▍ Source: Announcement of Pharmaceutical Companies

▍ Finishing: Cypress Blue-Corn

▍ Industry concentration has been further improved.

In 2019, there were frequent mergers and acquisitions between pharmaceutical companies. Observing these cases, we can find that some of them spun off their subsidiaries and some strengthened their own strengths through acquisitions. In addition, the sale of non-core assets by foreign pharmaceutical companies and the takeover by domestic pharmaceutical companies have also caused industry analysis.

In these cases, some of them have been completed and some are still in progress. Through the inventory of one-year acquisition cases, it seems that the industry is progressing in the direction of increasing concentration.

With the deepening of medical reform, the implementation of policies such as consistency evaluation, quantity procurement and DRG, and the improvement of industry access threshold, SMEs will be acquired more frequently by large enterprises.

Of course, this is just like the plan of "supporting the merger and reorganization of pharmaceutical production enterprises, cultivating a number of large enterprise groups with international competitiveness, and improving the concentration of pharmaceutical industry" in the "Several Opinions on Further Reforming and Improving the Policy of Drug Production, Circulation and Use" issued by the State Council in early 2017.

Suzhou Novartis completed the sale.

On December 21st, Zhejiang Jiuzhou Pharmaceutical Co., Ltd. issued the Announcement on Completion of 100% Equity Delivery of Suzhou Novartis Pharmaceutical Technology Co., Ltd., and formally merged Suzhou Novartis into its subsidiary.

Jiuzhou Pharmaceutical announced on November 30 that the board of directors passed the Proposal on Foreign Investment to Buy 100% Equity of Suzhou Novartis Pharmaceutical Technology Co., Ltd., and estimated to buy 100% equity of Suzhou Novartis held by Novartis Investment with self-raised funds of about 790 million yuan.

According to the data, Suzhou Novartis acquired by Jiuzhou Pharmaceutical Co., Ltd. mainly consists of factory buildings, production lines, process equipment, etc. after divesting the technology and drug development assets held by Novartis.

Fosun Pharma sells assets for 3.6 billion yuan

On December 19th, Shanghai Fosun Pharma (Group) Co., Ltd. issued the Announcement on the Progress of Selling Assets and Foreign Investment, intending to transfer all the limited partnership interests of Healthy Harmony Holdings, L.P. (whose main assets are "United Family" hospitals and clinics) and the management partner of Healthy Harmony Holdings, L.P.. The consideration for this transfer is about US$ 523.15 million (equivalent to about RMB 3.6 billion).

Tasly sells Tasly Medicine Marketing Group.

On December 17th, Tasly announced that it had signed the Framework Agreement with Chongqing Pharmaceutical, and made an agreement on selling the equity of its holding subsidiary Tianjin Tasly Pharmaceutical Marketing Group.

According to the Framework Agreement, Chongqing Pharmaceutical intends to acquire 87.47% of the shares directly and indirectly held by the company and the shares held by other shareholders of Tianshi Marketing by paying cash consideration.

Nanjing pharmaceutical holding enhua herun

On December 13th, Nanjing Pharmaceutical Co., Ltd. issued the Announcement on Completion of Change Registration Procedures for Acquisition of Equity, indicating that the acquisition of Jiangsu Enhua Herun Pharmaceutical Co., Ltd. for 72.24 million yuan has completed the change registration procedures for shareholders and legal representatives. So far, Nanjing Pharmaceutical directly holds 70% equity of Enhua Herun.

China Resources Sanjiu acquires Aonuo Pharmaceutical.

On November 27th, China Resources Sanjiu Pharmaceutical Co., Ltd. issued the Announcement on Acquisition of 100% Equity of Aonuo (China) Pharmaceutical Co., Ltd., and planned to acquire 100% equity of Aonuo (China) Pharmaceutical Co., Ltd. held by Yuheng Pharmaceutical for 1.42 billion yuan.

According to the announcement, the core products of Aonuo Pharmaceutical are calcium zinc gluconate oral solution, vitamin C chewable tablets and Shenzhi Dendrobium granules, and its "Aonuo" and "Jinxin Jinjiute" are well-known brands for children to supplement calcium. China Resources Sanjiu said that the acquisition can improve the category layout of self-diagnosis and treatment (CHC), which can be organically combined with the advantages of China Resources Sanjiu in consumer insight, brand operation and terminal coverage.

Pfizer merged with Mylan.

On November 12th, Mylan and Pfizer officially announced the name of the new company-Via Tris, which was formed by the merger of Mylan and Pfizer’s subsidiary Pfizer Puqiang.

The 2018 financial report shows that Pfizer’s global revenue is $12.5 billion, and the China market contributes $2.4 billion. Mylan is a multinational giant, with a global revenue of 11.434 billion US dollars in 2018, and has not yet started business in China.

Da Shen Lin bought 123 chain pharmacies.

On November 7, Dashenlin Pharmaceutical Group Co., Ltd. issued the Announcement on Acquisition of 51% Equity of Nantong Jianghai Pharmacy Chain Co., Ltd., and plans to acquire 51% equity of Nantong Jianghai Pharmacy Chain Co., Ltd., with the target company including 123 chain pharmacies and the acquisition amount of 120 million yuan.

GSK sells Suzhou factory and Hepudin.

On July 8, Fosun Pharma announced that its holding subsidiary, Chongqing Yaoyou Pharmaceutical Co., Ltd., intends to acquire 100% equity of GlaxoSmithKline Pharmaceutical (Suzhou) Co., Ltd. for no more than RMB 250 million. If the transfer is completed, it will hold the drug registration approval of lamivudine tablets (specification: 0.1g) for the treatment of chronic hepatitis B and the production license and GMP certificate of its production facilities.

On July 9th, GSK China confirmed to Cyberland that both parties expected the transaction to be completed by the end of November.

Sinopharm Holdings acquired Anhui Pharmaceutical Group

On May 8, the official public platform of Sinopharm Holding Anhui Co., Ltd. released a message: Sinopharm Holdings officially signed a contract to acquire Anhui Pharmaceutical Group. According to public information, Anhui Pharmaceutical Group is a large-scale commercial circulation enterprise approved by the Anhui provincial government in December 2002.

China Resources Medicine Acquires Jiangzhong

On April 17, Jiangzhong Pharmaceutical Co., Ltd. announced that the company recently received a notice from the controlling shareholder of the company. With the approval of Jiangxi Provincial Market Supervision Administration, the controlling shareholder completed the industrial and commercial change registration of the enterprise name and business scope on April 8, 2019.

After the change, Jiangxi Jiangzhong Pharmaceutical (Group) Co., Ltd. was changed to China Resources Jiangzhong Pharmaceutical Group Co., Ltd. Jiangzhong Pharmaceutical said in its 2018 annual report that the brand value of "Jiangzhong" was 20.715 billion yuan, ranking 231st among the top 500 Chinese brands and 6th in the pharmaceutical industry. For China Resources Medicine, the acquisition of Jiangzhong Group won brands such as "Jiangzhong" and "Chuyuan".

Bristol-Myers Squibb acquires Xinji.

On January 3rd, Bristol-Myers Squibb announced a $74 billion acquisition of Xinji. According to the agreement between the two parties, Bristol-Myers Squibb will acquire Xinji Company in the form of $74 billion in cash and stock transactions to build a first-class biopharmaceutical giant that can compete with the world’s largest pharmaceutical manufacturer.

In fact, the merger and acquisition of pharmaceutical companies in 2019 is far more than that. By combing the actions of well-known enterprises, the purpose is to find the trend of industry changes under these mergers and acquisitions. In addition, in the announcements of many listed pharmaceutical companies selling assets this year, many properties were thrown out. Some analysts believe that pharmaceutical companies sell houses to survive, but a more rational view should be due to the limited value-added space of real estate.

　　At least 1,500 people were killed in the conflict, and Saakashvili said that Russia and Georgia entered a state of war.

In South Ossetia, a Georgian tank was hit and burst into flames. This edition of photos was issued by Xinhua News Agency.

On the 9th, Georgia declared a "state of war".

Georgian soldiers ran past a building that caught fire after being attacked.

　　The conflict in South Ossetia, Georgia escalated on the 9th. The Russian military announced on the same day that it had taken control of Tskhinvali, which Georgia claimed to control the day before. Georgia declared a "state of war" on the 9th. Georgian President Saakashvili said that Russia "invaded Georgia without scruple". Although the two countries did not declare war, they actually entered a state of war.

