At the press conference held by the Ministry of Transport today (25th), Wang Tai, deputy director of the Highway Bureau of the Ministry of Transport, said that since the 18th National Congress of the Communist Party of China, the scale of China’s highway infrastructure network has been among the highest in the world, and the transportation service support capacity has been continuously improved, making it easier for people to travel, which has strongly supported economic and social development and the improvement of the country’s comprehensive strength.

　　The National Highway Network Plan released in 2013 proposes that by 2030, the total scale of China’s national highway network will be about 400,000 kilometers, of which the total scale of national highways and ordinary national highways will be 136,000 kilometers and 265,000 kilometers respectively. Through the efforts of all parties, by the end of 2021, 117,000 kilometers of national highways had been built, and the mileage of ordinary national highways was 257,700 kilometers, with the completion ratio reaching 85% and 96.5% respectively.

　　First, the network coverage is more extensive.At present, the expressway network with the national expressway as the main body has covered 98.8% of the cities with a population of more than 200,000 and prefecture-level administrative centers, connecting about 88% of the county-level administrative regions and about 95% of the population; Ordinary national highways basically cover administrative regions at or above the county level and border ports opened all the year round, effectively connecting important towns, industrial parks, transportation hubs and tourist attractions.

　　Second, the level of facilities has been effectively improved.By the end of 2021, the proportion of national highways with two-way six lanes and above will be 20.9%, and a large number of busy sections of national highways such as Beijing-Harbin, Beijing-Shanghai, Beijing-Hong Kong-Macao, Shenhai and Shanghai-Kunming will be expanded and rebuilt, and the service guarantee capacity of national highway backbone channels will be further improved. The proportion of national ordinary national highways of Grade II and above is 79.6%, which is about 10% higher than that in 2013. More than 98% of the roads have been paved with asphalt or cement concrete, which is about 13% higher than that in 2013.

　　Third, major projects continued to advance.The world-famous Hong Kong-Zhuhai-Macao Bridge was opened in October 2018, becoming a super cross-sea project integrating bridges, islands and tunnels. The Beijing-Xinjiang Expressway, which passes through the desert Gobi no man’s land, runs through the whole line, becoming another big passage in and out of Xinjiang after Lianhuo Expressway. Construction of Tianshan Shengli Tunnel on Urumqi-Yuli Expressway, which is more than 22 kilometers, started, constantly setting a new world record for expressway tunnels.

　　The fourth is to achieve breakthroughs in technological innovation.The highway survey and design technology represented by digital map, geological remote sensing, computer-aided design and simulation, and Beidou system application has made continuous progress. The technology of highway construction in soft soil, loess, frozen soil and desert areas is constantly maturing and improving, and the structure and material technology of highway pavement have withstood the double test of time and heavy traffic. Breakthroughs have been made in technologies and equipment related to super-long-span bridges, super-long tunnels in mountainous areas, submarine immersed tunnels and large-diameter shield tunnels, and "China Road, China Bridge and China Tunnel" have become beautiful business cards.

　　(CCTV reporter Tang Ying)

　

While affirming that Guangdong Province attaches great importance to the high-quality development of the pharmaceutical industry, the audit findings also point out that many pharmaceutical consumables distribution enterprises have increased intermediate sales links and raised the price of medical equipment, medical personnel have long accepted the benefits from pharmaceutical companies, and medical institutions have illegally purchased or used medical equipment.

Reporter | Qu Yixian

Source | vision china

On August 8th, an investigation report on special audit of People’s Republic of China (PRC) Audit Office (draft for comments) obtained by Economic Observer Network showed that three pharmaceutical manufacturers in Guangdong Province had used 4.077 billion yuan for public relations and other purposes, pushing up the ex-factory price of drugs.

In addition, while affirming that Guangdong Province attaches great importance to the high-quality development of the pharmaceutical industry, the audit findings also point out that many pharmaceutical consumables distribution enterprises have increased intermediate sales links and raised the price of medical equipment, medical personnel have long accepted the benefits from pharmaceutical companies, and medical institutions have illegally purchased or used medical equipment.

From the end of May to July, 2023, the audit team sent by the National Audit Office conducted a special audit investigation on the production, distribution and use of drugs and high-value medical consumables in Guangdong Province (excluding Shenzhen, the same below), focusing on the relevant administrative departments of drug supervision, medical security and health care in Guangdong Province, public hospitals, primary medical and health service institutions and other medical institutions, and the production and distribution enterprises of drugs and consumables.

People close to the Guangdong Health Care System told Economic Observer that the Guangdong Health Care System was indeed being audited some time ago and just ended. "This audit is very strict."

The above audit investigation report was signed by "Guangdong Provincial Special Audit Investigation Team on the Production, Distribution and Use of Drugs and High-value Medical Consumables", which was forwarded by the Guangdong Provincial Health and Health Commission Office to Guangzhou, Zhuhai, Foshan, Heyuan, Dongguan, Zhongshan Health Bureau (Commission), Provincial People’s Hospital, Provincial Second People’s Hospital, Third Affiliated Hospital of Sun Yat-sen University, Cancer Prevention Center of Sun Yat-sen University, Stomatological Hospital of Sun Yat-sen University, Southern Hospital of Southern Medical University, and Second Affiliated Hospital of Southern Medical University.

The staff of the above-mentioned hospital confirmed to the Economic Observer that the investigation report forwarded by the Guangdong Provincial Health and Health Commission was true. The doctor of another hospital told Economic Observer that the hospital level issued several anti-corruption announcements.

Drug production enterprises collect funds for public relations.

Audit spot checks found that from 2021 to May 2023, three pharmaceutical manufacturers in Guangdong paid fees to 1,936 third-party business promotion companies, and withdrew 4.077 billion yuan in the name of service fees, which increased the comprehensive cost of drugs and pushed up the ex-factory price.

These three enterprises are Guangdong Yifang Pharmaceutical Co., Ltd. (hereinafter referred to as "Guangdong Yifang Company"), Guangzhou Poinsettia Pharmaceutical Co., Ltd. (hereinafter referred to as "Guangzhou Poinsettia Company") and Livzon Group.

Among them, the Guangdong company paid 2.39 billion yuan to 966 business promotion companies in the name of "technical service fee", which was used for the pharmacy construction cost and labor cost of cooperative hospitals.

Guangzhou Poinsettia Company collected 1.675 billion yuan by registering conference service companies in batches, and assigned a third-party company to register and set up 962 conference service companies at the same address in the form of "cluster registration". The third-party company further decomposed the funds according to the requirements of Guangzhou Poinsettia Company and transferred them to specific personnel accounts to pay the public relations expenses of hospitals in various regions.

Livzon Group set up a consulting company through its employees to collect funds of 12.4001 million yuan, and the funds were transferred to the personal accounts of relevant employees for drug public relations.

In addition to pharmaceutical manufacturers, the audit investigation team also found that pharmaceutical consumables distribution enterprises increased intermediate sales links and pushed up the circulation price of medical equipment. The enterprises involved include Kangchao Pharmaceutical Co., Ltd. and Sinopharm Equipment (Dongguan) Co., Ltd., and the products involved include Cao Qinghua Yixin Chushi Zhitong Capsule and other high-value medical consumables such as spinal internal fixators.

It is worth noting that there are also public hospitals that increase procurement intermediate links to make profits to subordinate enterprises. For example, from 2020 to May 2023, the Cancer Hospital affiliated to Sun Yat-sen University appointed Guangdong Guanhua Medical Service Company, a subsidiary of the trade union, to supply medical consumables for it, and Guangdong Guanhua Medical Service Company made a profit of 7,488,200 yuan, with an average price increase rate of 6.6%.

Medical personnel have long accepted the benefits delivered by pharmaceutical companies.

Audit investigation shows that domestic authoritative medical experts have long accepted exclusive service arrangements of foreign-funded pharmaceutical enterprises. Kehui Medical Devices International Trade (Shanghai) Co., Ltd. (hereinafter referred to as "Kehui Company") is a wholly foreign-owned enterprise, which mainly sells Covidien brand medical devices, and has long sponsored academic exchange activities organized by medical and pharmaceutical associations at all levels in China, and requires domestic distributors to pay accommodation, transportation, air tickets and other expenses for participating doctors and experts according to 2% of annual sales.

The audit spot check found that in 2022, Foshan Tailing Trading Co., Ltd., the brand distributor, paid 15.8117 million yuan for transportation, accommodation, catering and other expenses for medical experts and related personnel through nine travel agencies according to the instructions of Kehui Company, of which only one travel agency provided special follow-up, special car transfer and gifts for 272 authoritative experts in the medical field in China (including 63 in Guangdong Province) in seven meetings.

In addition, 4,782 medical staff illegally accepted the benefits delivered by foreign-funded pharmaceutical companies in the name of conference registration fees, involving pharmaceutical companies such as Bayer Healthcare Co., Ltd.

In addition, four medical experts from public hospitals received a targeted donation of 2.37 million yuan from pharmaceutical companies through the foundation of Guangdong Medical Association, involving five pharmaceutical companies including Beihai Kangcheng (Shanghai) Biotechnology Co., Ltd.

