Daily Financial Institutions Center takes you back to the two blockchain policy years of 2018 and 2019. And from a policy point of view, why the blockchain is so "valued".
In the new era, especially in 2018-2019, as a new generation of information technology, blockchain began to increasingly enter the strategic decision-making vision of decision-makers in China. The following facts are the best examples and manifestations.
The National 13th Five-Year Plan for Informatization, the 13th Five-Year Plan for the Development of Information Technology in China’s Financial Industry, the blockchain white paper issued by the Ministry of Industry and Information Technology and the Industrial Internet Development Action Plan (2018-2020) have appeared one after another.
On February 18, 2019, People’s Daily, the official newspaper of the Central Committee of the Communist Party of China, published a reporter’s article "Enhancing the Ability of Scientific and Technological Innovation-Grasping the Important Strategic Opportunity for China’s Development" in an important position on the front page. The article points out that "a new generation of information technology, represented by artificial intelligence, quantum information, mobile communication, Internet of Things and blockchain, is accelerating its breakthrough application … A new round of scientific and technological revolution and industrial transformation is reconstructing the global innovation landscape and reshaping the global economic structure".
期间,还有两件重要大事要强调:一是2018年5月28日,习总书记在中国科学院第十九次院士大会、中国工程院第十四次院士大会上发表重要讲话,明确地将区块链与人工智能、量子信息、移动通信、物联网一道列为新一代信息技术的代表。二是2019年8月18日,中共中央、国务院印发的《关于支持深圳建设中国特色社会主义先行示范区的意见》中明确提出,要支持在深圳开展数字货币研究与移动支付等创新应用。
10月24日,本来是个普通的日子,但从历史上看,又不是普通的一天。
10月24日,是每年一度的“联合国日”。同时我们竟然还发现这一天还是一个非常有趣、少有人知、又存在无数“梗”的“程序员节日”。
2019年的这一天,对中国区块链行业的发展来说,更有了新的时代意义:区块链从这一天开始正式上升为中国的国家战略:区块链成为中国核心技术自主创新的重要突破口。
10月24日当天,星期四,下午中共中央政治局就区块链技术发展现状和趋势进行了第十八次集体学习。中共中央总书记最高领袖在主持学习时强调,区块链技术的集成应用在新的技术革新和产业变革中起着重要作用。我们要把区块链作为核心技术自主创新的重要突破口,明确主攻方向,加大投入力度,着力攻克一批关键核心技术,加快推动区块链技术和产业创新发展。
会上,最高领袖强调,要强化基础研究,提升原始创新能力,努力让我国在区块链这个新兴领域走在理论最前沿、占据创新制高点、取得产业新优势。总书记在此用“最”“高”“新”三个字向全国人民提出了区块链发展的高标准和严要求。总书记同时还提出了“区块链+”的概念,明确提出三大融合,即加快区块链和人工智能、大数据、物联网等前沿信息技术的深度融合,与实体经济的融合以及与民生领域的融合。习总书记提出的加强基础技术研究、行业应用落地以及与科技、经济和社会深度融合等观点,无疑对中国区块链行业的未来发展和创新突破方向,给出了十分清晰的回答。
At this important meeting, Chen Chun, a professor at Zhejiang University and an academician of China Academy of Engineering, gave a related explanation on blockchain. The next day, on October 25, Xinhua News Agency released a major report on "Accelerating the Development of Blockchain Technology and Industrial Innovation". On the evening of October 25, CCTV broadcasted the speech of the Supreme Leader General Secretary on the blockchain technology industry, deeply touching the essence of the industry and the status quo, opportunities and breakthrough points of the blockchain for 5 minutes and 29 seconds. In fact, this is not surprising, and it is not difficult to understand. On the contrary, it makes people awake and suddenly enlightened.
Spring River Plumbing Duck Prophet.As a leading indicator of society, the stock market took the lead in making a strong response. The Chinese concept stocks in the American stock market could not bear loneliness as soon as they opened, and rose strongly.Among them, after the release of Xinhua News Agency, xnet, which was in a loss state, rose 107.76% to close at 4.820 US dollars at 16: 00 EST on October 25th. The company’s website shows that this is a company that provides services such as intelligent contract development, blockchain application landing, blockchain business ecological construction, and touches all walks of life including physical industry, artificial intelligence, Internet of Things, and life sciences. Other related concept stocks also rose well, such as the ninth city.
In the domestic stock market, since October 25th is Friday, this news reached its climax on October 28th (Monday) after a weekend of "blockchain".For the performance of A-shares on that day, a report in Securities Daily said, "How many blockchain companies have a daily limit of more than 100?" ",widely reprinted and quoted by major websites and industry insiders. The article said, "On October 28, the blockchain became a popular star in the capital market. As of the close of the day, various capitals in Shanghai and Shenzhen stock markets poured in, and more than 100 blockchain concept stocks had daily limit. At the same time, the problem of blockchain on the investor interaction platform has exploded. On October 28th alone, on the interactive platform of Shenzhen Stock Exchange, there were more than 1,000 interactive questions and answers about blockchain, exceeding the sum of the first half of the year. The article also said that the number of blockchain concept stocks doubled overnight, from more than 80 stocks to more than 170. Unfortunately, at present, only a few listed companies such as Far Light Software, Accurate Information and Easy-to-See Shares have actual income from blockchain projects.
On November 18, 2019, CCTV’s 13 sets of Focus Interview broadcasted a file "Blockchain is not a" withdrawal chain ",which generally reflected the real situation of the domestic blockchain market. In the program, Wu Zhen of the Key Laboratory of Internet Finance Security Technology of the National Internet Emergency Center disclosed in an interview that there are currently more than 30,000 enterprises related to blockchain in China, but less than 10% of enterprises actually own blockchain technology. Most enterprises only take advantage of the situation or create momentum, and some even implement various tricks.
At this meeting, although everyone knows that Academician Chen Chun explained the blockchain, because there is no detailed report, it is basically unclear what he specifically said. So someone "dug up" the content of his speech at the 2019CCF Blockchain Technology Conference held in Chengdu on October 12 that year. After all, this speech is closest to October 24th.At the Chengdu Conference, the topic of Chen Chun’s speech was "Key Technologies of Alliance Blockchain and Regulatory Challenges of Blockchain". He said that China has a global advantage in the construction of the underlying platform of the alliance chain, and the alliance chain is the main force for the future development of blockchain. The research focus of blockchain technology in China will focus on the key technologies of alliance blockchain and blockchain supervision, and it is suggested that the technology of data collaboration between the chain and the chain should be the next development direction.
Therefore, many people in China believe that it is possible for China to develop only alliance chains and promote the innovative development of such technologies.In this regard, Li Guang Gan, a researcher at the State Council Development Research Center, has his own unique views. He said that there are many types of blockchain, and different applications are very different. The alliance chain is not complicated, the most complicated is the public chain. The underlying architecture of the public chain is complex and requires higher requirements. If we only focus on the alliance chain, it seems that there is a great deficiency. He further explained that why should China emphasize the path and direction of public chain and alliance chain technology? This may be related to a policy background, that is, in 2017, the People’s Bank of China, together with several ministries and commissions, issued a special document to restrict the trading of encrypted digital coins and the issuance of tokens. Because the public chain has the characteristics of "issuing money", the alliance chain can have money or no money. It is understandable that the development of public chain is limited under this background.
"Chain Love with the Future: Entering the Blockchain Kingdom" by Ma Fangye Zhang Zhiwei Xu Tianxiao, published by China Financial and Economic Publishing House in June 2020.
"This article is taken from Love with the Future Chain-Entering the Blockchain Kingdom. Please pay attention to this book for more details. The book was edited by Ma Fangye, deputy editor-in-chief of Securities Daily, and was written by Zhang Zhiwei, Xu Tianxiao, Xing Meng, Li Bing, Wang Ning, Lv Dong, Su Xiangyu, Peng Yan and Yu Junyi, the central department of financial institutions of Securities Daily. Recently, it was officially published by China Financial and Economic Publishing House. "
Editor: Xing Meng On Duty Editor: Huang Xiaoqin
Final review: Ma Fangye/Zhang Zhiwei
Reporting/feedback