　　At least 1,500 people have died in South Ossetia as of the 9th, and more than 30,000 refugees have flooded into Russia. US President Bush called for a ceasefire between the two sides.

　　situation on the battlefield

　　Russian troops killed and injured more than 100 people.

　　The conflict in South Ossetia, Georgia, continued on the 9th. Russian peacekeepers who entered South Ossetia took control of Tskhinvali that day. The Georgian side has not confirmed this statement. Anatoly Nagovitsyn, Deputy Chief of Staff of the Russian Armed Forces, said on the 9th that two Russian warplanes were shot down.

　　This is the first time that Russia has admitted that the fighter plane was shot down. Georgia claimed on the same day that it shot down 10 Russian warplanes and destroyed 30 tanks.

　　Igor Konashenkov, Assistant Commander-in-Chief of the Russian Army, said that the number of peacekeepers killed in Russia rose to 15 on the 9th, and 150 were injured. It is unclear how many soldiers and equipment the two sides have invested.

　　respond

　　Ge recalled troops in Iraq

　　Georgian President mikhail saakashvili said on the 9th: "I signed a decree declaring the country into a state of war". Alexander Lomaya, secretary of Georgia’s National Security Council, later said that the Georgian parliament unanimously passed the order signed by Saakashvili on the same day, announcing that the country had entered a state of martial law for 15 days.

　　On the 9th, the Georgian government evacuated the staff in the Presidential Palace and other office buildings to guard against air strikes by Russian warplanes.

　　Bondo Maisuradze, commander of Georgian troops in Iraq, said on the 9th that Georgia plans to withdraw all its troops in Iraq and transfer them all to South Ossetia.

　　Maisuradze said: "All Georgian troops (in Iraq) should leave." He said that the specific withdrawal plan has not yet been finalized, and Georgia has asked the United States for assistance. Earlier, Saakashvili said in an interview with the media that he began to withdraw troops stationed in Iraq on the 9 th. There are 2000 Georgian troops in Iraq.

　　progress

　　Russia wants to send more troops to promote peace

　　Russian President Dmitry Medvedev convened Defense Minister Anatoly serdyukov and Armed Forces Chief of Staff Nikolai makarov to discuss the situation in South Ossetia on the 9th. Medvedev said: "Russian peacekeepers and reinforcements are now taking action to force Georgia to (agree to restore) peace." Russian Foreign Minister Sergei Lavrov said that "the situation in South Ossetia continues to deteriorate" and has now suffered a "humanitarian disaster". He said that about 1,500 people in South Ossetia died in the conflict, and the death toll continues to rise.

　　Itar-Tass quoted sergey sobyanin, director of the Russian Prime Minister’s Office, as saying: "More than 30,000 refugees have poured into Russia in the past 36 hours."

　　■ Link

　　China calls on all parties to the conflict to cease fire.

　　China’s Foreign Ministry spokesman Qin Gang said on the 9th that China is seriously concerned about the escalation of tension and armed conflict in South Ossetia. China calls on relevant parties to exercise restraint and cease fire immediately. Qin Gang said: We sincerely hope that all parties to the conflict can resolve their disputes peacefully through dialogue, so as to maintain peace and stability in the region.

　　US President Bush, who is in Beijing, said on the evening of 9th that the armed conflict in South Ossetia has affected the peace of the whole region. He called on all parties to cease fire immediately and return to the position before August 6.

　　The United Nations Security Council met on the 8th to discuss the conflict in South Ossetia, but the 15 members failed to reach an agreement. This is the second meeting of the Security Council in the past two days to discuss this issue.

　　analyse

　　The United States and Russia wrestle over South Ossetia.

　　Georgian President Saakashvili has been pursuing the policy of actively integrating into the West and joining NATO since he took office. This policy is strongly supported by the United States.

　　After Kosovo declared independence in February this year, Russia began to adjust its policy toward South Ossetia in order to counter the US position of recognizing Kosovo’s independence. On March 21, the Russian State Duma adopted a statement suggesting that the Russian President and government consider recognizing the independence of South Ossetia. Subsequently, then Russian President Vladimir Putin ordered relevant Russian parties to provide material assistance to residents of South Ossetia and Russian expatriates, and to establish a local mechanism to comprehensively protect the rights and freedoms of Russian expatriates.

　　In view of this situation, Georgia resolutely opposes it on the one hand, and actively seeks international support, especially the support of the United States on the other. The Georgian army has also strengthened construction, equipped with new weapons, received training from American instructors, and conducted joint military exercises with the United States and other countries.

　　Analysts believe that the independence of South Ossetia is a major obstacle for Georgia to join NATO, and Georgia launched such a large-scale military operation to eliminate this obstacle. Russia will never allow Georgia’s central government to fully control this region.

　　Analysts believe that the United States and Russia are two key supporters of Georgia and South Ossetia respectively. The policies of the United States and Russia will affect the trend of the situation in South Ossetia.

　　Special text According to Xinhua News Agency

　　■ background

　　South Ossetia has a long history.

　　South Ossetia, located in the Caucasus, is an autonomous prefecture of Georgia, bordering Russia’s North Ossetia, with an area of 3,900 square kilometers and 70,000 residents. South Ossetia demanded independence in the early 1990s, and there were many armed conflicts with the Georgian central government.

　　Since 1992, Russia, Georgia, South Ossetia and North Ossetia have formed the Quadripartite Mixed Supervisory Committee to resolve the conflict in South Ossetia, and the former three parties have formed a mixed peacekeeping force to station in the conflict area.

　　After taking office in early 2004, Georgian President Saakashvili promised to restore Georgia’s control over the entire South Ossetia region.

　　In November 2006, the second referendum in South Ossetia passed the demand for independence, but it was not recognized by the central government.

　　On August 7, 2008, Saakashvili announced a ceasefire and called on the South Ossetian authorities to cease fire immediately and respond to the proposal of direct negotiations. South Ossetia said it agreed to a temporary ceasefire.

Editor: Zhang Renhe

　　　　　　 CCTV News:These days, a storm surrounding Madagascar chameleon has been fermenting. The cause of the incident should also start with a post from a Weibo netizen named @ Daiwa Exploring the World. On February 18th, the day before the Lunar New Year Lantern Festival, this Weibo netizen @ Daiwa explored the world and published an article entitled "Help my mother quickly". This article said that two China men, Wu Mou and Ma Moumou, organized and led a group of 19 parents and children to Madagascar for the New Year in February this year, and participated in outdoor activities such as parent-child popular science tours.

　　　　　　 According to the article, the so-called China men Wu Mou and Ma Moumou claimed to be "entomologists of China Academy of Sciences", but they led their children and parents to "teach children to catch wild animals with their bare hands" and even violated local laws during their travels in Madagascar, regardless of their lives. According to the article, when the group returned to China, they put a live chameleon in the bag of a child’s parents and tried to smuggle it back to China. As a result, the so-called "organizer" Ma Moumou and the parents were arrested by the Madagascar police at the airport, with a maximum of 10 years’ imprisonment and a high fine of up to 200 million Malagasy dollars (about 400,000 yuan).

　　　　　　 There are many questions to be solved about the private chameleon.

　　　　　　 At present, there are still many doubts about this incident. Are the "Wu Mou and Ma Moumou" mentioned in this net really the so-called "insect experts of China Academy of Sciences"? During the Chinese New Year this year, the 19-member scientific delegation led by them, including parents and children, traveled to Madagascar. Is it really qualified? The most controversial point is whether a China parent who was detained by the Malagasy police involved brought the chameleon back to China privately, or "Wu Mou and Ma Moumou", as mentioned in the article, secretly put the live chameleon in her backpack in an attempt to bring it back to China without the parents’ knowledge. Although these questions haven’t been clearly answered, official website, the Embassy of China in Madagascar, has released the relevant notice of this incident. At present, this incident of "China tourists being detained by Madagascar police on suspicion of taking prohibited items such as chameleons out of the country" is in the judicial review stage, and there is no specific court date.

　　　　　　 There is no specific court date under judicial review.

　　　　　　 China’s Embassy in the Republic of Madagascar, official website, reported on February 18th that tourists from China were detained by Madagascar police on suspicion of bringing chameleons and other prohibited items out of the country. At present, the matter is in the stage of judicial review, and there is no specific court date.