Medical institutions illegally purchase or use medical devices.

The audit investigation found that medical institutions illegally purchase or use medical devices, which has hidden hidden dangers of life and health and financial security.

The audit spot check found that three medical institutions, including Zengcheng Branch of Southern Hospital of Southern Medical University (hereinafter referred to as Zengcheng Branch of Southern Hospital), had problems such as determining the winning bidder in advance and purchasing large-scale medical equipment at a high price, involving funds of 73.0828 million yuan (including equipment price increase of 30.209 million yuan).

For example, in 2020, the then president of Zengcheng Branch of Southern Hospital organized the head of the department to conduct a feasibility study on purchasing X-ray computed tomography scanner, and determined the equipment of American GE Company quoted by Guangzhou Tangyun Medical Equipment Co., Ltd. In June 2021, the enterprise actually controlled by the company won the bid with the same brand and model equipment, with the winning bid amount of 29.49 million yuan, the purchase price of which was 14.287 million yuan, and the difference reached 15.2 million yuan.

In addition, the audit survey found that from 2018 to May 2023, a total of 491 medical institutions in Guangdong Province entrusted Guoyi Tendering Co., Ltd. to carry out bidding for more than 10,000 large-scale medical equipment or consumables procurement projects, with a total project amount of 22.386 billion yuan. Among them, only 3 companies participated in the bidding for nearly 9,000 projects.

Zengcheng Branch of Southern Hospital illegally purchased a proton radiotherapy system equipment without the permission of National Health Commission Class A large-scale medical equipment configuration, and paid 50% of the purchase price of 120 million yuan from the special government debt before the main components were shipped.

In terms of illegal use of medical devices, two medical institutions, including Zhongshan People’s Hospital, repeatedly used 2409 disposable ultrasonic blades, involving 15,100 person-times, involving medical insurance fund of 7,730,600 yuan. The Stomatological Hospital of Southern Medical University applied the "ultrasonic osteotome" used in the operation to the charging item of "additional ultrasonic scalpel", and illegally charged 67.2031 million yuan for medical treatment and 5.7011 million yuan for medical insurance fund.

The audit investigation also found that Guangdong Medical Association received 52,056,200 yuan from 329 pharmaceutical companies to designate doctors to promote their products. Guangdong Medical Association fraudulently distributed lecture fees and preparation fees of 169,600 yuan to medical experts in violation of regulations.

It is worth noting that the audit survey results also pointed out that Guangdong Province attaches great importance to the high-quality development of the pharmaceutical industry, actively promotes comprehensive reforms in the pharmaceutical field, and continuously optimizes the business environment of pharmaceutical enterprises, achieving good results. In view of the problems found in the above audit investigation, the audit investigation team also gave a number of suggestions.

On August 8, Economic Observer Network called the investor relations department of Livzon Group several times, but it was not connected. Ask Bayer China for an interview and get no reply; The relevant person in charge of Beihai Kangcheng responded that his company had not received a notice to cooperate with the investigation, and it was not clear about the specific situation.

Original title: Medical Corruption in an Audit Investigation Report

Read the original text

Full of green’s parks, greenways, clean and tidy farmers’ markets, neatly parked roadside vehicles and colorful volunteer activities … Walking in Longgang, the civilization scene everywhere is refreshing.

The beauty of the city is not limited to the beautiful scenery, but also lies in the profound and heavy background of civilization. In the three years since the town was removed and the city was set up, in the hot spot of reform, the projects of upgrading quality and improving people’s livelihood have been accelerated: more than 30 hectares of green space have been added, and 7.2 kilometers of greenways for people’s livelihood have been completed; Create 4 Wuhua farmers’ markets and 9 provincial assured markets; Get through the microcirculation of regional roads, and traffic congestion has dropped significantly …

Today, Longgang is making great efforts to move towards a provincial demonstration civilized city.

"external beauty"

Dress up the value of the city based on the existing resources

Uniformly decorated interiors, standardized and tidy booth classification, and strict garbage management … The fourth vegetable market in Longgang City is a clean and hygienic modern farmer’s market. "After the management reform in recent years, the environment of the vegetable market has changed too much." Ms. Zhu, a business owner who has been engaged in aquatic products for 20 years, deeply felt: "With the red, yellow and green OEM, we will know where to start improving."

Previously, the Longgang farmers’ market generally had problems such as dirty environment and outdated equipment, and the basic conditions were relatively weak. In order to solve the difficulties, Longgang has transformed the market as a whole in batches based on the original market framework through internal transformation and upgrading. At present, it has created 4 Wuhua farmers’ markets and 9 provincial assured markets.

After the market transformation and upgrading, how to maintain it is a big problem. To this end, Longgang further optimized the management mechanism by means of "green, yellow and red list" scoring mechanism and market professional management. The OEM mentioned by Ms. Zhu is the innovative practice of Longgang City. "We evaluate the farmers’ market and business households separately, and judge the green, yellow and red lists every month according to the scores, reward the winners of the green list, and take punishment measures such as suspending business and rectifying the objects on the’ red list’." Sun Zuogan, deputy director of Longgang State Administration for Market Regulation, said that they have also effectively implemented the main responsibility of the market and improved the market management ability through specialized custody of the farmers’ market.

While dressing up the farmers’ market, the traffic problems closely related to people’s livelihood are also quietly changing. Since July this year, the traffic micro-circulation construction has been implemented in the Xiakou area of Longgang, and 16 two-way paths in the area have been changed to one-way traffic, and on-street parking spaces have been added. As soon as this move comes out, it not only relieves the traffic pressure on main roads, improves the utilization rate of secondary and branch roads, but also relieves the contradiction between parking supply and demand to some extent. "In the case that the urban road reconstruction project is difficult to implement, it is an effective measure with little investment and quick results to carry out traffic microcirculation reconstruction." Lin Hao, deputy squadron leader of Longgang Traffic Police Brigade, said that since the trial, the traffic congestion alarm in Xiabu area has dropped by 80%, and the traffic accident alarm has dropped by 28.1%.

Strolling in the ecological corridor of Yuehu Lake and Cuihu Lake, the beautiful lakeside scenery and the scene of the new district with high-rise buildings are reflected in the curtain. From "beautiful corner" to "dotted", in recent years, Longgang has been deeply involved in the construction of park green space, relying on the renovation of Kugaji to further enhance the urban ecological charm. At present, 15 "Jinjiao Yinbian" park green space projects have been started, with more than 30 hectares of green space added, and 7.2 kilometers of greenway for people’s livelihood has been completed. The first phase of Yuehu Cuihu Ecological Corridor has been completed, and the second phase of the city park (wetland) park is scheduled to open in late September. By then, Longgang citizens will have more good places to rest and entertain.

"inner beauty"

Enriching cultural activities and condensing consensus on writing.

The most beautiful scenery of a city is "people", and the most beautiful scene is that everyone is bathed in the new wind of civilization and everyone is involved in the creation of civilization.

On the occasion of the Mid-Autumn Festival on September 10th, 13 families from Zhixinmingdu Community in Longgang spent an unforgettable full moon night together-tasting moon cakes, learning about Mid-Autumn Festival customs and folklore, and going to the seaside sightseeing belt to watch the tide and enjoy the moon. Under the leadership of volunteers, the scene was full of laughter and laughter, and everyone talked about the beautiful life and felt the romance and warmth of the traditional culture of Mid-Autumn Festival together.

This is a microcosm of Longgang’s rich volunteer service activities and the promotion of the construction of a 10-minute volunteer service circle. In recent years, with the transformation of Longgang from town to city, citizens have put forward new requirements for the content and quality of cultural services.

Based on the construction of a civilized practice center in the new era, Longgang established a voluntary service federation, launched a new form of voluntary service order, and opened up the "last mile" of serving the masses. Through the online platform, communities and citizens can submit the demand for activities, and the system accurately delivers the orders to professional teams in the form of dispatching orders, thus achieving accurate delivery of volunteer activities. As of August this year, Longgang has carried out more than a thousand voluntary service activities. Quietly, the power of civilization imperceptibly infiltrated the hearts of Longgang citizens.

Taking the creation of "Sharing Society Happiness Lane" as the starting point, Longgang actively builds a 15-minute quality cultural life circle and accelerates the construction of cultural activity facilities. A number of key cultural sites with high value and high taste, such as Longgang Art Museum, Yue Long Road City Study Room, and Jiajiao Lacquerware Private Museum, have successively landed.

"The creation of a civilized city is a systematic work, which depends not only on the government’s leadership, but also on the participation of the masses." Huang Changyao, deputy director of the Propaganda and United Front Work Department of Longgang Municipal Committee, said that in order to unite the consensus of creating articles, Longgang focused on the improvement of the exquisite environment in the whole region, promoted the creation of civilized cities, strengthened the construction of the creation mechanism, and established a centralized action plan, a centralized inspection plan, and a civilized "1151" system to create linkage mechanisms. At the same time, it also created Tuesday Civilization Creation Day, monthly volunteer service festival, daily courtesy zebra crossing persuasion and other activity carriers to promote the creation of civilization throughout the world.