Jiangsu: Freshmen ride 300 kilometers to report to the university.

       Cctv newsRecently, Yangzhou Industrial Vocational and Technical College in Jiangsu welcomed more than 5,000 freshmen, including Li Zishi, a freshman from Lianyungang, who rode more than 300 kilometers to report to the school from his hometown.

       Li Zishi told reporters that from the moment he received the admission notice, he planned to report to the university by bike. During the summer vacation, Li Zishi worked out a detailed cycling route.

       Before leaving, Li Zishi delivered the luggage to the school by courier and went into battle lightly. He rode all the way according to the planned route, and when he was tired, he stopped at the side of the road to rest. In this way, Li Zishi took three days and successfully arrived in Yangzhou after riding more than 300 kilometers.

       Li Zishi said that he is 18 years old. Riding to the campus is an "adult gift" for him. In the next college career, he will continue to carry forward the "riding" spirit of courageously marching forward and completing his studies.

Scientists in China "portrait" the cells of 15 kinds of tumors.

  Xinhua News Agency, Beijing, February 7 (Reporter Lin Miaomiao, Xia Ke) Different types of cancer have different cell compositions, which leads to different characteristics in the occurrence and development of tumors. Recently, scientists in China systematically described the characteristics of tumor infiltrating myeloid cells in 15 kinds of cancers, including gastric cancer, colorectal cancer, liver cancer, lung cancer and breast cancer, from the single cell level.

  This research paper, which was co-operated by Ji Jiafu team of Peking University Cancer Hospital and Zhang Zemin research group of Peking University Biomedical Frontier Innovation Center, was recently published in the international academic journal Cell.

  The research team compared the characteristics of myeloid cell groups such as mast cells, dendritic cells and tumor-associated macrophages in different cancer species, which provided an important basis for immunotherapy targeting myeloid cells in different cancer species.

  According to reports, tumors have a complex ecosystem, and cancer cells form a complex cell regulatory network by interacting with many other types of cells. Among them, myeloid cells play an important role in regulating tumor inflammatory response and angiogenesis, so they have become another popular target cell in clinical research of cancer treatment after lymphocytes.

  China is a country with high incidence of gastric cancer. Scientists have found that the proportion of mast cells in tumor tissues of gastric cancer is higher than that in normal tissues adjacent to cancer, indicating that the accumulation of mast cells in tumor tissues plays an important role in the occurrence and progress of gastric cancer. There are macrophage groups in gastric cancer tissues that up-regulate angiogenesis-related signal pathways, indicating that macrophage groups play an important role in gastric cancer tumor microenvironment.

  By further integrating the single-cell transcriptome sequencing data produced by the team and published public data, the research team constructed the myeloid cell maps of 15 cancer species, including gastric cancer, and systematically compared the similarities and differences in composition, development and function of each myeloid cell group among different cancer species.

  It is found that mast cells present different functional states in various cancer species, and there are macrophage groups that up-regulate the signal pathway related to angiogenesis in different types of cancer. Macrophages are highly heterogeneous in different cancer species, which means that it is especially necessary to consider their transcription specificity in different cancer species when carrying out immunotherapy for macrophages.