　　　　　　 This outdoor activity was jointly initiated by Wu and Ma, and set off from China on February 6th at the tropical rain forest on the east and west coasts of Madagascar. Most of the members who participated in the outdoor activities were children and parents who liked insects, animals and plants. According to media reports, the wild animals seized this time, including a chameleon, a lizard and fifteen centipedes, were all placed in plastic boxes covered with cotton wool. Lawyers said that those involved may face a fine of 40,000 euros.

　　　　　　 Malaysia has strict regulations on the exit of "endangered animals and plants"

　　　　　　 Let’s also briefly understand Madagascar’s strict regulations on the entry and exit of endangered animals and plants. Just now, we saw a lawyer say that if you leave the country with endangered animals and plants according to previous local laws, you may face a fine of 40,000 euros, equivalent to about 300,000 yuan. However, we also checked the entry-exit customs office at the airport in Tanana Lifu, Madagascar’s capital, and clearly posted the management requirements for carrying jewelry, herbs, endangered animals and plants, frozen meat, alcohol and other items. The maximum penalty is far more than the 40,000 euros mentioned by lawyers.

　　　　　　 According to Malaysian customs regulations, if you carry "endangered animals and plants", you need to apply for the import and export license allowed by the Convention on International Trade in Endangered Species of Wild Fauna and Flora, and you need to apply for an epidemic prevention certificate if you carry "live animals"; Once violations are found, those who transport endangered animals and plants without permission will be punished with 2 to 10 years’ imprisonment and a fine of up to 200 million Arial (equivalent to about 400,000 yuan). Although not all kinds of chameleons, lizards and centipedes are endangered animals, the corresponding criminal punishment of "transporting endangered animals and plants" is the heaviest compared with illegal transportation of drugs, weapons and illegal food in Malaysian customs regulations.

　　　　　　 Not by chance? The organizers involved are frequently exposed.

　　　　　　 What is the truth of this case, we have to wait for the Malaysian judicial review and court session to come to the bottom. However, some background about this "China tourists are suspected of bringing chameleons back to China privately" has also attracted great media attention. After the incident, some media found that this did not seem to be an accident. Because the so-called "organizers" Ma Moumou and Wu Mou, who went to Madagascar for a popular science parent-child tour, were previously exposed to abetting and luring children and parents to hunt protected wild animals and bring them into the country, not only "teaching children to catch bats with their bare hands", but also "teaching children to catch wild animals". At the same time, another "organizer" Wu Mou also flowed out on the Internet, and in Weibo, he exposed various "intimate photos" of Malaysian animals and plants such as chameleons during his trip to Malaysia, but the legality could not be confirmed; However, after the incident, Wu Mou, the organizer of the group, deleted a large number of Weibo words and pictures. In addition, as far as Ma’s identity is concerned, some media have revealed that he is an "expert who impersonates a member of the Science Education Alliance of the Chinese Academy of Sciences", but in fact he is an insect dealer who sells wild animals and plants, but this statement has not been verified. In this regard, on February 19, the official micro "Voice of the Chinese Academy of Sciences" of the Chinese Academy of Sciences also forwarded "Ma Moumou pretends to be Weibo, a so-called expert of Chinese Academy of Sciences.

　　　　　　 Expert Interpretation: Wild animals and plants should be "viewed from a distance"

　　　　　　 In recent years, popular science parent-child travel is very popular, but what should we pay attention to when we are in close contact with wild animals? Come and listen to the expert’s analysis.

　　　　　　 Experts said that ecotourism, as a new way of tourism, is deeply loved by parents and friends because it is close to nature and entertaining. However, wild animals often carry viruses themselves and their temperament is elusive. It is very dangerous to reach out and touch without isolation measures, not to mention catching them by hand or even bringing exotic species back to China. Experts say that in addition to violating the Convention on International Trade in Endangered Species of Wild Fauna and Flora, bringing exotic species back to China will also lead to species invasion, which will damage biodiversity protection and ecological environment.

　　　　　　 So how should we treat wild animals? Experts suggest that tourists should respect all life in nature and get to know them without disturbing their normal life.

　　　　　　 Zhang Na, an expert in animal and plant protection, said, "I think we should follow the principle of three noes when dealing with wild animals, that is, no trapping, no touching and no disturbing. We should know from an early age that wild animals belong to nature and are our friends, so we should respect them. We will observe them and understand them without disturbing their normal life, and then we hope that everyone can respect all life in nature. "

Huawei Pura 70 seriesIt is on sale today, starting at 5499 yuan.

On April 22nd, Huawei officially launched Pura. 70Series two models, including Pura. 70And Pura 70 Pro. In terms of selling price, the starting price of Pura 70 is 5499 yuan, and the starting price of Pura 70 Pro is 7999 yuan.

Pura 70 Pro configuration upgrade

Compared with Pura 70, Pura 70 Pro is equipped with a more durable.Xuanwu toughened Kunlun glassScreen, storage capacity is also larger. The machine offers two configurations: the 16GB+512GB version costs 7999 yuan, and the 16GB+1TB version costs 8999 yuan.

Pura 70 has a straight screen design and does not support satellite communication.

Pura 70 adoptsStraight screen and straight edge designThe front is equipped with a 6.6-inch straight screen and second-generation Kunlun glass. The rear three-camera combination includes a 50-megapixel super spotlight camera, a 13-megapixel super wide-angle camera and a 12-megapixel periscope telephoto camera. In addition, the machine is equipped with a 4900mAh battery, which supports 66W wired fast charging, 50W wireless fast charging and 7.5W wireless reverse charging.

It is worth noting that Pura 70 Standard Edition does not support satellite communication and star flashing functions.

(reporting)

　　BEIJING, Beijing, July 27 (Wu Tao) Recently, the General Office of the State Council issued "Guiding Opinions on Establishing Modern Hospital Management System" (hereinafter referred to as "Guiding Opinions"), which made a series of arrangements for establishing modern hospitals. What will the modern hospital be built into? Is it more convenient for people to see a doctor? What changes have been made to the salary of medical staff? Zhongxin. com has combed and summarized this.

　　What will a modern hospital look like?

　　— — Adhere to public welfare and control the scale of special needs services in hospitals

　　The Guiding Opinions pointed out that modern hospitals first adhere to the public welfare of public hospitals, adhere to the people’s health as the center, and put people’s health in a strategic position of giving priority to development. Modern hospitals adhere to the separation of government affairs and management, reasonably define the government’s supervisory responsibilities, and give public hospitals the right to operate and manage independently.

　　The reporter observed that the Guiding Opinions put forward some particularly detailed requirements for modern hospitals. For example, it is necessary to strictly control the bed size, construction standards and large-scale medical equipment in public hospitals, prohibit debt construction and luxury decoration, and gradually compress beds that exceed the scale standards. Control the scale of special services in public hospitals, and the proportion of special services provided shall not exceed 10%.

　　The opinions in the Guidance also suggest that an accountability mechanism should be established for acts such as arbitrary charges and bad practices that have a major social impact, acts that have caused major medical accidents and major safety accidents, serious cases of violation of laws and discipline, and serious violations of the construction of professional ethics.

　　It is worth noting that modern hospitals put forward a series of requirements for the position of dean. The dean should be fully responsible for medical treatment, teaching, scientific research and administrative management. The president’s office meeting is the administrative and business decision-making body of public hospitals, which makes decisions on discussion and research matters. At the same time, the annual and term target responsibility of the president is assessed, which is linked to the president’s salary, appointment and dismissal, rewards and punishments.

　　Wu Ming, a professor at peking university health science center College of Public Health, believes that the Guiding Opinions not only gives public hospitals the right to operate and manage independently, but also promotes the reform of medical insurance payment method, cancels drug addition, adjusts the price of medical services, reduces the price of medical consumables, and the "two-vote system", and establishes an effective competition mechanism in the medical service market to form an effective constraint on public hospitals, so as to ensure that the dean has the right not to be willful.

　　It is more convenient for patients to see a doctor.