Walking in Longgang, wherever you go, the flowers of civilization bloom-every courtesy in front of the zebra crossing, every time you bow your head and pick up the garbage around you, and every smiling face of volunteers is a beautiful interpretation of the broad masses of cadres and people in the city who have devoted themselves to the creation of provincial civilized cities.

If you do not stop, the future can be expected. With the joint efforts of the whole city, the upsurge of creating a civilized city is surging in Longgang, and a picture scroll of butterfly change of civilization showing the characteristics of Longgang is slowly spreading out.(Reporter Jin Ruiya)

New expectations of citizens

Yellow light shuttle

Identity:

Secretary of the Party Branch of Xipai Community in Longgang

Voice:

With the promotion of the establishment of a civilized city, in recent years, the appearance of Longgang farmers’ market has changed completely. In particular, our Xipai Farmers’ Market, as the first five-star standard pilot in our city, has completed the five-star drawing design at present, and will immediately start the budget, bidding and other processes, design and build according to the five-star standard, so as to obtain the acceptance of the four-star civilized and standardized market this year, declare the establishment of the five-star civilized and standardized farmers’ market next year, and strive to create the first five-star civilized and standardized farmers’ market in our city.

link

Frontier science issues

What is the ecological mechanism of cross-species transmission of coronaviruses?

　　At present, COVID-19 is raging around the world. Virologists have repeatedly warned that cross-species transmission of coronaviruses is a high probability event. The background situation of wild animals such as bats carrying coronaviruses and how wild animals break through ecological and physiological barriers to cause cross-species transmission and infection are still unclear at the scientific level. This question is of great significance for revealing the cross-species transmission mechanism of coronaviruses and preventing future epidemics caused by coronaviruses.

Question 2: How will the attractive force wave reveal the mysteries of the universe?

　　Since the first direct detection of attractive force waves in 2015, attractive force waves have rapidly become a hotspot in the frontier research of basic physics and astrophysics in the world, and it is expected that there will be a historical opportunity for major breakthroughs in the origin of the universe in more than ten years. Attractive force waves open a new window for observing the universe. By observing the generation and distribution of attractive force wave sources in the universe, it is expected to answer the deep scientific questions left over from the standard model of general relativity and particle physics, thereby deepening the understanding of nature.

Question 3: How does Earth’s material evolve and circulate?

　　The earth’s materials are mainly divided into rocks and minerals. People’s understanding of the evolution and circulation of magmatic rocks and metamorphic rocks in the earth’s historical period is blurred due to the lack of comprehensive analysis of big data. Using the comprehensive analysis of big data platforms and deep-time big data systems on the earth, it is possible to establish a connection between the basic course and special events of mineral evolution and planetary geological evolution, clarify the evolution law and coupling relationship of planetary earth and its multiple circles from the perspective of mineral evolution, and answer the basic scientific questions about how planetary earth evolves and whether there is a co-evolution relationship between various circles of the earth.

Question 4: What will a fifth-generation nuclear energy system look like?

　　In 2000, the Fourth Generation Nuclear Energy System International Forum initiated by the US Department of Energy divided the development of nuclear energy into four generations. At present, the research on the fifth generation nuclear energy system is still in the exploratory and exchange stage, and there is no mature concept definition and goal definition, and there is little talk about its realization path. If it can promote the implementation and final realization of the concept of the fifth generation nuclear energy system, it can reform the concept of nuclear energy development, the model of nuclear energy development, the concept of nuclear energy application, and support the deep decarbonization of the energy system; lead the world in nuclear energy innovation, and help China become the world’s nuclear energy innovation highland.

What is the scientific principle of special energy field-assisted manufacturing?

　　With the continued demand for lightweight and safety in aerospace, transportation, and other fields, high-strength materials, including ultra-high-strength steels, light alloys, composites, and intermetallic compounds, are applied to complex components. As material strength increases, manufacturing difficulty increases significantly, and forming defects are more difficult to control. Existing research shows that special energy field-assisted forming technology has great potential in improving the manufacturing challenges of high-strength and difficult-to-deform materials.

Question 6: How can digital transportation infrastructure promote the coordinated development of autonomous driving and vehicles?

　　In the future, the large-scale social operation of autonomous vehicles will inevitably appear, which will be a change for the transportation system, and the road transportation system is facing the challenge of evolution and replacement. For the research on new road infrastructure to support the social operation of autonomous driving, our country is still in its infancy, and there is no ready-made advanced technology and experience abroad to learn from. It is necessary to transfer the support of autonomous driving research to the research of intelligent supply on the infrastructure side and the research of comprehensive integrated landing application in a timely manner.

Question 7: What is the mechanism of traditional Chinese medicine that regulates human immune function?

　　Although the basic research of immunology has made remarkable achievements and medicine is also developing by leaps and bounds, it is still insufficient in the prevention and treatment of many difficult and serious diseases. Autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, and ankylosing spondylitis still plague patients. The occurrence, development, and outcome of these major and difficult diseases are closely related to immunity. Traditional Chinese medicine can act on the body at multiple levels, targets, and pathways, regulate the body’s immune function, and has important application value in disease prevention and treatment.

Question 8: What is the biological basis of plant apomixis?

　　Non-fusion reproduction is a kind of reproductive method that propagates asexually through seeds, which can make hybrid varieties produce cloned seeds, keep the characters of hybrid offspring from separating, and thus permanently fix ** advantages. However, due to the complexity of the mechanism of non-fusion reproduction, despite the efforts of scientists from many countries for nearly a century, its formation mechanism is still unclear, and it has not been successfully applied to crop breeding.

Question 9: How to optimize the water carrying capacity of our country in a changing environment and achieve a healthy regional water balance?

　　At present, the construction of ecological civilization in our country has entered an accelerated period and a critical period, which puts forward higher requirements for the intensive utilization and strict protection of water resources. Studying the scientific issue of water resources carrying capacity and water balance optimization under changing conditions is conducive to deepening the understanding of the factors of regional water cycle in our country and their evolution laws, improving the evaluation method of water resources carrying capacity, clarifying the index significance of water balance status for water resources carrying capacity, clarifying the occurrence mechanism of many water problems and ecological environment problems, and providing important theoretical and technical support for summarizing the economic and social development and ecological protection models that are compatible with water resources carrying capacity, and effectively protecting and restoring the ecological environment.

Question 10: How to establish a theoretical and technical foundation for virtual twins and develop demonstration applications?

　　Virtual twin is a process and method for describing and modeling the characteristics, behavior, formation process and performance of physical entities and intelligent entity objects in the real world using digital technologies such as sensors, Internet of Things, virtual reality, artificial intelligence, etc. on the basis of digital twin, also known as virtual twin technology. It is based on digital twin, but focuses more on modeling and simulation of intelligent entities or living beings. How to realize the interaction and integration of manufacturing the physical world and the information world is one of the core bottlenecks currently faced by the practice of intelligent manufacturing concepts and goals at home and abroad.

Engineering problems

Question 1: How to develop new pathways and technologies for novel immune cells in tumor treatment?

　　Immune cell technology is the hope for human to completely cure tumors, and it is one of the hot areas pursued by cutting-edge medicine and capital around the world. As a key node cell linking cellular immunity and humoral immunity, dendritic cells (DC) can mobilize the entire immune system, resist the invasion of pathogens and promote the clearance of tumor cells, becoming a key research direction of new immune cell therapies. The new DC amplification technology can realize the standardization and mass production of DC vaccines, which can significantly reduce the preparation cost and serve more cancer patients, with obvious economic and social benefits.

Question 2: Why has the integrated design of horizontal take-off and landing combined power vehicles become the new focus of aerospace technology?

　　水平起降组合动力运载器具有快速、廉价、可靠的特点，可成为低成本天地往返运输工具。水平起降组合动力运载器一体化设计技术是支撑未来航天运输系统发展与应用的核心技术之一，是未来先进航天运输系统的重要支撑技术之一。

●问题3：如何实现农业重大入侵生物的前瞻性风险预警和即时控制？

　　农业有害生物入侵不仅仅是简单的植物病虫害或动物疫情问题，入侵生物的发生流行不仅危害食品安全和农业生产，造成巨大的直接经济损失，还可能对人类健康构成越来越大甚至是灾难性的威胁，对外交、经济和社会产生巨大影响。因此，站在国际化、全球化视角，从科学研究和专业技术层面，开展农业入侵生物跨境传播预警及防减技术合作的协同攻关，将有力解决入侵生物疫情的源头治理和联防联控关键技术难题，保障社会稳定与公共安全。

●问题4：信息化条件下国家关键基础设施如何防范重大电磁威胁？

　　强电磁脉冲一旦对金融、能源、电力等领域的关键信息基础设施产生影响，将可能导致交通中断、金融紊乱、电力瘫痪等重大事故。开展此项研究，对确保关键基础设施电磁安全、保护经济建设成果、提升关键基础设施容灾抗毁能力具有重要意义。

●问题5：硅光技术能否促成光电子和微电子的融合？

　　信息光电子芯片已然成为“数字化新基建”的核心和基石，也是全球信息通信价值链的关键领域和网络强国建设的“国之重器”。硅基光电子芯片技术既可应用于芯片级光互连，又适用于长距离光纤通信，可实现全功能光电子集成，具有极高的通用性和兼容性，是微电子和光电子两大产业公认的发展方向。利用国内现有微电子产业资源和互补金属氧化物半导体（CMOS）制造平台，建立健全硅光产业链，可以有效提升我国信息光电子的制造能力，缓解光电子芯片制造工艺的“卡脖子”困境，为我国信息化新基建提供有力支撑。

Question 6: How to solve the problem of on-line defect detection in integrated circuit manufacturing process?