　　— — Strengthen the emergency power and smooth the green channel

　　What impact does the establishment of modern hospitals have on patients? First of all, the doctor-patient relationship that everyone is concerned about is mentioned in the Guiding Opinions, for example, promoting the construction of the "three mediations and one insurance" mechanism that organically combines hospital mediation, people’s mediation, judicial mediation and medical risk sharing mechanism, properly resolving medical disputes and building a harmonious doctor-patient relationship.

　　The Guiding Opinions also pointed out that patients’ satisfaction is an aspect of the assessment of medical staff, and the assessment of medical staff is directly related to their salary level and even job appointment and dismissal. City doctors have served at the grassroots or counterpart medical institutions for not less than 1 year before being promoted to the title of attending physician or deputy chief physician.

　　In addition, the "Guiding Opinions" proposes to carry out information-based convenience services such as medical guidance, settlement between clinics, push of inspection results, and settlement of medical treatment in different places. Develop high-quality nursing services and strengthen the services of social workers and volunteers. All these provide better services for people to see a doctor.

　　In addition, tertiary public hospitals should all participate in the construction of medical complexes and play a leading role. Further improve medical services, optimize medical procedures, rationally arrange facilities in consultation areas, scientifically implement appointment diagnosis and treatment, and implement day surgery, telemedicine and multidisciplinary joint diagnosis and treatment models. Strengthen the emergency rescue force and smooth the green passage in front of the hospital.

　　The hospital informatization construction proposed in the Guiding Opinions is also closely related to the convenience of people seeking medical treatment. Zhang Wei, secretary of the Party Committee of west china hospital, analyzed that the Guiding Opinions put forward the effective docking of medical insurance, budget management, drug electronic supervision and other systems, and well designed and implemented medical services, medical quality and safety, internal audit and other systems, so as to minimize the burden of patients seeking medical treatment and the repeated work of medical staff caused by information and communication barriers and cumbersome workflow.

　　How to change the salary of medical staff?

　　— — Do not set revenue targets, and shall not be linked to the business income of the department.

　　Will the salary of medical staff change in the process of establishing modern hospitals? How to change? Presumably this is a problem that many people care about. According to the Guiding Opinions, public hospitals should make independent distribution within the approved total salary, reflecting post differences, taking into account the balance of disciplines, and achieving more work and more rewards.

　　According to the relevant regulations, hospitals can explore the implementation of target annual salary system and agreed salary. The salary of medical personnel shall not be linked to the business income of drugs, sanitary materials, inspection and testing. It is strictly forbidden to set income-generating targets for medical staff.

　　The Guiding Opinions also show that public hospitals should establish a public welfare-oriented assessment and evaluation mechanism, regularly organize public hospital performance assessment and dean’s annual and term target responsibility assessment, and the assessment results are linked to financial subsidies, medical insurance payment, total performance salary and dean’s salary, appointment and dismissal, rewards and punishments, etc. The assessment results will also be linked to the employment of medical staff, promotion of professional titles and personal salary.

　　Wang Hufeng, director of the Medical Reform Research Center of Renmin University of China, analyzed that it is an important aspect to establish a modern hospital management system to grant public hospitals autonomy in salary distribution and management under the framework of laws and regulations. "Only in this way can the enthusiasm of managers and medical staff be fully mobilized, so that medical institutions can provide quality services and efficient services." Wang Hufeng said. (End)

　　Guangming Daily, Beijing, September 17th (Reporter Li Yun and Wang Xiaofei)Recently, National Cultural Heritage Administration held a working meeting on the important progress of the major project "Archaeological China" in Beijing. The four archaeological projects of this workshop are the latest achievements in the excavation and research of early city sites in the middle reaches of the Yellow River, which are all in the early development stage after the formation of Chinese civilization. These latest achievements show the historical process of China’s prehistoric civilization and the formation and development of early countries.

　　Excavation site of Xiaoyuliang stone building in Bicun site, Xing County, Shanxi Province Xinhua News Agency issued

　　　Shicheng Site in Houchengzui, Hohhot, Inner Mongolia: Prehistoric Prototype of "Tunnel War"

　　■ Project introduction:The Shicheng site of Houchengzui is located in Qingshuihe County, Hohhot City, Inner Mongolia Autonomous Region, with an area of about 1.38 million square meters. Archaeological findings show that this site of Longshan period, which is more than 4,000 years ago, has a triple defense system: the first defense system consists of the outer urn city wall, horse face, abutment and outer ring trench; The second defense system consists of the urn city wall, the abutment and pier arranged on the urn city wall, and the inner ring trench; The third defense system consists of the main city wall, the main city gate and two horse faces arranged on both sides of the main city gate.

　　The most amazing thing is that two underground passages were found under the outer urn. Sun Jinsong, dean of the Institute of Cultural Relics and Archaeology of Inner Mongolia Autonomous Region, said that the two tunnels have both offensive and defensive functions. The widest part of the passage is 3.4 meters, the deepest part is 6.3 meters, and the top of the passage is 2.4 meters, so that people can travel without hindrance. After deduction, it can be seen that people outside the city can enter the urn through the tunnel at that time, and then shunt into the city wall to reach the interior of the main city. Of course, the reverse is also possible. Are these two tunnels the remains of "tunnel warfare" more than 4,000 years ago?

　　■ Expert comment: Song Jianzhong (researcher of National Cultural Heritage Administration Archaeological Research Center)

　　In recent ten years, archaeology has continuously promoted fine excavation and multidisciplinary cooperation. There are three levels in the area of Shenmu Shigao site in Shaanxi, Shicheng site in Houchengzui, Inner Mongolia and Bicun site in Xingxian, Shanxi. Shigao site has the largest area and the highest level, while Bicun site has the smallest area. Moreover, the three sites are all buildings made of stone and wood, and they are similar in cultural appearance. Therefore, I think Shanxi, Shaanxi and Inner Mongolia should work together, adhere to the problem orientation, study the context of the three sites, and make clear whether there is synchronicity among them. These will certainly promote the study of the large regional form in the north.

　　Pottery unearthed from Bicun site in Xing County, Shanxi Province, Xinhua News Agency issued

　　　Bicun Site in Xing County, Shanxi Province: An Important Guancheng along the Yellow River around 4000 years ago.

　　■ Project introduction:Bicun Site is located in Xingxian County, Luliang City, Shanxi Province, dating from 4000 to 3700 years ago. It is the first confirmed large-scale Shicheng settlement in Longshan period along the Yellow River in Shanxi Province, and it was also an important Guancheng at that time.

　　Xiaoyuliang site is the core area of Bicun site. Archaeologists have discovered a group of stone buildings, the second house in the middle is the central house, and the houses on the other two sides are arranged progressively to the west on this axis. The walls and floors of these houses have been carefully treated, and the walls are smeared with grass and mud. There is a ground stove in the house, and the maximum diameter of the stove reaches 2.6 meters. In addition to the house in the central building, there is a house in the northwest corner, which was a large studio in the early stage and divided into small compartments in the later stage. "It is particularly noteworthy that there are steps in the northwest corner of the room near the north wall. We speculate that this may be a post." Zhang Guanghui, a researcher at Shanxi Institute of Archaeology, introduced. Bicun site is located at the key road between the west and the Central Plains, and the inner and outer city walls have a relatively strict defensive layout. The city gate is backed by the Yellow River and faces the east, and checkpoints are set up everywhere. Therefore, "we speculate that this is an important checkpoint". In addition, the gate of the site is composed of three large piers in the shape of "pin" in the east, south and north, which shows a unique gate shape of Shicheng site in Hetao area.

　　■ Expert comment: Han Jianye (Professor, School of History, Renmin University of China)

　　The gate structure of Bicun Ruins is not only practical in layout, but also very neat in symmetrical structure, with a ceremonial nature. Houchengzui site and Bicun site are similar in age, and both are in the early development stage of Chinese civilization, which may be closely related. The next step should be to explore the relationship between sites in a wider scope in the north, such as what is the relationship between Bicun site and Shimao site? What is the relationship between Bicun Site and Shimao Site and Xia Dynasty? What is the relationship between cattle and sheep unearthed from Bicun site and Eurasian grassland? These relationships still need to be sorted out.

　　Gold Covered Surface Unearthed from M2 of High-grade Noble Tomb in Zhengzhou Shangcheng Site Xinhua News Agency

　　　Erlitou Site in Yanshi, Henan Province: How many more pieces are added to the Wangdu puzzle?

　　■ Project introduction:Erlitou site is located in Yanshi District, Luoyang City, Henan Province, with an existing area of 3 million square meters, which is generally considered as the capital site in the late Xia Dynasty by academic circles.

　　Before, I only knew the "Jiugongge" layout of Erlitou site, but the details were not clear. The latest archaeological excavations show that there are rammed earth walls on both sides of roads in many cities, and the outer sides of many areas outside the palace area and workshop area are also separated and protected by fences. There are different levels of buildings and tombs in different grids, and each grid may be inhabited by different people. Zhao Haitao, an associate researcher at the Institute of Archaeology, Chinese Academy of Social Sciences, said that all these indicate that Erlitou Capital probably has a layout of "living in different areas, living outside the area, and integrating residence and burial".

　　The latest excavation also found the remains of pottery making for the first time in the site, and unearthed more than 800 pieces of pottery with red paint on the surface, suggesting that there may be lacquer making workshops around; Nearly 100 square meters of bone and horn processing workshops were found in the southwest corner of Miyagi. The discovery of these new workshops is helpful to study the manufacturing process and technology of handicraft industry.

　　■ Expert comment: Lei Xingshan (Professor, School of History, Capital Normal University)

　　The discovery of Erlitou site "Jiugongge" is a major breakthrough in Xia cultural archaeology. Lifang system was once an important system in the city, but it appeared relatively late. The "Jiugongge" in Erlitou is the "Li" that can be confirmed.

　　In the past archaeological work, turquoise workshops were found. Now, workshops for making bone horns and lacquerware have been found, which has strengthened some characteristics of Erlitou as the capital. It can also be seen from archaeological discoveries that although the ages and crowds are not the same, there are similar cultural features in the ruins far and wide. The similarity and continuity of cultural characteristics and the identity and inheritance of cultural genes are vivid examples of the pluralism and continuity of Chinese civilization.

　　The remains of the bone-making workshop, which was carefully excavated for the first time at Erlitou site in Yanshi, Henan Province, were issued by Xinhua News Agency.

　　　Shang Dynasty Cemetery in Shuyuan Street, Shangdu, Zhengzhou: First Discovery of Gold Covering in the Early Shang Dynasty in Central China

　　■ Project introduction:The Shang Dynasty cemetery in Shuyuan Street, Shangdu, Zhengzhou is located in the southeast of the inner city of Zhengzhou Shopping Mall site. It is a high-grade aristocratic cemetery in the early and middle period of Shang Dynasty, where a rare gold overlay was unearthed.

　　Two east-west trenches were found on the north and south sides of the cemetery, and the tombs were mainly distributed between the two trenches. Tomb No.2 is the tomb with the largest number, the richest variety and the highest level of funerary objects found at present. Besides a large number of bronzes, there are also gold coverings with a gold content of 88% and a weight of 40 grams, as well as gold ornaments such as gold bubbles and gold foils, which provide new reference materials for discussing the gold masks appearing in Sanxingdui and the cultural style of gold decorations in southwest China. Huang Fucheng, a researcher at Zhengzhou Institute of Cultural Relics and Archaeology, said that the phenomenon of dog martyrdom at the bottom of Tomb No.2 was very rare in the early and middle Shang cultures, which provided a new understanding of the source of dog martyrdom culture in later high-level tombs such as Yin Ruins in Anyang.

　　■ Expert comment: Chen Xingcan (researcher, Institute of Archaeology, Chinese Academy of Social Sciences)

　　The age of Shang Dynasty cemetery in Shuyuan Street, Shangdu, Zhengzhou is in a critical period between the early Shang Dynasty and the middle Shang Dynasty, one period earlier than the Yin Ruins and one period later than the lower culture in Erligang, Zhengzhou. In the past, tombs were rarely found in the early and early stages of the Shang culture in Zhengzhou, especially high-grade large tombs, so the discovery of this large tomb is of great significance. Gold wares began to appear in Shang Dynasty, but they were very few. Such a large number of gold ornaments, such as the gold overlay unearthed in M2 tomb, provided us with new research materials to study the relationship between the appearance of gold wares and Eurasia grassland and the West.

　　Schematic diagram of the Shicheng site in Houchengzui entering the city through the tunnel Photo courtesy of National Cultural Heritage Administration

　 　 　 　Recently, AHA has just released the 2020 Cardiopulmonary Resuscitation (CPR)-Cardiovascular First Aid (ECC) Guide. The guide is divided into five parts, namely, basic and advanced life support for adults, basic and advanced life support for children, life support for newborns, resuscitation education science and rescue system.

Adult basic and advanced life support　

　 　 　 　Despite the progress in recent years, less than 40% of adults received CPR initiated by non-professionals, while less than 12% received AED first aid before EMS arrived. AHA adult IHCA and OHCA survival chain

(Click to enlarge, the same below)

Emergency procedures for adult cardiac arrest

Opioid-related emergency procedures for non-professional emergency personnel

Opioid-related emergency procedures for medical staff

Flow chart of treatment after recovery of spontaneous circulation in adult cardiac arrest

Suggested methods for multimodal neural prediction of adult patients after cardiac arrest and recovery of autonomic circulation

ACLS flow chart of pregnant women with cardiac arrest in hospital

Main new and updated suggestions in 2020 　　　

Non-professional rescuers should start as soon as possible.

CPR2020 (updated)：We recommend that non-professionals perform CPR on patients with possible cardiac arrest, because if the patient is not in a state of cardiac arrest, the risk of injury to the patient is low.

2010 (old):　If the adult suddenly falls down or the unresponsive patient’s breathing is abnormal, the non-professional rescuer should not check the pulse, but assume that there is cardiac arrest. The medical staff should check the pulse within no more than 10 seconds. If the pulse is not clearly touched within this time, the rescuer should start chest compressions.

Reason: New evidence shows that patients who receive chest compressions when they are not in cardiac arrest have a lower risk of injury. Non-professional rescuers cannot accurately determine whether the patient has a pulse, and the risk of not performing CPR on patients without a pulse exceeds the harm caused by unnecessary chest compressions.

Physiological monitoring of CPR quality

2020 (updated):　It may be reasonable to use physiological parameters such as arterial blood pressure or ETCO2 to monitor and optimize CPR quality when feasible.

2015 (old):　Although there is no clinical study to investigate whether adjusting resuscitation operation according to physiological parameters during CPR can improve the prognosis, it may be reasonable to use physiological parameters (quantitative carbon dioxide waveform, arterial diastolic pressure, arterial pressure monitoring and central venous blood oxygen saturation) to monitor and optimize CPR quality, guide vasopressor drug treatment and detect ROSC when feasible.

Reason: Although it is an established concept to monitor the quality of CPR by physiological monitoring methods such as arterial blood pressure and ETCO2, new data support its inclusion in the guidelines. According to the data of AHA’s "Follow the Guide-Resuscitation" registration study, the possibility of ROSC is increased when using ETCO2 or diastolic blood pressure to monitor CPR quality.

The monitoring depends on the existence of endotracheal intubation (ETT) or arterial catheterization. Adjusting the compression target so that the ETCO2 value is at least 10 mm Hg, ideally 20 mm Hg or higher, may be useful as a CPR quality marker. The ideal goal has not yet been determined.

Dual continuous defibrillation is not supported.

2020 (new):The usefulness of dual continuous defibrillation for refractory shockable rhythm has not been determined.

Reason: Double continuous defibrillation refers to the practice of using two defibrillators to perform electric shock almost simultaneously. Although some case reports show a good prognosis, the ILCOR system review in 2020 found no evidence to support dual continuous defibrillation, so routine use is not recommended. There are many forms of bias in existing studies, and observational studies have not shown improvement in prognosis. A recent experimental RCT shows that changing the direction of defibrillation current by repositioning electrode pads may be equivalent to the effect of dual continuous defibrillation, while avoiding the risk of injury caused by energy increase and defibrillator damage. According to the current evidence, it is not clear whether dual continuous defibrillation is beneficial.　　

Venous access takes precedence over intraosseous access.

2020 (new):It is reasonable for practitioners to try to establish venous access for drug administration in patients with cardiac arrest first.

2020 (updated):If venous access is not successful or feasible, we can consider using intraosseous access instead.

2010 (old):If there is no ready-made venous (IV) access, it is reasonable for practitioners to establish intraosseous (IO) access.