　　The field of integrated circuits is currently the main battlefield of international science and technology competition and the focus of the game between major powers. For integrated circuit defect detection technology and equipment, on the one hand, the most advanced technology and equipment are monopolized by a few developed countries; on the other hand, the defect online detection technology of 7 nanometers and below nodes around the world is still immature, and the equipment gap is still huge. Whoever takes the lead in mastering the corresponding key technologies will have the dominance in the future. This is both an opportunity and a challenge for our country.

Question 7: How can unmanned vehicles achieve high-precision intelligent navigation under conditions where satellites are not available?

　　Special unmanned vehicles represented by unmanned rescue vehicles, unmanned mining vehicles, and unmanned transport vehicles are the core unmanned equipment for completing modern operations, emergency rescue and disaster relief. In order to improve the emergency rescue and joint operation capabilities of unmanned vehicles, its navigation system is required to have functions such as high-precision positioning, autonomous obstacle avoidance, intelligent path planning and guidance. Therefore, it is necessary to study high-precision and fully autonomous navigation methods and to solve the problem of inertia-based intelligent navigation for unmanned vehicles.

● Question 8: How to achieve the unity of "large-scale", "low energy consumption" and "high stability" in the large-scale production of hydrogen by electrolysis of water from renewable energy sources?

　　The development of high-efficiency and low-cost renewable energy and hydrogen energy technologies is a timely response to the country’s major needs, and it is also a high-quality solution for reducing carbon emissions and mitigating climate change globally. However, the current level of development of hydrogen electrolysis technology limits the conversion efficiency and industrialization process of renewable energy into chemical energy. Breakthrough in high-efficiency, low-cost, and large-scale hydrogen electrolysis technology can greatly promote the utilization and development of renewable energy and hydrogen energy.

Question 9: How to break through the intelligent construction and engineering health protection technology of the expressway into Tibet?

　　The lithology of the Qinghai-Tibet Plateau is complex and changeable, the neotectonic movement is intense, the deep and large active faults are widely distributed, the glaciers, permafrost and mountain disaster groups (chains) are developed, and there are "significant terrain height difference", "strong plate activity", "frequent mountain disasters", "sensitive permafrost environment" four geological environmental characteristics, as well as "high frequency freeze-thaw cycle", "severe wet and dry alternation" and "extreme cold and hypoxia" three climatic and environmental characteristics. The series of engineering and technical problems brought about by this are the key technical factors restricting the development of high-speed transportation in Tibet.

　　Rise to the sea, set sail and compete for first class. Since 2012, it has been a decade of passionate progress in Daya Bay, and it has been a decade of pioneering exploration in Daya Bay. Daya Bay bravely undertakes the mission and strives to build a domestic first-class development zone with high quality; Carry forward the great spirit of party building, strengthen historical self-confidence, keep in mind the initial mission, comprehensively promote the overall layout of the "five in one", work hard, focus on solving new development problems, and strive to write a new chapter in sustainable development and improving people’s livelihood and well-being.

　　From 40 billion yuan to 80 billion yuan, Daya Bay has reached four 10 billion yuan steps in ten years. In 2021, the GDP of the whole region reached 80 billion yuan, with a cumulative increase of over 85% in ten years; The added value of industrial enterprises above designated size was 53.33 billion yuan, a cumulative increase of 101.5% in ten years; The total tax revenue of the whole region (including tax collected by customs) was 50.46 billion yuan, with a cumulative increase of 67.4% in ten years; In the past ten years, the total investment in fixed assets in the whole region has reached 310.31 billion yuan, with an average annual investment of 31.03 billion yuan …

　　Groups of data are the imprint of Daya Bay’s solid steps in accurately and comprehensively implementing the new development concept. Nowadays, Daya Bay, which is sailing for the sea, is seizing the great opportunity of "two-zone" construction, building a world-class green petrochemical industry highland with high quality, and striving to become an important supporting area for Huizhou to build a happier domestic first-class city.

Daya Bay firmly adheres to the road of ecological priority and green development.

　　Entering Daya Bay, key national, provincial and municipal projects such as ExxonMobil Huizhou Ethylene Project and Hengli (Huizhou) PTA Project are in full swing. On the other side of Huizhou Port, ships enter and exit, and vehicles shuttle; In the newly planned 100 billion-level Daya Bay Emerging Industrial Park, the production line of Zhouming Technology Daya Bay Science and Technology Park, the world’s largest intelligent LED display base, is running rapidly; Wanda Commercial Circle, Canbang Plaza and Yitian Commercial Circle are three pillars, with towering high-rise buildings, various commercial centers and vigorous consumption … With the rapid economic and social development of Daya Bay in the past 10 years, a new coastal city with integrated development of production, life and ecology has taken shape, and the future can be expected.

　　On November 8, 2021, ExxonMobil announced its investment decision to the world, and increased the first phase of total investment of the project from $5.5 billion to $6.7 billion. With the construction of the project, ExxonMobil Asia-Pacific R&D Center has also settled in Huizhou, which shows the confidence and determination of this oil and gas giant to invest in Daya Bay.

　　In recent years, in the face of the COVID-19 epidemic and the complicated and severe challenges of the domestic and international economic situation, Daya Bay District has continuously optimized its business environment and promoted the construction of major projects at an extraordinary speed. Investing in the development of highland has become a new label of Daya Bay, and leading enterprises in Chinese and foreign industries are coming in droves. According to statistics, in recent years, 129 foreign-invested enterprises (projects) have been newly established in total investment of the project, amounting to 7.16 billion US dollars.

　　Sharpen a sword every ten years. Today, Daya Bay has become one of the seven national petrochemical industrial bases, and Daya Bay Petrochemical Zone has topped the top 30 chemical parks for three consecutive years. Daya Bay has gradually formed the orientation of "attracting large investment, attracting large businesses and developing greatly" in the development of economy, and has drawn a "investment map" of high-quality projects that are helpful to extend, supplement and strengthen the chain.

　　In recent years, Daya Bay District has made precise investment promotion around the industrial chain and further improved the "Investment Promotion Map". A set of investment project evaluation system consisting of 15 rigid quantitative indicators has been translated into English, Korean and Japanese, which has become a "hero post" for investment promotion issued by Daya Bay District to the world.

　　Keeping a close eye on the world’s top 500 enterprises and leading enterprises in the industry, Daya Bay gives full play to the leading role of leading enterprises such as CNOOC, China Shipping Shell, ExxonMobil, Hengli PTA and Guangzhao Lubricant, and conducts business attraction and investment promotion in the industrial chain, focusing on extending, supplementing and strengthening the chain. For example, China Merchants in Daya Bay said that the PC/DPC project of China Shipping Shell will become the only PC project in South China after it is completed and put into operation, forming a highly competitive PC industrial chain and leading the development of the C2 industrial chain. The third phase ABS project of Lejin Chemical will become the largest ABS production base in South China after it is completed and put into operation, and will continue to expand into a long C4 and aromatics industrial chain.

　　The advantages of these large projects are highly consistent with Daya Bay’s concept of building a world-class petrochemical industry highland and adhering to safe and green development, and are also a true portrayal of Daya Bay’s practice of high-quality and green development concepts.

　　The petrochemical industry has made precise efforts, and emerging industrial parks are also a thriving atmosphere. This vibrant park has attracted businessmen from the United States, Japan, Taiwan, China, Hong Kong, China and other countries and regions. At present, more than 100 projects have been settled, with a total investment of over 30 billion yuan. Well-known enterprises include BYD, Dongfeng Honda, Guanghong Technology, Sumitomo Forging, Xinlitai, Zhouming Technology, etc. The electronic information and auto parts industry has begun to take shape. "In the past ten years, with the vigorous development of Daya Bay, Guanghong Technology has made remarkable achievements." The person in charge of Guangdong Guanghong Technology feels that the progress of Guanghong in the past ten years is the best proof of Daya Bay’s development, from the upgrading of processing to intelligent manufacturing, and now it ranks among the high-quality listed companies.

　　"In the past ten years, the changes in the urban appearance of Daya Bay are amazing!" A senior media reporter spoke the voices of many people.

　　In Daya Bay Mangrove City Wetland Park, the plank road is clean and tidy; In the modern office building, energetic engineers are brainstorming; As night falls, the major shopping centers in the city are very busy … In the past ten years, the energy level of Daya Bay city has been continuously improved and the quality of the city has been constantly refreshed.

　　"Urban management should be as delicate as embroidery". Since the beginning of this year, the value of the entrances and exits of toll stations in Daya Bay has been higher, and the greening along the roads at intersections has become more exquisite, especially at night, with bright lights and charming scenery. These changes benefit from the implementation of the pilot project of upgrading urban quality nodes in Daya Bay District. With the issuance and implementation of the Construction Plan for Key Construction Projects in Daya Bay in 2022, Daya Bay District will carry out wall chart operations on 32 key construction projects, involving 6 road traffic projects, 9 industrial supporting projects, 8 human settlements projects, 7 people’s livelihood security projects and 2 flood control and drainage projects.

　　In order to comprehensively improve the urban quality of Daya Bay, Daya Bay has learned from domestic advanced urban management experience and practices, and carried out pilot projects to improve urban quality nodes throughout the region. This project includes the disc quality improvement project of Daya Bay West Area, the quality improvement project of Zhongxing South Road (Zhongxing Middle Road-Zhongxing Fifth Road Section), the elevation renovation project of Songtao Road (Xiaojingwan Toll Station-Shihua Avenue Section), and the quality improvement project of the entrances and exits of five high-speed toll stations such as Xiaojingwan Toll Station. The main facilities include the quality improvement of sidewalks and greening projects, and the lighting project of night scenes. The reporter learned from the Daya Bay Municipal Garden Management Office that the quality improvement project of each node in the project has been basically completed and the finishing work is underway.

　　Daya Bay will carry out the second phase of the urban quality node upgrading project this year, which will upgrade the quality of seven nodes, including Ximenlou of Shihua Avenue, Zhongxing Middle Road (Zhongxing South Road-Shugang Avenue) and Longshan No.1 Road (Longhai No.1 Road-Longhai No.3 Road). The main contents include pavement replacement, green belt combing, tree replacement and relocation, turf laying, micro-topography construction, and lighting engineering renovation and upgrading along the line.

　　It is understood that among the key construction projects in Daya Bay in 2022, there are eight residential environment projects, including Daya Bay Binhai Bidao and Landscape Construction Project (from Baguang to Fisherman’s Wharf), Daya Bay Lion Mountain Park Phase I Construction Project, Daya Bay West Old Community Reconstruction Project, Daya Bay Aotou Old Community Internal Quality Improvement Project, Daya Bay Aotou Old City Intelligent Parking Project and Daya Bay Second Water Purification Plant Phase III Project, etc. These projects are all being accelerated according to the set time nodes.

　　In order to improve the quality of the city, seize the opportunity of the times and practice high-quality development, Daya Bay has compiled the Urban Landscape Planning and Overall Urban Design of Daya Bay. "Overall Urban Design" has built an overall development pattern of "two mountains, one sea, five corridors and one network", cultivated a new platform for urban development at the level of business cards, improved the level of urban public service facilities, and improved public service facilities such as education, medical care, parks, culture and commerce.

　　There are more and more park squares around the people. In recent years, Daya Bay combines natural ecological conditions, with Tieluzhang and Bijiashan as the background mountains, Xiangshui River, Banzhangling, Hutou Mountain, Luoling and Mangrove as the core, Pingshan River and Dan ‘ao River as the main axes, featuring the coastal green spaces of Xiayong and Houzai Bay, and connecting with each other through the urban road greening system, forming a complete, rich, reasonable and urban green space system. At present, a large number of parks and squares, such as Banzhangling Park, Mangrove Urban Wetland Park, Hutoushan Park, Binhai Park, Fisherman’s Wharf, Huimin Square, Haiyun Square and Gold Coast, have met the leisure and recreation needs of residents.

　　In terms of commercial facilities, according to the layout idea of point, line and area, a large number of commercial complexes such as Wal-Mart, wanda plaza, Yitian Holiday Plaza, Canbang City Plaza, Century City Shopping Mall and Longguang Commercial Plaza have been built one after another along the main roads of the city, and citizens’ consumption experience is getting better and better.

　　In recent years, with the promotion of special rectification of municipal facilities, Daya Bay District has effectively improved the green environment of parks such as primary and secondary roads, kerbs, sidewalks, street lamps, Huimin Square, mangrove parks and coastal parks in accordance with the requirements of "purification, beautification and lighting", and the urban landscape has been continuously beautified. At the same time, improve the rapid response mechanism and the maintenance and acceptance mechanism of municipal facilities and landscaping, improve the traffic microcirculation, and make the management and operation of municipal facilities more smooth and effective.

　　Daya Bay District fully implements the responsibility system of "three guarantees in front of the door", implements three-level supervision, and includes "three guarantees in front of the door" in the annual inspection and assessment. At the same time, take the mechanism of creating civilized cities such as "hand-to-hand shooting" as the starting point to carry out rapid supervision and response.

　　A series of refined management has brought citizens and tourists a sense of identity and reputation for Daya Bay.

　　The water is clear and the banks are green, and gulls and herons fly in pieces. After ten years of renovation, the Tam O River has become a good place for citizens to relax.

　　"In the past ten years, the deepest feeling is that Daya Bay’s economy has developed, the city is more beautiful, and the ecological environment is better." In the past ten years, Daya Bay District has adhered to the concept of "Lucid waters and lush mountains are invaluable assets", unswervingly followed the road of ecological priority and green development, and strived to form a spatial pattern, industrial structure, life and production mode of saving resources and protecting the environment. The air quality has been ranked in the forefront of all counties and districts in the city for many years, and "good mountains, good water and good air" is becoming a beautiful business card for Daya Bay District.

　　The policy of paying attention to eco-environmental protection makes the green industry stimulate lasting and abundant development momentum, and the beautiful environment makes the green lifestyle a regional green trend. In Daya Bay Petrochemical Zone, the positive and negative list system is implemented for the EIA approval of projects entering the park, and all those that do not meet the requirements of industrial policies, relevant norms and energy conservation and emission reduction will be rejected by one vote; Take the lead in realizing full coverage of ecological towns and villages in the city.

　　Today, the east, west and north sides of the petrochemical area are wrapped by 2.33 million square meters of green isolation belt. The park is also sky-blue and green. It is difficult to link this environment with the annual output of 22 million tons of oil refining and 2.2 million tons of ethylene, and the scale of refining and chemical integration is the first in China. Here, every production link adheres to the technologies and concepts of recycling, green and low-carbon, safety and environmental protection.

　　The high-end, intelligent and green development of petrochemical industry is a true portrayal of Daya Bay District actively practicing the "five development concepts". "Green water and green mountains" and "Jinshan Yinshan" are mutually integrated and win-win, which lights up the beauty of Daya Bay District.

　　Since 2017, Daya Bay Petrochemical Zone has been recognized by the National Development and Reform Commission as a key support park for recycling transformation of national parks, and by the Ministry of Industry and Information Technology as the first batch of national green manufacturing system construction demonstration parks and national new industrialized industrial demonstration bases; The correlation degree of circular economy industrial chain in the park is as high as 95%, and 100% enterprises in key industries have carried out cleaner production audit, and four centralized sewage treatment plants have been built.

　　Daya Bay District continues to maintain high investment in safety and environmental protection, and has increased investment in environmental protection for many years in a row. In recent years, it has explored the governance strategy of "controlling, reducing and supplementing", that is, controlling source pollution, reducing total emissions, and supplementing ecological shortcomings, so as to comprehensively resolve the impact of development on the environment; In the prevention and control of air pollution, four sets of automatic atmospheric monitoring stations were built to monitor 46 atmospheric characteristic factors for 24 hours, and the air quality in the whole region was monitored and released in real time.

　　From January to June, 2022, the comprehensive index of ambient air quality in the whole region was 2.31, an improvement of 12.8% over the previous year, and the excellent rate was 100%, an improvement of 3.3 percentage points over the same period of last year. The air quality ranked second in seven counties and districts in the city. All the 16 rivers in the whole region meet the requirements of water functional zones, with a compliance rate of 100%, and the water environment quality ranks second among the seven counties in the city. The water quality in the coastal waters remains good; The water quality compliance rate of drinking water sources is 100%; The forest coverage rate is 44.37%, and the per capita park green space is 18.5 square meters, which has achieved the goal of ecological civilization construction with bluer sky, clearer water, more beautiful city and happier people, and presented a beautiful picture in which man and nature live in harmony and the economy, society and ecological environment complement each other.

Since September, Nanjing Children’s Hospital has received nearly 400 cases of influenza, which ushered in a small peak of influenza treatment.

Recently, the National Health and Wellness Commission held a press conference, suggesting that with the cold weather, it is the epidemic season of respiratory infectious diseases. Wang Huaqing, chief expert of immunization program of China CDC, suggested that influenza vaccine should be vaccinated before the end of October.

He mentioned that vaccination is usually better before the flu epidemic season, and it is generally recommended to complete vaccination before the end of October. If the vaccination is not available before October for various reasons, the vaccination should be completed as soon as possible in the follow-up so that the effect of the vaccine can be better played. Because it takes about 2 to 4 weeks for the vaccine to have an effect.

How to choose the flu vaccine? Who should be vaccinated the most? Who doesn’t recommend vaccination? About 13 questions about influenza vaccine, Jiangsu CDC authorities answered questions-

Q1. Why should I get the flu vaccine?