Reason: In 2020, ILCOR systematically reviewed and compared intravenous and intraosseous administration during cardiac arrest, and found that venous pathway was related to better clinical prognosis in five retrospective studies. RCT subgroup analysis focusing on other clinical problems also found similar results when intravenous or intraosseous routes were used for drug delivery. Although venous access is the first choice, intraosseous access is also a reasonable choice for the situation that it is difficult to establish venous access.　　

Treatment and support during rehabilitation

2020 (new):　We suggest that survivors of cardiac arrest undergo multimodal rehabilitation evaluation and treatment in terms of physical, neurological, cardiopulmonary and cognitive impairment before discharge.

2020 (new):　We suggest that cardiac arrest survivors and their caregivers receive a comprehensive multidisciplinary discharge plan to incorporate medical and rehabilitation treatment suggestions and expected goals of activity/work recovery.

2020 (new):　We suggest a structured assessment of anxiety, depression, post-traumatic stress response and fatigue for survivors of cardiac arrest and their caregivers.

Reason: Patients with cardiac arrest need to go through a long rehabilitation period after initial hospitalization. Support is needed during rehabilitation to ensure the best physical, cognitive and emotional health and restore social/role functions. This process should start from the initial hospitalization period and continue as needed. These topics are discussed in more detail in the 2020 AHA scientific statement.

Analysis and summary of rescuers

2020 (new):　After cardiac arrest, it may be beneficial to organize non-professional rescuers, EMS implementers and hospital medical staff to analyze and summarize and provide follow-up for them in the follow-up for emotional support.

Reason: The rescuer may feel anxious or have post-traumatic stress reaction because of providing or not providing BLS. Hospital medical staff may also encounter emotional or psychological influence when treating patients with cardiac arrest. Team analysis and summary can review team performance (education and quality improvement) and identify natural stress factors related to the treatment of dying patients. It is expected that an AHA scientific statement dedicated to this topic will be released in early 2021.　　

Cardiac arrest in pregnant women

2020 (new):　Because pregnant women are more prone to hypoxia, oxygenation and airway management should be given priority during the resuscitation of pregnant women’s cardiac arrest.

2020 (new):　Because it may interfere with the recovery of pregnant women, fetal monitoring should not be carried out during the cardiac arrest of pregnant women.

2020 (new):　We suggest that pregnant women who are still unconscious after cardiac arrest and resuscitation should be managed by target temperature.

2020 (new):　During the management of target body temperature for pregnant patients, it is suggested to continuously monitor the fetus for the possibility of bradycardia, and consult obstetrics and neonatology.

Reason: Reviewed the recommendations on the management of cardiac arrest in pregnant women in the guideline update in 2015 and AHA scientific statement in 2015. Due to the increase of maternal metabolism, the decrease of functional residual capacity caused by pregnant uterus and the risk of fetal brain damage caused by hypoxemia, airway, ventilation and oxygenation are particularly important in the context of pregnancy.

　 　 　 　It is not helpful to evaluate the fetal heart during the period of maternal cardiac arrest, and it may also distract attention from the necessary resuscitation operation. In the absence of contrary data, pregnant women who survive after cardiac arrest should be managed by the target temperature like other survivors, and the condition of the fetus who may stay in the uterus should be considered.

Basic and advanced life support for children　

The causes of cardiac arrest in infants and children are different from those in adults, and more and more pediatric specific evidence supports these suggestions.

AHA children’s IHCA and OHCA survival chain

Flow chart of cardiac arrest in children

Flow chart of bradycardia in children with pulse

Flow chart of pulse tachycardia in children

Checklist of treatment after spontaneous circulation recovery in children with cardiac arrest

Important Issues, Major Changes and Enhancements in the 2020 Guide 　

The flow chart and visual AIDS were modified to incorporate the best scientific knowledge and provide clearer information for PBLS and PALS resuscitation implementers.

According to the latest data of children’s resuscitation, it is suggested that the frequency of auxiliary ventilation should be increased to once every 2-3 seconds (20-30 times per minute) for all children’s resuscitation scenarios.

For patients of any age who need to be intubated, it is recommended to use a cuff ETT to reduce air leakage and the need to change tubes.

The routine use of cricoid cartilage compression during intubation is no longer recommended.

In order to maximize the chances of obtaining a good resuscitation prognosis, epinephrine should be given as soon as possible, and ideally it should be given within 5 minutes after cardiac arrest with non-shockable rhythm (cardiac arrest and pulseless electrical activity).

For patients with arterial catheterization, the feedback from continuous measurement of arterial blood pressure can improve the quality of CPR.

After Rosc, the patient’s seizure should be evaluated; Status epilepticus and any convulsive seizures should be treated.

Patients with cardiac arrest need to go through a long rehabilitation period after their initial hospitalization, so their physiological, cognitive and psychosocial needs should be formally evaluated and given corresponding support.

When epinephrine or norepinephrine is infused when vasopressor drugs are needed, it is appropriate to adopt titration liquid management method for resuscitation of septic shock.

According to adult data, it is generally inferred that the balanced blood component resuscitation scheme is reasonable for infants and children with hemorrhagic shock.

Opioid overdose management, including seizures by non-professional rescuers or trained rescuers, should be treated.

Patients with cardiac arrest need to go through a long rehabilitation period after their initial hospitalization, so their physiological, cognitive and psychosocial needs should be formally evaluated and given corresponding support.

When epinephrine or norepinephrine is infused when vasopressor drugs are needed, it is appropriate to adopt titration liquid management method for resuscitation of septic shock.

According to adult data, it is generally inferred that the balanced blood component resuscitation scheme is reasonable for infants and children with hemorrhagic shock.

Opioid overdose management includes CPR by non-professional rescuers or trained rescuers and timely administration of naloxone.

Children with acute myocarditis with arrhythmia, cardiac block, ST segment changes or low cardiac output are at higher risk of cardiac arrest. It is important to be transferred to the intensive care unit as soon as possible. Some patients may need mechanical circulatory support or extracorporeal life support (ECLS).

Babies and children with congenital heart disease and single ventricular physiological function need special consideration in the management of PALS if they are in the process of staged reconstruction.

The management of pulmonary hypertension may include the use of inhaled nitric oxide, prostacyclin, analgesic drugs, sedative drugs, neuromuscular blocking drugs, induced alkalosis or ECLS rescue treatment.

Neonatal life support

Newborn resuscitation needs to be predicted and prepared by the implementers who have received individual and team training.

Most newborns do not need umbilical cord ligation or resuscitation immediately, but can be evaluated and monitored during the skin contact between mother and baby after birth.

Preventing hypothermia is an important concern of neonatal resuscitation. As a way to close the parent-child relationship, promote breastfeeding and maintain normal body temperature, the importance of skin contact nursing for healthy infants is strengthened.

For newborns who need support after birth, lung dilatation and ventilation are the primary tasks.

The increase of heart rate is the most important index of effective ventilation and response to resuscitation intervention.

Pulse oxygen saturation is used to guide oxygen supply and achieve oxygen saturation target.

Routine endotracheal suction is not recommended for active or inactive infants born in meconium-contaminated amniotic fluid (MSAF). Endotracheal aspiration is only applicable when airway obstruction is suspected after providing positive pressure ventilation (PPV).

If proper ventilation correction steps are taken (preferably including tracheal intubation), but the heart rate does not respond well to ventilation, chest compressions can be performed.

Electrocardiogram should be used to monitor the response of heart rate to chest compressions and drugs.

When newborns need vascular access, umbilical vein pathway should be the first choice. When venous access is not feasible, the intraosseous approach can be considered.

If the response to chest compressions is not good, it may be reasonable to provide epinephrine, preferably through the intravascular route.

If there is no response to adrenaline and there is a history or examination consistent with blood loss, the newborn may need to expand.

If all these resuscitation steps have been effectively completed, but there is still no heart rate reaction after 20 minutes, we should discuss with the team and the family members of the child to adjust the treatment direction.

　 　 　 　 Survival after cardiac arrest depends on the establishment of an organic system covering personnel, training, equipment and organization. Willing bystanders, owners equipped with AED, emergency service telecommunication personnel and BLS and ALS implementers working in EMS system can all contribute to the successful recovery of OHCA.