Influenza is not a common cold, but an acute respiratory infection caused by influenza virus. According to the estimation of the World Health Organization, influenza can cause 3 million to 5 million severe cases and 290,000 to 650,000 respiratory diseases-related deaths worldwide every year. Vaccination against influenza is an effective means to prevent influenza and reduce influenza-related severe illness and death.

Q2. What are the types of influenza vaccines? How should I choose?

There are inactivated vaccines (including split vaccines and subunit vaccines), attenuated live vaccines and recombination vaccines. According to the components contained in the vaccine, it can be divided into trivalent and tetravalent influenza vaccines. Compared with trivalent influenza vaccine, tetravalent influenza vaccine strains have added a pedigree of influenza B. Inactivated vaccine was injected intramuscularly, and attenuated live vaccine was sprayed intranasally.

The influenza vaccines approved for marketing in China this year include trivalent inactivated vaccine, tetravalent inactivated vaccine and trivalent attenuated live vaccine. People aged ≥6 months can be vaccinated with trivalent or tetravalent inactivated vaccine, and people aged 3~17 can also choose trivalent attenuated live vaccine. For people who can be vaccinated with different types of vaccine products from different manufacturers, they can voluntarily vaccinate any kind of influenza vaccine, and there is no priority recommendation.

Q3. When should I get the flu vaccine?

Usually, the antibody can reach the protective level after 2~4 weeks of influenza vaccination. The time and duration of the annual peak of influenza activity are different in different parts of China. It is suggested that the recipients should be vaccinated with influenza vaccine one month before the influenza epidemic season. If the vaccination is not completed before the arrival of the epidemic season, it can be vaccinated throughout the epidemic season.

Q4. Where can I get the flu vaccine?

Influenza vaccines can usually be vaccinated in community health service centers or hospitals. Vaccination units may vary from place to place, so please consult the local health administrative department for details.

Q5. Who needs influenza vaccination?

People who are over 6 months old and have no vaccination contraindications should be vaccinated against influenza.

Combined with the epidemic situation of influenza and the prevention and control strategy of multi-disease prevention, the harm of influenza is reduced as much as possible, and the following key and high-risk groups are recommended to be vaccinated in time:

① Medical personnel, including clinical rescue personnel, public health personnel, health and quarantine personnel, etc.

② Older people over 60 years old;

③ people suffering from one or more chronic diseases;

(4) Vulnerable people and employees in gathering places such as old-age care institutions, long-term care institutions and welfare homes;

⑤ Children aged 6 ~ 59 months;

⑥ Family members and caregivers of infants under 6 months old;

⑦ Crowds in key places such as kindergartens, primary and secondary schools and supervision places.

Q6. Who can’t be vaccinated?

① Those who are allergic to any ingredients contained in the vaccine (including auxiliary materials, formaldehyde, cracking agents and antibiotics) or who have had a history of severe allergy to any kind of influenza vaccination are prohibited from vaccination;

② Patients suffering from acute diseases, severe chronic diseases or acute attacks of chronic diseases, as well as patients with fever, are advised to be vaccinated after recovery or stable control of their condition;

③ Patients with Guillain-Barre syndrome within 6 weeks after previous influenza vaccination are advised to be evaluated by doctors before considering whether to vaccinate.

It should be noted that the following populations are prohibited from receiving live attenuated vaccines:

① Persons with low immune function due to drug use, HIV infection and other reasons;

② Children and adolescents who have been treated with drugs containing aspirin or salicylic acid for a long time;

③ Children with asthma aged 2-4 years;

4 pregnant women;

⑤ Those with a history of Guillain-Barre syndrome;

⑥ Those who used antiviral drugs such as oseltamivir and zanamivir 48 hours before inoculation, or those who used palamivir 5 days before inoculation, or those who used balosevir 17 days before inoculation.

Q7. What should I pay attention to after influenza vaccination?

After vaccination, you need to stay in the vaccination unit for half an hour. If there is no abnormality, you can leave on your own. After returning home, pay attention to rest, eat lightly and avoid strenuous exercise. If there is any abnormal phenomenon, you can consult and report to the vaccination doctor and go to the hospital if necessary.

Q8. Why do you have to get the flu vaccine every year?

First of all, influenza virus is prone to mutation. The World Health Organization proposes the recommended components of influenza vaccine for the next epidemic season every year based on the results of global influenza surveillance, and the influenza virus strains targeted by influenza vaccines may be different in different years. Secondly, the immunity of influenza vaccination will gradually weaken over time. Therefore, in order to provide more effective protection, it is recommended to vaccinate against influenza every year.

Q9. Is it safe to get the flu vaccine? Are there any side effects?

Influenza vaccination is safe, but like other medical products, influenza vaccine may also have adverse reactions. The common adverse reactions of influenza vaccination include local reactions (redness, swelling, induration, pain, burning sensation, etc.) and systemic reactions (fever, headache, dizziness, lethargy, fatigue, myalgia, general malaise, nausea, vomiting, abdominal pain, diarrhea, etc.). These adverse reactions are usually mild, and usually disappear on their own within a few days, with few serious reactions.

Q10. Can people with egg allergy be vaccinated against influenza?

Egg allergy is not a taboo in People’s Republic of China (PRC) Pharmacopoeia (2015 and 2020 editions). The current pharmacopoeia stipulates that the content of ovalbumin in inactivated influenza virus vaccine should not be higher than 250ng/ dose, and the content of ovalbumin in split vaccine should not be higher than 200ng/ml. There is no description of attenuated live vaccine at present. The measurement of egg protein content in commonly used influenza vaccines in China shows that the highest content is not more than 140ng/ml. At the same time, foreign scholars’ research on the inactivated vaccine or attenuated live vaccine inoculated to those who are allergic to eggs shows that no serious allergic reaction has occurred. Therefore, egg allergy is not recommended as a taboo for influenza vaccination.

Q11. Won’t you get the flu after vaccination?

In most years, influenza vaccine has a good match with influenza epidemic strains and has good protection. However, there is also a certain probability that the strain of influenza vaccine does not match the epidemic strain, which further affects the protection effect of influenza vaccine. In addition, influenza vaccination can only prevent influenza caused by influenza virus, but can not prevent such symptoms caused by infection of pathogens other than influenza virus (such as parainfluenza virus, adenovirus, etc.).

Q12. Can I get the flu vaccine while using antiviral drugs?

Inactivated influenza vaccine can also be inoculated during the prevention and treatment of influenza antiviral drugs. Preventive or therapeutic use of anti-influenza drugs will affect the immune effect of attenuated live influenza vaccine, and it is not recommended to use both at the same time. If you have used any other vaccines or drugs, including over-the-counter drugs, please inform the vaccination doctor before vaccination.

Q13. Can the flu vaccine be vaccinated at the same time as other vaccines?

Inactivated influenza vaccine, other inactivated vaccines and attenuated live vaccines, such as enterovirus 71 vaccine, pneumococcal vaccine, herpes zoster vaccine, chickenpox vaccine, measles vaccine and DTP vaccine, can be inoculated in different parts at the same time.

There is limited research evidence that live attenuated influenza vaccine and other vaccines are vaccinated at the same time. After vaccination with live attenuated influenza vaccine, other live attenuated vaccines can only be vaccinated after an interval of more than 4 weeks. (Wang Tian)

Source: Xinhua Daily Intersection Point

天安门广场上，人民英雄纪念碑巍然矗立。错落有致的观众席拼成一幅“巨轮启航”的壮阔画面。在“巨轮”船首，中国共产党党徽熠熠生辉，党徽两侧，是醒目的“1921”“2021”金色字标。全国各族各界人士7万余人相聚于此，共祝中国共产党百年华诞！

庆祝中国共产党成立100周年大会上，最高领袖总书记发表重要讲话，铿锵有力的话语声中，一幅壮阔恢宏的“百年答卷”徐徐展开。

△2021年7月1日上午，庆祝中国共产党成立100周年大会在北京天安门广场隆重举行。这是国旗护卫队准备升旗。

“百年答卷”主题深刻鲜明。

“一百年来，中国共产党团结带领中国人民进行的一切奋斗、一切牺牲、一切创造，归结起来就是一个主题：实现中华民族伟大复兴。”最高领袖总书记的精辟论述，高度概括了中国共产党百年历史。

△独家V观丨最高领袖总书记：为中国人民谋幸福、为中华民族谋复兴是中国共产党的初心使命

犹记得2012年11月29日，当选中共中央总书记仅15天的最高领袖同志，与十八届中央政治局常委一起参观《复兴之路》展览时明确提出，实现中华民族伟大复兴，就是中华民族近代以来最伟大的梦想。

Since the 18th National Congress of the Communist Party of China, General Secretary of the Supreme Leader has put the distinct theme of "realizing the great rejuvenation of the Chinese nation" into all aspects of governing the country. Today, China’s GDP exceeds 100 trillion yuan, making it the second largest economy in the world. 98.99 million poor people in rural areas have all been lifted out of poverty and completely got rid of absolute poverty; Maintaining social harmony and stability for a long time and people living and working in peace and contentment have been praised by the international community as one of the most secure countries … …

Give an outline and read it, solve a volume and make it clear to all. The little "red boat" became a mighty "great ship", and after realizing the first century-long struggle goal, it continued to ride the wind and waves and sailed steadily to the second century-long struggle goal.

Great achievements in writing "Centennial Answers".

Focusing on the theme of realizing the great rejuvenation of the Chinese nation, General Secretary of the Supreme Leader comprehensively concluded that the Communist Party of China (CPC) United and led the people of China to create the great achievements of the new-democratic revolution, socialist revolution and construction, reform and opening up and socialist modernization, and Socialism with Chinese characteristics in the new era.

These great achievements have made China grow from a "sick man of East Asia" who is bullied by others to an oriental power that makes the world sit up and take notice, and from a bystander of the international system to a builder of world peace, a contributor to global development and a defender of the international order … … It was under the strong leadership of the Communist Party of China (CPC) that China approached the center of the world stage step by step.

After a hundred years’ history, looking back has changed a lot. As General Secretary of the Supreme Leader said, "China has been able to look down on the world", and Chinese has more ambition, backbone and confidence to make a solemn declaration to the world!

"Centennial answer sheet" contains great spirit.

People can’t stand without spirit, and countries can’t stand without spirit. A hundred years after the founding of the Party, a large number of revolutionary martyrs, a large number of heroic figures with tenacious struggle and a large number of advanced models with selfless dedication have emerged.

There is Li Dazhao who firmly believes that "if you look at the world in the future, it will be a world with red flags"; Yang Jingyu, who was in a world of ice and snow, ran out of ammunition and was alone in a bloody battle with the Japanese aggressors; There are Wang Ganchang, Deng Jiaxian and other anonymous "two bombs and one satellite" fathers; There is Jiao Yulu, who is in the late stage of liver cancer and sticks to his liver to keep working; There are Wang Jicai, Gu Wenchang, Nan Rendong, Huang Wenxiu … …

General Secretary of Supreme Leader once solemnly stated that the great spirits such as Jinggangshan spirit, Long March spirit, Zunyi Conference spirit, Yan ‘an spirit, Xibaipo spirit, Hongyan spirit, the spirit of resisting US aggression and aiding Korea, the spirit of "two bombs and one satellite", the spirit of the special zone, the spirit of fighting floods, the spirit of earthquake relief and the spirit of fighting epidemics have built up the spiritual pedigree of the Communist Party of China (CPC) people.

Nowadays, the Communist Party of China (CPC) people’s spiritual pedigree is further enriched, and the General Secretary clearly put forward the 32-word great party-building spirit at the celebration of the centenary of the founding of the Communist Party of China (CPC).

The great party-building spirit, generated with the great practice of communist party people from generation to generation, is the source of the Communist Party of China (CPC)’s spirit, leading countless communist party people to wave upon wave and China people to write the most magnificent epic in China.

Feeling the great spirit of party building is like touching the historical pulse of the Communist Party of China (CPC)’s century-long development.

On the eve of "July 1st", the Political Bureau of the Communist Party of China (CPC) Central Committee conducted a special collective study around making good use of red resources and continuing the red vein. General Secretary of the Supreme Leader said earnestly: "The great spirit and glorious tradition of the Party are our precious spiritual wealth and a powerful spiritual driving force that inspires us to forge ahead bravely."

"Centennial Answer Sheet" continues to write a new journey.

The history of the Party is the most vivid and convincing textbook. The General Secretary of the Supreme Leader has repeatedly asked all party member to repair the compulsory course of Party history, and he himself has taken the lead in learning Party history.

In October 2017, shortly after the closing of the 19th National Congress of the Communist Party of China, General Secretary of the Supreme Leader made a special trip to Shanghai and Zhejiang to pay tribute to the site of the First Congress of the Communist Party of China and the Nanhu Red Boat, and led Comrade The Politburo Standing Committee (PSC) to review the pledge of joining the Party.

今年6月18日，总书记专程来到新落成的中国共产党历史展览馆，察看一件件文物实物，倾听一个个党史故事，又一次带领中央领导同志重温入党誓词。

回望奋斗之路，眺望新的征程。如何以史为鉴、开创未来？最高领袖总书记在庆祝中国共产党成立一百周年大会上提出“九个必须”，为新的伟大征程指明前进方向。

“中国人民也绝不允许任何外来势力欺负、压迫、奴役我们，谁妄想这样干，必将在14亿多中国人民用血肉筑成的钢铁长城面前碰得头破血流！”

“任何人都不要低估中国人民捍卫国家主权和领土完整的坚强决心、坚定意志、强大能力！”

…………

最高领袖总书记的铿锵话语，赢得了天安门广场上潮水般的掌声和热烈的欢呼声！

“时代是出卷人，我们是答卷人，人民是阅卷人。”建党百年，中国共产党向人民、向历史交出了一份优异答卷。

今天，向着实现第二个百年奋斗目标，中国共产党踏上了新的赶考之路，开始书写新时代的历史答卷。

（中央广播电视总台央视网）

The commendation meeting of the 2016 Shanghai Key Project Practical Meritorious Competition was held this morning (January 12). Before the meeting, Han Zheng, secretary of the Shanghai Municipal Party Committee, met with representatives of advanced collectives and individuals. Han Zheng said,2017 is the year of deepening the "Thirteenth Five-Year Plan". It is hoped that advanced collectives and individuals will play a leading and exemplary role, always adhere to safety first, quality first, management first, science and technology leading, and make greater contributions to building Shanghai into a more beautiful city and making people’s lives happier.

On the morning of January 12th, Han Zheng, secretary of the Shanghai Municipal Party Committee, met with representatives of advanced collectives and individuals. The pictures in this article are all Chen Zhengbao’s pictures.

Shanghai leaders Yang Xiong, Wu Zhiming, Ying Yong, Yin Hong, Xue Chao and Li Yiping, and Shanghai Garrison Political Commissar Ma Jiali attended the meeting.

On behalf of the Shanghai Municipal Party Committee, the Municipal People’s Congress, the Municipal Government and the CPPCC, Han Zheng congratulated the advanced collectives and individuals who were commended for their meritorious deeds in key projects, paid tribute to the vast number of urban builders and managers who fought in the front line all the year round, and expressed gratitude to the general public who understood, cared for and supported urban construction and major projects. He said that at this time of the year, we review the course of Shanghai’s key projects’ practical meritorious deeds competition, feel the hardships and share the joy of success. Since China’s reform and opening-up, especially since Pudong’s development and opening-up, Shanghai’s key projects have been closely focused on making up the shortcomings and facing the future development, constantly pushing forward, laying a solid foundation for the city’s economic and social development. This year is the year of deepening the 13th Five-Year Plan. According to the requirements of the central authorities, Shanghai is striving to be the vanguard of national reform and opening up and the pioneer of innovation and development, and is striving to basically build the "four centers" and a socialist modern international metropolis by 2020. The field of urban construction shoulders heavy responsibilities. Hope that advanced collectives and individualsAlways adhere to safety first, quality first, safety is the bottom line, and quality is life. We must always tighten the string of safety and continue to play a benchmark and leading role in key projects and practical projects with the world’s advanced level as the standard. Always adhere to management as the priority and science and technology as the guide, put management in a more important position to ensure safety and quality, highlight scientific and technological innovation, and improve the quality of the city. Always adhere to the people-friendly and civilized construction, and try to minimize the impact on the orderly operation of the city and the normal life of the citizens during the construction process.

At the commendation meeting, Yang Xiong said that last year, the achievements of major projects and practical projects in this city were gratifying, the shortcomings of urban management were remarkable, and the task of aiding Xinjiang was successfully completed, achieving the "Thirteenth Five-Year Plan" and "a good start". This year is an important year for implementing the 13th Five-Year Plan and deepening the structural reform on the supply side. Facing the new situation, we should conscientiously implement the general tone of striving for progress while maintaining stability, sum up experience, blaze new trails, roll up our sleeves and go all out to complete various construction tasks.

"Safety and quality are the lifeline of major engineering construction and must always be put in the first place." Yang Xiong pointed out that it is necessary to pay strict attention to construction safety, take effective measures, consolidate the main safety responsibilities of construction, survey, design, construction and supervision, pay close attention to key construction links, and strengthen the safety control of major risk sources. It is necessary to continuously improve the quality of the project, adhere to the international first-class benchmarking, comprehensively consider the design, construction and operation, adopt more advanced international quality standards, vigorously carry forward the craftsman spirit, and strive to create more excellent projects. To improve the level of civilized construction, the construction unit should further strengthen the overall awareness, focus on improving internal management, reduce related social costs, and minimize the impact of engineering construction on the city. The construction of rail transit stations should strive to occupy less roads and return them early. It is necessary to strengthen dust control on construction sites and roads, and urge transportation enterprises to reduce "leakage" in muck transportation. We should persist in scientific and technological innovation and promote the transformation and upgrading of the construction industry. To become an important carrier of scientific and technological innovation, major projects should promote prefabricated buildings in major projects throughout the city, and constantly increase the proportion of prefabricated components used in each project. It is necessary to speed up the popularization of building information model technology (BIM), and establish and improve the matching project approval mode and standard system. It is necessary to make more use of new technologies such as the Internet of Things and big data to explore intelligent life cycle management of buildings.