　 　 　 　Within the hospital, the work of doctors, nurses, respiratory therapists, pharmacists and other professionals also provides support for the prognosis of resuscitation. Successful recovery also depends on the efforts of equipment manufacturers, pharmaceutical companies, recovery teachers, guide compilers and many others. Long-term survival depends on the support of family members and professional nurses, including experts in cognitive, physical and psychological rehabilitation and recovery. All links in the whole system are striving to improve the quality of treatment in an all-round way, which is very important for achieving a successful prognosis.

　　The artificial meat company has just listed in the United States, and the artificial milk has come. Recently, Mike Shedlock, a columnist of MishTalk, a global economic research website, introduced artificial milk that is more environmentally friendly, healthier and more expensive. This makes many people lament that with artificial milk, the problems existing in milk can finally be solved.

　　Rumors about milk have never been broken. "Milk causes cancer", "Milk is not suitable for Chinese’s physique" and "Milk will send mankind to the grave" … … Are these terrible stories about milk circulating on the Internet true?

　　Rumor 1: Hormones in milk can cause cancer.

　　An article entitled "Milk sends human beings to the grave" was once heated up, causing widespread panic among the masses. According to the article, milk contains the hormone IGF-1. Women who drink too much will suffer from breast cancer and ovarian cancer, while men are prone to prostate cancer.

　　"The full name of IGF-1 is called insulin-like growth factor No.1, which has a similar effect to insulin, mainly regulating people’s blood sugar and promoting people’s growth and development. Judging from the current experimental or scientific evidence, it does not indicate that it has a carcinogenic effect. " Li Yajun, a professor at the School of Life Sciences of Guizhou Normal University, said in an interview with the Science and Technology Daily reporter.

　　In this regard, some experts have explained that IGF-1 is a protein with important physiological functions, which exists widely in human body. Milk does contain this hormone substance, but the content is very small. Previously, an epidemiological survey showed that IGF-1 seems to have a certain relationship with prostate cancer and other cancers, but so far there is no evidence that IGF-1 is the direct cause of cancer. "Having a certain relationship" does not mean that it will directly induce cancer. In addition, the amount of IGF-1 obtained by drinking milk is insignificant compared with the amount of IGF-1 contained in the human body itself. Moreover, IGF-1 in milk has no biological activity in human body after heating, digestion and absorption, let alone causing cancer.

　　In 2017, Song Xiaomei and other scholars from the School of Chemistry and Environmental Sciences of Hebei University published a paper pointing out that the main argument of "milk carcinogenesis" comes from some epidemiological research results (especially for prostate cancer), but it often avoids intake, which is misleading to people who generally lack systematic health knowledge. Its argument is mainly the view of the China Health Survey Report compiled by Cornell University, the main purpose of which is to advocate people in Europe and America to change their bad eating habits mainly based on animal foods. However, the intake of dairy products by Chinese residents is far from the highest intake in European and American epidemiological studies (more than 600 grams per day), even lower than the recommended daily intake of 300 grams in the Dietary Guidelines for China Residents (2016).

　　Proverbs 2: Chinese was born unfit to drink milk.

　　In life, we often hear the saying that Chinese is mainly vegetarian, and its constitution is peaceful and cool, so it is useless to digest the cold and wet food such as milk. Therefore, more than 60% of Chinese people have diarrhea when drinking milk, which is because milk hurts spleen yang.

　　In this regard, Li Yajun said that for a long time, the academic community thought that milk was flat and sweet and did not belong to cold food. Many people in Chinese will have diarrhea when drinking milk, not because the milk is cold or the milk hurts spleen yang, but because the milk contains lactose, and these people lack enzymes to decompose lactose, which is reflected in the fact that they will not have diarrhea when drinking yogurt or soothing milk with lactose decomposed.

　　Adults in China drink less milk, and the body’s ability to decompose lactose will decrease — — Lactases that decompose lactose in the intestine are "unemployed" one after another, which leads to the basic shutdown of the "factory" that produces lactase. The lack of lactase in most people is caused by "using it and discarding it", rather than congenital lack of this gene. The vast majority of Chinese do not have congenital lactase deficiency, that is to say, Chinese is not born unfit to drink milk, just because he usually drinks too little. For non-congenital lactose deficiency, the ability to digest lactose can be restored through gradual adaptation.

　　Rumor 3: Drinking milk leads to various skin diseases.

　　Some people, especially infants, are prone to eczema after drinking milk, so there is a saying on the Internet: Never drink milk, which will lead to skin diseases such as eczema.

　　"This is a chronic allergic problem of food. Some people will be allergic and acne when drinking milk, but it cannot be proved that this food is inedible, because there are always a few allergic people. In fact, many people in life have different allergens, such as eggs, beef, seafood and even all kinds of fruits. We can’t say that everyone should not eat these things just because a few people are allergic. This is typical and a bit ridiculous. " Fan Zhihong, an associate professor in the Department of Nutrition and Food Safety, College of Food Science, China Agricultural University, said.

　　Li Yajun also said that this statement is not accurate. It is not milk itself that causes allergies, but some people may be allergic to protein contained in milk, so drinking milk will cause skin diseases, but this does not mean that there is something wrong with milk. Just like many people are allergic to pollen and seafood, there are various allergens. As individuals, it is good to avoid contact as much as possible in life. But it doesn’t mean that what is bad for this person is not good for others to eat.

　　Proverbs 4 Casein can increase the prevalence of many diseases.

　　An article entitled "The Great Harm of Milk! The online article "Milk, Meat, Fish and Eggs", which is suggested to be completely fasted, has far-reaching influence and makes many people have doubts about eating milk. The article points out that the research by Professor Campbell of Cornell University in the United States shows that protein in milk, especially casein, is a very strong cancer promoter, and it can increase the incidence of heart disease, diabetes, kidney calculi and hypertension. Li Piao, editor of the rumor mill of the shell network and an agronomy major, once said that Professor Campbell’s research on the carcinogenesis of casein in milk "is not the mainstream view in academic circles, and there is no stronger evidence to prove that milk can increase the risk of cancer". According to reports, Campbell’s experiment was to induce cancerous cells in rats by high dose of aflatoxin (a strong carcinogen), but it could not be directly concluded that casein had the same effect on healthy people. Moreover, Campbell also made it clear in an interview with the media that his research does not mean that dairy products can cause cancer.

　　Fan Zhihong said that this statement is purely a rumor, because existing studies have proved that casein in milk not only does not increase the risk of the above diseases, but is beneficial to the prevention of hypertension and stroke. A study of 64,191 women in China found that the intake of calcium, magnesium and dairy products was negatively correlated with the risk of diabetes. The nutritional epidemiological study of Institute of Nutrition of Chinese Academy of Sciences also found that the intake of dairy products was negatively correlated with waist circumference, systolic blood pressure and diastolic blood pressure, glycosylated hemoglobin content, high-density lipoprotein cholesterol, body mass index (BMI) and blood sugar.

　　In Li Yajun’s view, not only milk, but also human milk contains casein. Casein in dairy products is a kind of high-quality protein, which contains eight kinds of amino acids needed by human body, especially the combination of casein and calcium, which is beneficial to promote the absorption of calcium by human body. Reporter Fu Lili

Original title:South Korea’s 7,000 ex-doctors will lose their licenses.

The reporter learned from the Korean government that 7,000 interns and residents who have left their posts will enter the procedure of revoking their doctor’s licenses, and the relevant treatment is irreversible. (General Desk reporter Zhang Yun)

Previously reported

According to CCTV news, February 29th is the deadline set by the South Korean government for the returnees in the "resignation tide".

On the one hand, Korean junior doctors keep protesting and making their own demands; On the other hand, most people in South Korea support the tough attitude of the government.

How this medical crisis, which has lasted for nearly two weeks, will end has aroused widespread concern in Korean society.

On March 1, the South Korean police conducted a compulsory investigation on the relevant persons of the Korean Medical Association who were reported for allegedly violating the Medical Law.

Jeong-hwan Kim, a senior official of the South Korean Ministry of Health, revealed that from March 4th, the government will warn doctors who continue to violate the "Return to Work Order".

According to Korean law, the government can revoke the doctor’s license for up to one year for doctors who seriously endanger public health, and doctors may face three years’ imprisonment or a fine of 30 million won, which is about 160,000 yuan.