Shanghai leaders Ying Yong and Xue Chao, and Yi Li Pinghe Garrison leader Ma Jiali attended the meeting. A number of advanced collectives and individuals who made outstanding contributions to the construction of major projects and practical projects in this city in 2016 were commended.

It is reported that in 2016, 122 major engineering projects in the city were comprehensively promoted. By the end of December of that year, a total investment of 128.01 billion yuan had been completed, and 123.6% of the plan was completed at the beginning of the year.

On the afternoon of March 28th, the State Council Joint Prevention and Control Mechanism held a press conference to introduce the vaccination and supply guarantee in COVID-19. As of March 27th, 2021, 102.417 million doses of Covid-19 vaccine have been reported in various places.

About COVID-19 vaccine, the conference also introduced these latest news.

1. What should I do if I am not sure if I am suitable for vaccination?

If it really belongs to the vaccination taboo, it is impossible to provide vaccination services. If it is listed in the vaccination items, it is recommended to tell the vaccination doctor truthfully before vaccination. So that doctors can fully evaluate and determine whether it is suitable for vaccination.

2. How long is the vaccine protection period?

COVID-19 vaccine is a new vaccine. According to the antibody level, it will be monitored for more than six months. But we also know that antibody is not the only protective indicator, and there are other factors in the process of vaccine’s function. Therefore, we should do relevant research on the persistence of the vaccine to confirm how long its protection period is.

3. I have been vaccinated with COVID-19 vaccine. Do I need to be vaccinated again?

According to Zhongsheng of Sinopharm, during the whole clinical research, it is now observed that the persistence of vaccine protection is about half a year, and the persistence of neutralizing antibodies is also about half a year. In the clinical process of the overall design, the booster needle was designed to observe the persistence and protection level of antibodies. At present, the preliminary results show that booster needle can effectively improve the titer of neutralizing antibodies, effectively improve the persistence of antibodies, and also effectively improve the anti-mutation ability of vaccines.

In the future, phase III clinical research will be carried out overseas to continuously observe the persistence of antibodies and protection. Is it necessary to carry out booster vaccination? When will you call? Still have to answer according to the results of the next three clinical studies.

4. What is the preventive effect of COVID-19 vaccine?

The vaccine itself can prevent infection, morbidity, severe illness and death. Now, the effectiveness result we get is the result of our clinical experiment. With the application of the vaccine, we will also carry out related research on its protective effect after marketing.

5. How to ensure the supply of vaccines in COVID-19?

On the one hand, actively and steadily expand the vaccination service capacity, optimize the vaccine distribution process, and improve the efficiency of circulation and operation. To scientifically arrange the turnover quantity of vaccines, the requirement is not to overstock the inventory, and to increase the number of inoculation points and inoculation stations in various ways to meet the vaccination needs of the masses. On the other hand, it is necessary to strengthen the linkage between departments and coordinate the industrial and information departments to strengthen the supply guarantee of vaccines.

6. After the first injection, how long is the best time to inject the second injection?

After the first dose of vaccination, the interval between the second dose of vaccination should be greater than or equal to three weeks, and the second dose of vaccination should be completed as soon as possible within 8 weeks after the first dose of vaccine.

7. If you catch up with a business trip or go out, can you get a second shot in a different place?

According to the guidelines, it is recommended to use the varieties of the same enterprise as much as possible to complete two doses of vaccination. If the same variety is not available in different places, then other vaccine products of the same kind can be replaced to complete two doses of vaccination.

Effective period

8. If I miss the second dose of vaccination for some reason, how can I make it up?

For those who have not completed 2 or 3 doses of COVID-19 vaccine according to the procedure, it is suggested to replant as soon as possible. There is no need to restart the immunization program, just replant and complete the corresponding dose.

9. Some vaccine developers have been vaccinated in February and March last year. What are the antibodies in these people?

Some people, as the vanguard of vaccines, have been vaccinated with inactivated vaccines in COVID-19. We are constantly monitoring the change data of antibodies in their bodies. At present, we have obtained the antibody monitoring data for 9 months. Judging from the current data, the antibodies in 9 months still have a certain level. We will continue to strengthen monitoring in the future.

10. Will foreign virus variation affect the effectiveness of existing vaccines?

Vaccine research and development units and production units pay great attention to dealing with the variation problem. Two inactivated vaccines of Sinopharm Group China Bio, using the serum after the second and third clinical trials at home and abroad, have carried out cross-comprehensive experiments on the strains found in South Africa and Britain, as well as more than 10 strains found in different regions and epidemic areas in China. The results show that neutralizing antibodies produced by the two inactivated vaccines have a good neutralizing effect on these strains. Small variation of the virus will not affect the antigenicity of the vaccine, that is, the vaccine will be effective without variation of protective antigen, especially the whole virus inactivated vaccine.

11. How to advance the national plan for vaccination of the elderly?

At present, Beijing, Shanghai and other regions have been vaccinated with Covid-19 vaccine for some elderly people over 60 years old and patients with chronic diseases who are willing to be vaccinated and in good physical condition under the premise of fully evaluating the health status and infection risk of the vaccinated objects. In the next step, we will actively and steadily promote the vaccination of people over 60 years old and patients with chronic diseases in combination with the use effect of vaccines in large-scale populations.

12. When will people under the age of 18 be vaccinated?

Last year, the phase I/II clinical research conducted by China Bio in Henan covered the systematic, safe and immunogenic clinical research of the young age group of 3-17 years old. At present, the safety data of this age group have been completely obtained, and the expected results have been achieved. The detection of immunogenicity and neutralizing antibodies has also been completed. We will communicate with the Food and Drug Administration in the near future, and I believe that this group of people can be covered in the near future.

(Source: Henan CDC)

Original title: "12 questions about COVID-19 vaccine, look at the answer"

Read the original text

　　CCTV News:At present, the flu season has entered, and the level of flu activity has been on the rise recently. However, everyone has some misunderstandings about the flu. Let’s sort it out.

　　Myth 1: This year’s flu is more serious than in previous years.

　　Every winter and spring is the high incidence of influenza. According to the monitoring data released by China CDC, the overall activity level of influenza in China is lower than that in the same period of last year, and will show a downward trend from the end of this month.

　　Song Tie, Deputy Director of Guangdong CDC.: "It is mainly influenza A (H1N1) virus. There are many outbreaks in primary schools this year, but at present, with the school holidays, this outbreak will gradually decrease."

　　Myth 2: This year’s influenza virus variants are easy to cause complications.

　　In the past two days, many parents have been fidgeting because of the news that "the flu virus turned to attack children’s brains this year". Does this year’s influenza virus mutate, and is it easy to cause complications? China CDC said that at present, no variation of influenza virus has been found in various places.

　　Whether you will get complications after suffering from the flu depends on the patient’s own resistance and the power of the virus. Generally speaking, influenza may cause pneumonia, myocarditis, or central nervous system diseases including encephalitis. This is not a new situation this year, so there is no need for excessive panic. However, these five groups of people should pay special attention. They are more likely to get flu complications than ordinary people and belong to high-risk groups.

　　1. Children under 5 years old

　　2. Older people over 65 years old

　　3. Patients with chronic diseases and immune diseases

　　4. Obese people

　　5. Pregnant women

　　Myth 3: Strong people don’t have to be afraid of the flu.

　　Doctors said that people who are strong and have strong resistance should not think that their chances of getting the flu are low, so they don’t pay attention to rest and prevention, so that the virus also has the opportunity to take advantage of it, such as fatigue, hunger, or soaking clothes after sweating a lot. Among influenza complications, the incidence of myocarditis is higher in healthy young adults. This is because these people are more immune, and when they are invaded by the virus, their own defense system will also damage myocardial cells while removing the virus.

　　Myth 4: Influenza is treated as a common cold.

　　The doctor said that the symptoms of the common cold are mild, and most of them are respiratory symptoms such as sore throat, cough and stuffy nose, while the flu is accompanied by high fever above 38℃, chills, dizziness and headache, muscle aches, etc., and it is highly contagious. Once you have cold symptoms, you should go to the hospital for examination and diagnosis, and prescribe the right medicine. At present, antiviral drugs for influenza are prescription drugs, which must be taken under the guidance of a doctor. Antibiotics have no effect on influenza.

　　Myth 5: relying on "remedies" such as vinegar fumigation to prevent influenza

　　In order to prevent the flu, some people smoke vinegar at home. The doctor said that acetic acid can only kill bacteria when it reaches a certain concentration. Moreover, the flu virus is not a bacterium, and it cannot be killed by acetic acid at all. Blind vinegar fumigation will also aggravate the condition of patients with bronchitis and emphysema.

　　Others rely on oral vitamin C to prevent influenza. Doctors say that taking enough fruits and vegetables has the same effect as oral vitamin C, which can improve immunity, but it has no antiviral effect. According to the method of drinking Radix Isatidis and other traditional Chinese medicines to prevent influenza, the doctor said that Radix Isatidis is cool and not beneficial to all patients.

　　Yang Shuyu, President of Xiamen Medical Association, Fujian: "When a cold is prevalent, it is very important to pay attention to improving your immunity, instead of blindly taking drugs, which will affect and damage your immunity."