South Korea’s Minister of Interior and Security Lee Sang-min:

In principle, we will investigate and deal with the refusal of the leaders and forces behind illegal collective actions to comply with the government’s order to resume work.

Individual interns who refuse to return to work will be tried through formal prosecution. The tough stance of the Korean government was opposed by the Korean Medical Association.

On February 29th, an inspection of 100 large-scale internship hospitals in China showed that as of 7: 00 pm the previous day, 9997 interns affiliated to these hospitals had submitted resignation reports, accounting for 80.2% of the total.

The actual number of doctors absent from work was 9076, accounting for 72.8%.

According to the statistics of the Korean Ministry of Health and Welfare, as of 5: 00 pm on February 29th, the number of residents returning to the medical field after the strike increased by 271 compared with the previous day, totaling 565.

Patient:

I was diagnosed with stage III pancreatic cancer. The situation in the hospital is very complicated. There are no empty seats in the waiting room, and many patients who can’t receive treatment in other hospitals also come here. The shortage of medical resources has caused dissatisfaction among the Korean people.

　　In 2022, the movie market of Spring Festival ended with a box office score of 6.6 billion, and won the second place in the box office history of China Spring Festival. Although it did not exceed last year’s 7.8 billion, it has been considered by the industry as a positive signal in the "post-epidemic era". Next year, what other movies are expected to hit the big screen and surprise the audience?

　　The main melody blockbuster is still wonderful.

　　Tony Leung Chiu Wai, YiBo and Zhou Xun lead The Unknown.

　　The high box office and high reputation of The Battle at Lake Changjin and Watergate Bridge of Changjin Lake once again prove that China’s new mainstream blockbusters have become the audience’s first choice. And this year’s next new mainstream blockbuster will have a good performance, and the most worthy of the audience’s expectation should be "Nobody".

　　The film "Nobody" focuses on the mysterious hidden front and tells the story of underground workers risking their lives to send information and defend the motherland with their lives and blood. The film’s lineup is quite strong, directed by director Cheng Er, starring Tony Leung Chiu Wai, YiBo, Zhou Xun and Eric Wang. Just looking at the list of participants, the audience has begun to look forward to the performance of the acting school.

　　This time, The Unknown focuses on the revolutionary period from 1937 to 1945. Cheng Er revealed that Shanghai was in a "difficult moment" at that time, and countless underground workers courageously fought for the victory of the China Revolution with their obscure dedication. This film hopes to show the struggle of the "unknown" in detail and take the audience to see a world that they have never seen before. As the third part of Bona’s Trilogy of Victory in China, it remains to be seen whether Unknown can open up a new realm for Chinese spy films.

　　Xin Yukun’s third feature film, Interpol in China, has attracted much attention this year. The film is based on the story prototype of the "Su Xiangyu series of gun robbery and murder cases" that the police cracked for eight years in 2012.

　　In addition, Siu Fai Mak directed, Zhao Peng scripted, starring Johnny, Bai Baihe and Claudia, and "The Prosecutorial Storm" featuring Wang Qianyuan and Bao Beier will also be released this year. This is the first commercial crime film focusing on prosecutors in China. Based on a real case, it tells the story of how prosecutors take responsibility and act in the fight against evil.

　　The sixth generation directors frequently have surprises.

　　New works by Wang Xiaoshuai, Guan Hu and Lou Ye.

　　Fertile Soil is a film directed by Wang Xiaoshuai, with Ouyang Wenxin, Yongmei, Zu Feng, Molly, Li Jun, Wang Jingchun, Ligeng Si, etc. It is the second part of Wang Xiaoshuai’s trilogy of homeland after Forever, based on Li Shijiang’s short story Grandpa’s Trick, and tells a story about rural family life.

　　Yongmei cooperated with Wang Xiaoshuai again after Forever, and played Muyue, the mother of a small fertile soil, in Fertile Soil. Zu Feng, an actor who has just cooperated with Wang Xiaoshuai in the online drama "The Mystery Fog in the Eight Corners Pavilion", plays the father Laochuan in the film. In addition, the actor Molly plays the old wine in the film, and the actor Li Jun plays the grandfather of fertile soil. The film was launched in Jingyuan County, Baiyin City last September, and it is expected to meet the audience this year.

　　Guan Hu, who is the same as Wang Xiaoshuai as the sixth generation director, introduced a new work, Dogville, which was written and directed by himself. The film tells the story of a small town in northwest China more than ten years ago. In order to make a living, Jiro joined the folk dog catcher, where he hauled stray dogs all day long. A stray dog came into his life and gradually developed feelings with him. Jiro’s compassion for life is slowly awakened, and in order to save more stray dogs, he takes active action. "Dogville" started filming in a low-key way as early as September 2021, and it is reported that the film will be released this year.

　　The film "Three Words" by Lou Ye, the sixth generation director, has attracted people’s attention since the cast was exposed, starring Jackson Yee, Chun Xia, Li Xian, Zhang Yu and others. The film takes a character’s memory as a clue to the development of the story, telling the story that he once lost his love for the person he likes because of lack of courage, and once struggled with his friends with fate.

　　The film directed by Lou Ye has a distinct personality and is good at portraying characters, while Jackson Yee has become more and more colorful in performance because of Xiaobei in Better Days, Wei Yihang in A Little Red Flower and Wu Wan Li in The Battle at Lake Changjin. I wonder what surprises will be brought to everyone in this film.

　　The famous director made a breakthrough in his new film.

　　Look at Zhang Yimou, Gu Changwei and Chen Sicheng.

　　Director Zhang Yimou’s diligence and talent are obvious to all. Directed by Zhang Yimou and starring Lei Jiayin, Zhang Guoli, Yu Hewei and Zhou Dongyu, As Hard as a Rock has been "waiting to be released" by the audience. The film tells the story of an ordinary young policeman who works in the criminal identification center of the municipal bureau. In order to protect the safety of the people, he started a thrilling investigation trip. This is the first time that director Zhang Yimou has directed an urban gangster film. The film has replaced the traditional classical composition with a modern shooting style. In the play, director Zhang Yimou will present crime and humanity with fresh handwriting.

　　Gu Changwei, who is also the "fifth generation" of director Zhang Yimou, also has a new work "Hedgehog" coming soon. The film, starring Ge You and Karry, is adapted from Zheng Zhi’s short story "Fairy Disease", which tells the story of Wang Zhantuan and his nephew Zhou Zheng, a strange couple who forgot to make friends. They are "heterogeneous" in the secular world, but they are normal people in each other’s eyes, and they have experienced a unique absurd past in Northeast China.

　　"Hedgehog" was finished on January 19th this year, and Ge You played the role of the earthly man Wang Zhantuan, trying the role of a mental patient for the first time. Karry subverts the image and plays the self-abased and stuttering teenager Zhou Zheng. In the previously released trailer, the lens came to an abrupt end with Wang Zhantuan’s sentence "You are not sick", which was thought-provoking. Is there a "disease" how to define it? Where does the so-called "disease" come from and how to recover? Northeastern dialect dialogue with its own sense of joy is matched with spicy human inquiry, showing a unique black humor. The beginning of the film makes people wonder how director Gu Changwei will tell this story.

　　It is worth mentioning that the filming of Hedgehog is the re-cooperation between Ge You and Gu Changwei after Farewell My Concubine for nearly 30 years. Gu Changwei’s works attach importance to humanistic care, and look at the bottom groups of society. As a favorite actor, Ge You’s comedy style can often add bright colors to heavy themes. When Gu Changwei’s humanistic spirit collides with Ge You’s comedy characteristics, it is expected that generate will have a wonderful chemical reaction.

　　Another comedy, Mozart in Outer Space, is also eagerly awaited. It is a sci-fi and comedy film written and directed by Chen Sicheng and starring Bo Huang and Rong Zishan. The film tells the story that Ren Dawang (Bo Huang) is bent on cultivating his son Ren Xiaotian (Rong Zishan) who likes astronomy into a piano player, and the mysterious alien Mozart helps Xiaotian and his father start a life of wits and courage after his unexpected appearance.

　　Chen Sicheng plans to create a cute king who has influenced generations like Doraemon through this film and become an "outer space trilogy". The film was released at the end of 2020, but it was not released in the summer of 2021 because the post-production stage exceeded expectations. It is speculated that the film may be released this summer.

　　Text/reporter Xiao Yang Coordinator/Liu Jianghua